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Self-Experimentation

Share your story of trying or designing a promising age-reversal protocol.

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Hello everyone, Many of us are self-experimenting in an effort to prolong our good health. In this sub-forum, we encourage you to share your own stories of what seems to be working for you.…
- Max Peto
- Researcher, website & forum admin
- Maximus
- 4 yrs ago
- 1,088
- 15
- Self-Experimentation
D.I.Y. patches for supplement delivery
Is anyone else interested in making your own patches for supplement delivery? Patches are not strictly about age-reversal. They can be used for other vitamins & supplements, too.…
- Mike Almerjanski
- Mike_Almerjanski
- 2 yrs ago
- 7 replies
- 282
- 2
- Leanne Gilbert5 hrs ago
- Self-Experimentation
Fisetin to Clear Senescent Cells
Following studies with mice that showed significant senolytic clearance of senescent cells following large doses of the readily available flavenoid supplement Fisetin ,…
- JGC
- JGC
- 1 yr ago
- 729 replies
- 15,676
- 20
- Juan Daw19 hrs ago
- Self-Experimentation
Sea squirts, mussels and longevity
https://neurosciencenews.com/aging-sea-squirts-20570/#:~:text=They%20found%20that%20the%20supplements,impairments%20in%20the%20aging%20brain . As the article suggests,…
- Juan Daw
- saxxnviolins
- 3 days ago
- 5 replies
- 52
- Fred Cloudyesterday
- Self-Experimentation
Any results from D & Q course?
Has anyone noticed any perceivable results from a D & Q treatment?
- Jared
- Jared77
- 3 mths ago
- 20 replies
- 284
- phil byers2 days ago
- Self-Experimentation
Gingernone A is a Better-than-D+Q Senolytic
A post in Lifespan.io discusses a recent paper published last month in PLoS One in which the polyphenol Gingernone A, a strong component of Ginger Root Extract ,…
- JGC
- JGC
- 1 mth ago
- 8 replies
- 225
- 3
- Karl2 days ago
- Self-Experimentation
GlyNAC
Has anyone tried Glycine/N-acetylcysteine? It appears to have amazing effects on age reversal. Glycine and N‐acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency,…
- Qimin You
- Qimin_You
- 1 yr ago
- 86 replies
- 2,076
- 3
- Chris M6 days ago
- Self-Experimentation
wrinkle reduction
has anyone noticed wrinkle reduction in systemic use of sirolimus?
- curious
- curious
- 1 yr ago
- 108 replies
- 1,768
- 3
- Sky Inka7 days ago
- Self-Experimentation
Just Ordered Rapamycin w/ No Prescription
When I was at Raadfest18, it was announced that there was a vendor in the Exhibition Hall from whom Rapamycin could be ordered at a good price. Later I found out exactly what vendor from someone…
- Mermaid
- Mermaid
- 3 yrs ago
- 80 replies
- 4,467
- 5
- Steve Roedde8 days ago
- Self-Experimentation
Photo evidence that the experiment is working
Correct me if I'm wrong. I figured that this deserves it's own discussion topic. More than 5 years ago I started doing age-reversal. Couple of years back when I realized that it was working I…
- Andrew P K Yap
- Andrew_P_K_Yap
- 9 mths ago
- 67 replies
- 1,254
- 3
- Andrew P K Yap2 wk ago
- Self-Experimentation
Where to buy rapamycin?
Hey everyone, I’m new to the group. Really cool to see everyone’s experience with Rapamycin. I’m looking to get some myself. I’m actually more interested in it for my cat’s heart condition.…
- Stefan Pougatchev
- Stefan_Pougatchev
- 6 mths ago
- 12 replies
- 421
- 1
- Theresa2 wk ago
- Self-Experimentation
Rapamycin Cost
Let me clear some things up for people considering rapamycin (generic sirolimus). I am taking it and so are my dogs!! (I have a very open-minded vet who trusts my judgement.) Dr.…
- Rob8311
- Rob8311
- 4 yrs ago
- 594 replies
- 12,453
- 14
- Van2 wk ago
- Self-Experimentation
Testosterone Trials
The Testosterone Trials were a set of seven randomized placebo-controlled trials that evaluated the efficacy of testosterone replacement therapy (TRT) in older men with low testosterone levels,…
- Michael
- Michael.1
- 5 mths ago
- 6 replies
- 215
- 1
- Michael3 wk ago
- Self-Experimentation
Recent constellation has had an effect... again
I wish I had more scientific data to bring, but in messy real life we end up trying various things and it muddies the waters. I've got existing benefits from a heap of stuff already,…
- Jack Black
- Jack_Black
- 1 mth ago
- 1 reply
- 61
- Jack Black3 wk ago
- Self-Experimentation
Is spontaneous hair colour restoration normal?
So, I am a 44yo male with a speckling of grey hair, and I have been taking a mix of compounds that are often discussed in the forums. I started in about mid-January this year.…
- David Ng
- David_Ng
- 2 mths ago
- 14 replies
- 372
- 2
- John Hemming4 wk ago
- Self-Experimentation
Astaxanthin - A proven life extending supplement?
New and unpublished data from the ITP (Interventions Testing Program) show that Astaxanthin is one of few substances that show life extending effects, At least when tested rigorously in the programs…
- Staffan Olsson
- Staffan_Olsson
- 1 mth ago
- 3 replies
- 127
- 1
- Staffan Olsson1 mth ago
- Self-Experimentation
Methylene blue
I wonder if somebody in this forum has experimented with Methylene blue and can report about the experiences made?
- Staffan Olsson
- Staffan_Olsson
- 1 mth ago
- 40
- Self-Experimentation
Self Administered Anesthetic Dental Injections
Anyone have experience with it? Any recommendations on administration and compounds used? Thank you, CHAMPIONS!
- Michael
- Michael.1
- 2 mths ago
- 3 replies
- 90
- Michael1 mth ago
- Self-Experimentation
blood work
OKAY BRAINIACS! After putting off doing blood Dr. Green requested for over a month, and going without fasting, what do these results indicate. 1) heavy smoker 2) Whiskey drinker 3) No breakfast.…
- Michael
- Michael.1
- 1 yr ago
- 21 replies
- 215
- Michael1 mth ago
- Self-Experimentation
Blood Test #1 in 2022: Supplements, Fitness, Diet
https://www.youtube.com/watch?v=46_Xkj9xQug
- michael lustgarten
- michael_lustgarten
- 3 mths ago
- 1 reply
- 54
- 1
- Ueniaspell1 mth ago
- Self-Experimentation
Autophagy / fasting
I've recently become aware of the importance of autophagy in the cells and the ability to promote or trigger this through fasting. Just started a 3 day fast yesterday (I'm doing the apple fast,…
- Phoebe Saffold
- Phoebe_Saffold
- 11 mths ago
- 3 replies
- 183
- Jack Black1 mth ago
- Self-Experimentation
Rapamycin & Covid
Recently the new Omicron BA2 variant busted through the triple vaxed fortress my family had built. I was ill for a few days, but never felt in danger. When the illness subsided I suffered from…
- Jack Black
- Jack_Black
- 1 mth ago
- 1 reply
- 53
- 1
- Jay Orman1 mth ago
- Self-Experimentation
Longevity Achieved
Recently received my results on my biological age. To my surprise, my biological age is 15. The process to get to this point was difficult. My formula has proven itself over and over.…
- Richard Brook
- Richard_Brook
- 10 mths ago
- 38 replies
- 890
- 1
- Spasov1 mth ago
- Self-Experimentation
Has anyone tried urolithin A?
Urolithin A is a bacterial metabolite that enhances mitophagy, which declines as we age and allows dysfunctional mitochondria to accumulate. I just wanted to see if anyone has experimented with…
- Will Hunter
- Will_Hunter
- 1 yr ago
- 29 replies
- 669
- 2
- Karl1 mth ago
- Self-Experimentation
Berberine and Melatonin - can this reverse aging of cells?
I am using an unusual mix of Melatonin (taken in the middle of the night,early morning really) and Berberine. This video explains the reasons why this has the potential to demethylate the epigenome…
- John Hemming
- John_Hemming
- 6 mths ago
- 9 replies
- 452
- 1
- John Hemming1 mth ago
- Self-Experimentation
Anyone actually experience marked increased energy from NMN?
It's been 2 years now - sublingual. Nothing. I'm ready to throw it in the box with the resveratrol and rapamycin. Please leave your experiences and types/doses as well as how you can differentiate…
- Michael
- Michael.1
- 10 mths ago
- 134 replies
- 1,636
- Alex K. Chen1 mth ago
- Self-Experimentation

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