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Self-Experimentation

Share your story of trying or designing a promising age-reversal protocol.

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Hello everyone, Many of us are self-experimenting in an effort to prolong our good health. In this sub-forum, we encourage you to share your own stories of what seems to be working for you.…
- Maximus Peto
- Researcher, website & forum admin
- Maximus
- 4 yrs ago
- 1,106
- 15
- Self-Experimentation
Are these issues related to rapamycin
Hello there and thank you to all on the forum, I am finding it enormously helpful directing my self experimentation. I am 53 with a string family history of dementia I am trying to stave off.…
- Dr Sian Klerk
- Dr_Sian_McIver
- 3 wk ago
- 11 replies
- 120
- Karlyesterday
- Self-Experimentation
Yeast-Displayed GDF11 and Oral Delivery
Through the work of Steve Perry, it appears that taking growth differentiation factor 11 (GDF11) provides definite health benefits and some evidence of rejuvenation.…
- JGC
- JGC
- 2 mths ago
- 4 replies
- 94
- 1
- Jay Orman8 days ago
- Self-Experimentation
Tracking daily steps
Just got on the steps band wagon. Who is tracking their daily steps? What are you averaging? What changes have you noticed? To provide some value, here's a link. https://www.nih.…
- Michael
- Michael.1
- 4 wk ago
- 4 replies
- 65
- Michael2 wk ago
- Self-Experimentation
Blood Test #4 in 2022: Supplements, Diet
https://www.youtube.com/watch?v=RFGtc6cj1AU
- michael lustgarten
- michael_lustgarten
- 2 wk ago
- 25
- Self-Experimentation
The DIM Supplement and Wound Healing
Forgive me for introducing a topic to this Forum that is slightly off the topic on anti-aging. The supplement DIM (3, 3,-diindolylmethane) sold by Swanson ($8.…
- JGC
- JGC
- 2 wk ago
- 4 replies
- 60
- 3
- chuck stanley2 wk ago
- Self-Experimentation
Blood Test #1 in 2022: Supplements, Fitness, Diet
https://www.youtube.com/watch?v=46_Xkj9xQug
- michael lustgarten
- michael_lustgarten
- 6 mths ago
- 3 replies
- 90
- 1
- shirleyscaringi2 wk ago
- Self-Experimentation
Rapamycin and shingles, is there a connection
I have a question about the effects of rapamycin and whether it may play a part in my attack of shingles. I am 53 and have been self experimenting with 6mg a day augmented with grapefruit juice for…
- Dr Sian Klerk
- Dr_Sian_McIver
- 3 wk ago
- 16
- Self-Experimentation
Current longevity protocol: Should I add rapamycin?
This is my first post here, and I’m hoping to get some insights from people with similar protocols. In particular, I’m curious to hear people’s perspective on rapamycin given my current regimen.…
- Simon Smith
- Simon_Smith
- 10 mths ago
- 26 replies
- 457
- 2
- Peter H. Howe3 wk ago
- Self-Experimentation
Rapamycin - progress so far
Hi all, About me: I'm 46 y.o. medical doctor based in Europe and started taking weekly rapamycin 4 months ago. I go to the gym regularly and am in average physical condition for a guy of my age.…
- Diamond Tree
- Diamond_Tree
- 11 mths ago
- 75 replies
- 2,075
- 7
- chuck stanley1 mth ago
- Self-Experimentation
Self Administered Anesthetic Dental Injections
Anyone have experience with it? Any recommendations on administration and compounds used? Thank you, CHAMPIONS!
- Michael
- Michael.1
- 5 mths ago
- 3 replies
- 114
- Michael4 mths ago
- Self-Experimentation
Best Free Online Tool to Check Blood Work - Exhaustive would be nice.
Any suggestions? Thank you!
- Michael
- Michael.1
- 1 mth ago
- 11
- Self-Experimentation
Biomarkers for those taking Rapamycin....?
Hi all, can I ask what biomarkers those of you who are taking Rapamycin are testing and frequency etc? I've had a quick search but can't seem to find anything.…
- Natalie S
- Natalie_S
- 1 mth ago
- 3 replies
- 60
- Brin Chikovski1 mth ago
- Self-Experimentation
Self-experimentation with variety of supplements and drugs
Greetings, I am 67, male, with type 2 diabetes, heart disease and high blood pressure. Current prescription drugs I take per doctor's order: 2000 mg metformin, 45 mg actos, 80 mg lipitor, 2.…
- Kim Mackey
- Kim_Mackey
- 3 yrs ago
- 4 replies
- 524
- JOHN2 yrs ago
- Self-Experimentation
Cosmetic Peptides
Anyone have experience with any of the (cosmetic) peptides on this site or equivalent? Tried the rapa cream formula suggested on the forum here with zero benefit.…
- Michael
- Michael.1
- 1 yr ago
- 3 replies
- 169
- 1
- Rick Tolk1 mth ago
- Self-Experimentation
D+Q+F+P+L+G+GLA: A New Senolytic Cocktail
For my May 15-18 senolytic session I tried something new. In a recent Foresight Institute talk available on YouTube, James Kirkland identified the flavonoid Luteolin as a senolytic.…
- JGC
- JGC
- 2 mths ago
- 32 replies
- 472
- 4
- John Hemming1 mth ago
- Self-Experimentation
Protocol which makes senescent cells start to function and hair to grow
https://johnhemming.blogspot.com/2022/06/protocol-which-makes-senescent-cells.html I have put a link to my blog post about my new protocol which is designed to get senescent cells to exit senescence…
- John Hemming
- John_Hemming
- 1 mth ago
- 2 replies
- 122
- 2
- John Hemming1 mth ago
- Self-Experimentation
Albumin: What's Optimal For Youth And Health? (2022 Update)
https://www.youtube.com/watch?v=Q3PXBl82uTk
- michael lustgarten
- michael_lustgarten
- 1 mth ago
- 29
- Self-Experimentation
D.I.Y. patches for supplement delivery
Is anyone else interested in making your own patches for supplement delivery? Patches are not strictly about age-reversal. They can be used for other vitamins & supplements, too.…
- Mike Almerjanski
- Mike_Almerjanski
- 2 yrs ago
- 8 replies
- 323
- 3
- Joe2 mths ago
- Self-Experimentation
Fisetin to Clear Senescent Cells
Following studies with mice that showed significant senolytic clearance of senescent cells following large doses of the readily available flavenoid supplement Fisetin ,…
- JGC
- JGC
- 2 yrs ago
- 742 replies
- 16,436
- 20
- Staffan Olsson2 mths ago
- Self-Experimentation
Dasatinib update
Just finished a 3 day course of D & Q. The Dasatinib was purchased from Taylor Made Compounding. Dosage was 100 mg D &1000 mg Q. Cost for 6 @50 mg capsules, including shipping was USD $33.…
- Charles Grashow
- Charles_Grashow
- 1 yr ago
- 21 replies
- 659
- 1
- Jared2 mths ago
- Self-Experimentation
Where to buy rapamycin?
Hey everyone, I’m new to the group. Really cool to see everyone’s experience with Rapamycin. I’m looking to get some myself. I’m actually more interested in it for my cat’s heart condition.…
- Stefan Pougatchev
- Stefan_Pougatchev
- 9 mths ago
- 21 replies
- 583
- 2
- Karina2 mths ago
- Self-Experimentation
Is spontaneous hair colour restoration normal?
So, I am a 44yo male with a speckling of grey hair, and I have been taking a mix of compounds that are often discussed in the forums. I started in about mid-January this year.…
- David Ng
- David_Ng
- 5 mths ago
- 15 replies
- 552
- 2
- Jack Black2 mths ago
- Self-Experimentation
Has anyone tried urolithin A?
Urolithin A is a bacterial metabolite that enhances mitophagy, which declines as we age and allows dysfunctional mitochondria to accumulate. I just wanted to see if anyone has experimented with…
- Will Hunter
- Will_Hunter
- 1 yr ago
- 31 replies
- 837
- 2
- Karl2 mths ago
- Self-Experimentation
GlyNAC
Has anyone tried Glycine/N-acetylcysteine? It appears to have amazing effects on age reversal. Glycine and N‐acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency,…
- Qimin You
- Qimin_You
- 1 yr ago
- 89 replies
- 2,336
- 3
- Charles Richardson2 mths ago
- Self-Experimentation
Rapamycin Cost
Let me clear some things up for people considering rapamycin (generic sirolimus). I am taking it and so are my dogs!! (I have a very open-minded vet who trusts my judgement.) Dr.…
- Rob8311
- Rob8311
- 4 yrs ago
- 599 replies
- 12,877
- 14
- Steve Roedde2 mths ago
- Self-Experimentation

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