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Self-Experimentation

Share your story of trying or designing a promising age-reversal protocol.

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Hello everyone, Many of us are self-experimenting in an effort to prolong our good health. In this sub-forum, we encourage you to share your own stories of what seems to be working for you.…
- Max Petomoderator
- Researcher, website & forum admin
- Maximus
- 2 yrs ago
- 810
- 14
- Self-Experimentation
wrinkle reduction
has anyone noticed wrinkle reduction in systemic use of sirolimus?
- curious
- curious
- 1 mth ago
- 60 replies
- 428
- 1
- Michael19 min ago
- Self-Experimentation
Fisetin to Clear Senescent Cells
Following studies with mice that showed significant senolytic clearance of senescent cells following large doses of the readily available flavenoid supplement Fisetin ,…
- JGC
- JGC
- 3 mths ago
- 432 replies
- 7,360
- 12
- garland2 hrs ago
- Self-Experimentation
Bio-Fisetin, a x25 Boost in Bioavailability?
One of the big problems with senolytic flavenoids like Fisetin and Quercetin is that they have a very low solubility in water and poor survival in the digestive tract,…
- JGC
- JGC
- 3 wk ago
- 11 replies
- 179
- 2
- Curtis Smith4 hrs ago
- Self-Experimentation
Senolytics
I've just finished my third Senolytic cycle. Fisetin 1500 mgs on 2 consecutihve days repeated one month later Dasatinab 180 mgs on 2 consecutive days + Quercitn 2250 mgs on the same days I also take…
- Charles Grashow
- Charles_Grashow
- 11 mths ago
- 127 replies
- 2,650
- 5
- garland2 wk ago
- Self-Experimentation
Paul's self experimentation
I inadvertently started on this 5 years ago when I started taking Metformin. Was diagnosed with a Gleason 6 prostate cancer. Docs didn't want to treat just monitor.…
- Paul Beauchemin
- Paul_Beauchemin
- 10 mths ago
- 48 replies
- 802
- 3
- Fred Cloud2 wk ago
- Self-Experimentation
RFID
Under the guise of self experimentation, everything you're taking, could be monitored; transmitting back. And, you're last man on the totem pole. I've been around long enough to have voted for…
- Michael
- Michael.1
- 3 wk ago
- 25
- Self-Experimentation
blood work
OKAY BRAINIACS! After putting off doing blood Dr. Green requested for over a month, and going without fasting, what do these results indicate. 1) heavy smoker 2) Whiskey drinker 3) No breakfast.…
- Michael
- Michael.1
- 3 wk ago
- 18 replies
- 100
- MAC3 wk ago
- Self-Experimentation
Dasatinib update
Just finished a 3 day course of D & Q. The Dasatinib was purchased from Taylor Made Compounding. Dosage was 100 mg D &1000 mg Q. Cost for 6 @50 mg capsules, including shipping was USD $33.…
- Charles Grashow
- Charles_Grashow
- 1 mth ago
- 10 replies
- 163
- Larry3 wk ago
- Self-Experimentation
Bkcaffee's experiment experience
I just received my dasatinib (70 mg ). Before I start taking it I'm wanting to contact a dr in the area (alabama) for review. In the meantime I'm gathering info to do this right.…
- Brandon Caffee
- Brandon_Caffee
- 1 mth ago
- 2 replies
- 64
- Jim N1 mth ago
- Self-Experimentation
Is it me or is Apigenin not so hot in this forum
Treatment of cells with apigenin or quercetin inhibits CD38 and promotes an increase in intracellular NAD+ levels. An increased NAD+ level decreases protein acetylation through sirtuin activation. ..…
- Andrew P K Yap
- Andrew_P_K_Yap
- 4 mths ago
- 19 replies
- 341
- micro20001 mth ago
- Self-Experimentation
Rapamycin Cost
Let me clear some things up for people considering rapamycin (generic sirolimus). I am taking it and so are my dogs!! (I have a very open-minded vet who trusts my judgement.) Dr.…
- Rob8311
- Rob8311
- 2 yrs ago
- 245 replies
- 5,960
- 8
- Ludovic Debels1 mth ago
- Self-Experimentation
Rapamycin self-experimentation
I've just begun a 10 week self-experimentation with RapaPro rapamycin. I'll be taking 5 mg once a week, which is roughly the dose that Dr. Alan Green recommends on the high side and seems to be…
- Tam
- Tam
- 1 yr ago
- 74 replies
- 2,328
- 4
- Ludovic Debels1 mth ago
- Self-Experimentation
How my hairs growth up! Thanks for watching.
- Yoga Perdana
- Yoga_Perdana
- 1 mth ago
- 32
- Self-Experimentation
Resveratrol -- value, dose, source?
There is controversy over resveratrol, and its advocates. What is the value of resveratrol as part of an age reversal supplement program? One highly visible individual recommends Resveratrol that is:…
- JohnnyAdamsmoderator
- Mission: Slow and Ultimately Reverse Biological Aging and Age Related Decline for More Years of Healthy Living
- JohnnyAdams
- 9 mths ago
- 20 replies
- 512
- Darian S1 mth ago
- Self-Experimentation
transplant patients
do transplant patients receive antiaging benefits or do they have negative effects on aging?
- curious
- curious
- 1 mth ago
- 20
- Self-Experimentation
mark t
I was wondering how you made your cream the 2mg in 4oz? 4oz of what? Thank you.
- curious
- curious
- 1 mth ago
- 18
- Self-Experimentation
Sources for NMN or NAD
it has been a while since anyone has posted sources for NMN. Anyone find any reliable sources at a reasonable price? Right now I buy from Amazon. Double Wood Supplements 30 grams in powder for $130.…
- ssny. sotero
- Marketing and Visual Impact Display Specialist
- sandra_sotero
- 2 mths ago
- 3 replies
- 135
- David H2 mths ago
- Self-Experimentation
Biological Age Test #4 in 2020: Getting Better or Getting Worse?
- michael lustgarten
- michael_lustgarten
- 2 mths ago
- 4 replies
- 159
- JGC2 mths ago
- Self-Experimentation
Can Senolytic drug cure Chronic kidney disease ?
Could you help to advise about senolytic drug and CKD ?
- PuRi
- PuRi
- 2 mths ago
- 2 replies
- 66
- hellscreamer2 mths ago
- Self-Experimentation
liposomal Fisetin
Wondering if anyone has heard of this? Supposedly much better absorption, but I would have no idea how to dose it... https://alivebynature.com/product/lsg-fisetin-liposomal-sublingual-gel/
- Robin Maisel
- Robin_Maisel
- 3 mths ago
- 2 replies
- 159
- Endless3 mths ago
- Self-Experimentation
Phosphatidylcholine IV
Ray Kurzweil is a fan of Phosphatidylcholine, and seems to be alone in this. Bill and others don't make much truck with it AFAIK. Ray has said he does both IV's and oral supplementation.…
- Danmoderator
- skipping my funeral
- dantheman
- 1 yr ago
- 19 replies
- 436
- 1
- garland3 mths ago
- Self-Experimentation
EPIGENETIC MUTATIONS, REVERSAL TO NORMAL
Does anybody know of any studies that suggest ways to revert epigenetic mutations back to normal? Direct or indirect methods. Thanks
- Andrew P K Yap
- Andrew_P_K_Yap
- 5 mths ago
- 11 replies
- 207
- Rhett Barret3 mths ago
- Self-Experimentation
Physician in the UK
Hello guys, I hope this is the good section for this. I am hoping to find a medical doctor in the UK that would be open to self experimentation for longevity purpose.…
- Raphael Nicolle
- Raphael_Nicolle
- 3 mths ago
- 26
- Self-Experimentation
Quantifying Phenotypic Age: Blood Test Measurement #3 in 2020
- michael lustgarten
- michael_lustgarten
- 3 mths ago
- 50
- Self-Experimentation
Biological Age = 32.75y, Chronological Age = 47y: First 2020 measurement
https://michaellustgarten.com/2020/02/14/biological-age-32-75y-chronological-age-47y-first-2020-measurement/
- michael lustgarten
- michael_lustgarten
- 8 mths ago
- 1 reply
- 220
- 1
- michael lustgarten3 mths ago
- Self-Experimentation

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