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Self-Experimentation
Share your story of trying or designing a promising age-reversal protocol.
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About this forum topic
Hello everyone, Many of us are self-experimenting in an effort to prolong our good health. In this sub-forum, we encourage you to share your own stories of what seems to be working for you.…
Maximus Peto
Researcher, website & forum admin
Maximus
6 yrs ago
1229
15
Self-Experimentation
Fisetin to Clear Senescent Cells
Following studies with mice that showed significant senolytic clearance of senescent cells following large doses of the readily available flavenoid supplement Fisetin,…
JGC
Retired Professor of Physics
JGC
updated
3 yrs ago
766
replies
19040
20
Last reply
Dan Nave
1 yr ago
Self-Experimentation
Rapamycin Cost
Let me clear some things up for people considering rapamycin (generic sirolimus). I am taking it and so are my dogs!! (I have a very open-minded vet who trusts my judgement.) Dr.…
Rob8311
Rob8311
6 yrs ago
599
replies
14014
14
Last reply
Steve Roedde
1 yr ago
Self-Experimentation
Just Ordered Rapamycin w/ No Prescription
When I was at Raadfest18, it was announced that there was a vendor in the Exhibition Hall from whom Rapamycin could be ordered at a good price. Later I found out exactly what vendor from someone…
Mermaid
Mermaid
5 yrs ago
80
replies
6794
5
Last reply
Steve Roedde
1 yr ago
Self-Experimentation
How to increase the bioavailability of Fisetin
I'm preparing to do a Fisetin senolytic experiment, but I've read on the article from Mayo Clinic ( https://linkinghub.elsevier.com/retrieve/pii/S2352396418303736 ) that the administration mode was…
JPA
JPA
5 yrs ago
110
replies
6439
3
Last reply
Robert Uomini
2 yrs ago
Self-Experimentation
GlyNAC
Has anyone tried Glycine/N-acetylcysteine? It appears to have amazing effects on age reversal. Glycine and N‐acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency,…
Qimin You
Qimin_You
3 yrs ago
103
replies
5243
3
Last reply
martino lorenzon
9 mths ago
Self-Experimentation
Senolytics
I've just finished my third Senolytic cycle. Fisetin 1500 mgs on 2 consecutihve days repeated one month later Dasatinab 180 mgs on 2 consecutive days + Quercitn 2250 mgs on the same days I also take…
Charles Grashow
Charles_Grashow
4 yrs ago
128
replies
4212
8
Last reply
Wil
2 yrs ago
Self-Experimentation
Rapamycin self-experimentation
I've just begun a 10 week self-experimentation with RapaPro rapamycin. I'll be taking 5 mg once a week, which is roughly the dose that Dr. Alan Green recommends on the high side and seems to be…
Tam
Tam
4 yrs ago
74
replies
3608
5
Last reply
Ludovic Debels
3 yrs ago
Self-Experimentation
Rapamycin - progress so far
Hi all, About me: I'm 46 y.o. medical doctor based in Europe and started taking weekly rapamycin 4 months ago. I go to the gym regularly and am in average physical condition for a guy of my age.…
Diamond Tree
Diamond_Tree
updated
2 yrs ago
86
replies
3156
7
Last reply
Jonas Huberman
9 mths ago
Self-Experimentation
Anyone actually experience marked increased energy from NMN?
It's been 2 years now - sublingual. Nothing. I'm ready to throw it in the box with the resveratrol and rapamycin. Please leave your experiences and types/doses as well as how you can differentiate…
Michael
Michael.1
2 yrs ago
139
replies
2794
Last reply
chuck stanley
10 mths ago
Self-Experimentation
Dasatinib
Hi Brian, On the website "SocietyforAgeReversal.org which is the same as rescueelders.org I think. You mentioned in the blog, "I'm taking a very quick break from the engaging presentations to report…
Snowbird
Snowbird
5 yrs ago
113
replies
2561
2
Last reply
Rob8311
2 yrs ago
Self-Experimentation
Photo evidence that the experiment is working
Correct me if I'm wrong. I figured that this deserves it's own discussion topic. More than 5 years ago I started doing age-reversal. Couple of years back when I realized that it was working I…
Andrew P K Yap
Andrew_P_K_Yap
2 yrs ago
109
replies
2311
3
Last reply
Andrew P K Yap
2 mths ago
Self-Experimentation
wrinkle reduction
has anyone noticed wrinkle reduction in systemic use of sirolimus?
curious
curious
3 yrs ago
107
replies
2092
3
Last reply
Hello World
2 yrs ago
Self-Experimentation
"Senolytic Activator" and Extended Fasting …
Gentlefolk, Our fine friends at Life Extension have released a new product, Senolytic Activator. It is a combination of Quercertin and Theaflavins. They intend us to use it weekly as a…
adonoho
adonoho
5 yrs ago
36
replies
1930
6
Last reply
Marc Bauchet
2 yrs ago
Self-Experimentation
Has anyone tried urolithin A?
Urolithin A is a bacterial metabolite that enhances mitophagy, which declines as we age and allows dysfunctional mitochondria to accumulate. I just wanted to see if anyone has experimented with…
Will Hunter
Will_Hunter
3 yrs ago
31
replies
1526
2
Last reply
Karl
1 yr ago
Self-Experimentation
Rapamycin Side Effect
Just read a recent addition to Dr. Green's site. I'll just post part of what he says. I don't get the impression he thinks it is a reason to stop treating, but important to be aware of.…
Rob8311
Rob8311
5 yrs ago
67
replies
1364
3
Last reply
Vincent Stona
4 yrs ago
Self-Experimentation
Paul's Anti-Aging Efforts
Preparing for a LONG FUTURE, here are the prescriptions and supplements I take to STOP or REVERSE AGING, with the blessings of my doctors. After each one are the number of Web sites mentioning them,…
Paul Mason
Paul_Mason
5 yrs ago
12
replies
1362
4
Last reply
Simon Lee
3 yrs ago
Self-Experimentation
Metformin: worth it? and what to expect
Hello all. I got my Doctor to give me a prescription for Metformin. I have read about its possible age-reversing effects, but I have also read about some possible significant side effects,…
Jeff Bennion
Jeff_Bennion
updated
5 yrs ago
35
replies
1357
1
Last reply
Cherith
4 yrs ago
Self-Experimentation
Is spontaneous hair colour restoration normal?
So, I am a 44yo male with a speckling of grey hair, and I have been taking a mix of compounds that are often discussed in the forums. I started in about mid-January this year.…
David Ng
David_Ng
updated
2 yrs ago
17
replies
1348
2
Last reply
Allen DeLaney
2 mths ago
Self-Experimentation
Paul's self experimentation
I inadvertently started on this 5 years ago when I started taking Metformin. Was diagnosed with a Gleason 6 prostate cancer. Docs didn't want to treat just monitor.…
Paul Beauchemin
Paul_Beauchemin
4 yrs ago
66
replies
1288
3
Last reply
Alex
1 yr ago
Self-Experimentation
Anti-Aging Self-Experiment with Epitalon (AEDG)
There is a body of evidence, coming primarily from the publications of Vladimir Kh. Khavinson and his group at the Institute of Bioregulation and Gerontology (IB&G) in Moscow,…
JGC
Retired Professor of Physics
JGC
3 yrs ago
25
replies
1187
6
Last reply
Burgundy Summer
2 yrs ago
Self-Experimentation
Possible negative response to oral NAD+
Hello, My wife and I (~50) have started a NAD+ regime in addition to rest of the other life long regime (vegan, exercise, other suppls). We started with 250mg (sourced from Life Extension),…
Dan
moderator
skipping my funeral
dantheman
5 yrs ago
18
replies
1125
2
Last reply
Jay Orman
10 mths ago
Self-Experimentation
Preparations for self-treating COVID-19
The mortality rate of the aged population from COVID-19 is very high, around 20% for the over-80 group of which I and my wife are members. Further, if medical facilities are limited and physicians…
JGC
Retired Professor of Physics
JGC
4 yrs ago
88
replies
1116
3
Last reply
Vic Emmay
3 mths ago
Self-Experimentation
Where to buy rapamycin?
Hey everyone, I’m new to the group. Really cool to see everyone’s experience with Rapamycin. I’m looking to get some myself. I’m actually more interested in it for my cat’s heart condition.…
Stefan Pougatchev
Stefan_Pougatchev
2 yrs ago
21
replies
1110
2
Last reply
Karina
1 yr ago
Self-Experimentation
Sources for Metformin?
Suggestions? The best source is via your GP. I have script for Metformin due to an undiscovered elevated glucose (check yours first thing in the morning,…
Dan
moderator
skipping my funeral
dantheman
updated
4 yrs ago
27
replies
1067
2
Last reply
Mermaid
4 yrs ago
Self-Experimentation
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