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Self-Experimentation

Share your personal story of trying a promising age-reversal protocol.

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Hello everyone, Many of us are self-experimenting in an effort to prolong our good health. In this sub-forum, we encourage you to share your own stories of what seems to be working for you.…
- Max Petomoderator
- Researcher, website & forum admin
- Maximus
- 1 yr ago
- 464
- 10
- Self-Experimentation
How to increase the bioavailability of Fisetin
I'm preparing to do a Fisetin senolytic experiment, but I've read on the article from Mayo Clinic ( https://linkinghub.elsevier.com/retrieve/pii/S2352396418303736 ) that the administration mode was…
- JPA
- JPA
- 6 mths ago
- 25 replies
- 580
- Danh Tranyesterday
- Self-Experimentation
dasatinib (Dasa-Pro)
'NOTICE: By the end of July IAS will be offering dasatinib (Dasa-Pro) in 12x 40mg double-scored tablets for $99.99 this will be uploaded to www.antiaging.…
- CSC
- CSC
- 13 days ago
- 1 reply
- 68
- 2
- BrianMDelaneymoderator13 days ago
- Self-Experimentation
Young plasma treatments in Tampa, Florida
My name is Howard Chipman MD and I have been treating patients with young plasma for anti-aging, dementia and other age related disorders for over a year with good results.…
- Dr. Chipman
- Dr_Chipman
- 1 yr ago
- 3 replies
- 439
- 4
- Daniel Stephenson13 days ago
- Self-Experimentation
Self-experimentation with variety of supplements and drugs
Greetings, I am 67, male, with type 2 diabetes, heart disease and high blood pressure. Current prescription drugs I take per doctor's order: 2000 mg metformin, 45 mg actos, 80 mg lipitor, 2.…
- Kim Mackey
- Kim_Mackey
- 2 wk ago
- 45
- Self-Experimentation
Rapamycin Cost
Let me clear some things up for people considering rapamycin (generic sirolimus). I am taking it and so are my dogs!! (I have a very open-minded vet who trusts my judgement.) Dr.…
- Rob8311
- Rob8311
- 1 yr ago
- 80 replies
- 2,714
- 5
- Van2 wk ago
- Self-Experimentation
Metformin: worth it? and what to expect
Hello all. I got my Doctor to give me a prescription for Metformin. I have read about its possible age-reversing effects, but I have also read about some possible significant side effects,…
- Jeff Bennion
- Jeff_Bennion
- 3 mths ago
- 33 replies
- 313
- are we there yet2 wk ago
- Self-Experimentation
Rapamycin self-experimentation
I've just begun a 10 week self-experimentation with RapaPro rapamycin. I'll be taking 5 mg once a week, which is roughly the dose that Dr. Alan Green recommends on the high side and seems to be…
- Tam
- Tam
- 1 mth ago
- 9 replies
- 122
- Larry3 wk ago
- Self-Experimentation
Just Ordered Rapamycin w/ No Prescription
When I was at Raadfest18, it was announced that there was a vendor in the Exhibition Hall from whom Rapamycin could be ordered at a good price. Later I found out exactly what vendor from someone…
- Mermaid
- Mermaid
- 7 mths ago
- 3 replies
- 243
- 3
- Richard Sapp3 wk ago
- Self-Experimentation
Possible negative response to oral NAD+
Hello, My wife and I (~50) have started a NAD+ regime in addition to rest of the other life long regime (vegan, exercise, other suppls). We started with 250mg (sourced from Life Extension),…
- Danmoderator
- skipping my funeral
- dantheman
- 9 mths ago
- 7 replies
- 402
- 2
- Richard Sapp4 wk ago
- Self-Experimentation
Fiestin to Clear Senescent Cells
Following studies with mice that showed significant senolytic clearance of senescent cells following large doses of the readily available flavenoid supplement Fisetin ,…
- JGC
- JGC
- 6 mths ago
- 90 replies
- 1,362
- 7
- Dan Nave1 mth ago
- Self-Experimentation
The purity of Lucidias-brand Dasatinib
Last year I obtained a 60-tablet bottle of 50 mg Lucidias-brand Dasatinib from BonHoa Pharmacy in New Deli, India, link https://www.bonhoa.com . It seems to be manufactured by Lucius Pharmaceuticals…
- JGC
- JGC
- 4 mths ago
- 12 replies
- 242
- 5
- Louise B Andrew1 mth ago
- Self-Experimentation
Phosphatidylcholine IV
Ray Kurzweil is a fan of Phosphatidylcholine, and seems to be alone in this. Bill and others don't make much truck with it AFAIK. Ray has said he does both IV's and oral supplementation.…
- Danmoderator
- skipping my funeral
- dantheman
- 3 mths ago
- 4 replies
- 135
- 1
- Tam1 mth ago
- Self-Experimentation
Rapamycin
I have done bio identical hormones for 3 1/2 months before I start Rapamycin. Do I take 5 mg once a week for 3 months and then take a month off and start again?
- Suzanne
- Suzanne
- 1 mth ago
- 5 replies
- 58
- Larry1 mth ago
- Self-Experimentation
NAD+ and Cancer
A post on Longecity.org four days ago entitled " NAD+ and Cancer " links to a recent Wistar Institute news release that cautions that boosting NAD+ levels in older animals leads to increased risk of…
- Bob S.
- Bob_S
- 4 mths ago
- 7 replies
- 137
- Paul Tozour1 mth ago
- Self-Experimentation
LDL-C reduction with diet and supplements (no statins)
Hi everyone, I recently came across some interesting videos about the optimal levels of LDL-C at the website, http://plantpositive.com/ . The author of the videos includes screenshots of the…
- Max Petomoderator
- Researcher, website & forum admin
- Maximus
- 1 yr ago
- 10 replies
- 252
- Paul Tozour1 mth ago
- Self-Experimentation
Did anyone experience acute inflammation after senolytics?
Hello, I have Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. It is a condition that involves chronic inflammation. I tried 3 days of high dose Fisetin the last 3 days (1000mg/day).…
- Phoenix
- phoenix
- 1 mth ago
- 3 replies
- 105
- Dan Nave1 mth ago
- Self-Experimentation
Ferulic acid
How to use ferulic acid and where to buy ferulic acid as supplement for oral use? My plan is to try Ferulic acid and EGCG (Green tea). My aim for this experiment is to see if this combo can clear…
- Staffan Olsson
- Staffan_Olsson
- 1 mth ago
- 29
- Self-Experimentation
Monitoring Senescent Cell Clearance with Cytokine Levels
Many of us have been attempting to clear our senescent cells with large senolytic doses of Fisetin and/or Dasatinib plus Quercetin. There have been many anecdotal reports of "feeling better" or…
- JGC
- JGC
- 4 mths ago
- 20 replies
- 256
- 1
- Dan Nave1 mth ago
- Self-Experimentation
Dasatinib
Hi Brian, On the website "SocietyforAgeReversal.org which is the same as rescueelders.org I think. You mentioned in the blog, "I'm taking a very quick break from the engaging presentations to report…
- Snowbird
- Snowbird
- 8 mths ago
- 30 replies
- 638
- RobH1 mth ago
- Self-Experimentation
Rapamycin Side Effect
Just read a recent addition to Dr. Green's site. I'll just post part of what he says. I don't get the impression he thinks it is a reason to stop treating, but important to be aware of.…
- Rob8311
- Rob8311
- 8 mths ago
- 67 replies
- 693
- 2
- Vincent Stona2 mths ago
- Self-Experimentation
ALA/ALC
Hi folks, glad to find a group and forum of other folks interested in helping themselves and others defeat aging. I'm going to do a number of posts on the results of my personal research and…
- Danmoderator
- skipping my funeral
- dantheman
- 1 yr ago
- 6 replies
- 224
- Dan Nave2 mths ago
- Self-Experimentation
You are invited to an online meeting Sat April 20, 2019
Dear Age Reversal Network Member, You are invited to attend the next Gerontology Research Group online/phone meeting. This no cost get-together is open to everyone,…
- JohnnyAdamsmoderator
- Mission: Slow and Ultimately Reverse Biological Aging and Age Related Decline for More Years of Healthy Living
- JohnnyAdams
- 2 mths ago
- 31
- 1
- Self-Experimentation
immediate release Metformin (irM) possible side effect: bladder/ prostate irritation
I started taking metformin about 1.5 months ago [2x500mg/day] and have noticed an increased urge to urinate. my bladder or prostate, possibly both, seems to react in a very bad way.…
- Cristian Lapusan
- Cristian_Lapusan
- 2 mths ago
- 35
- Self-Experimentation
Previous progress? Hope for the future!
I did say id share my progress of anti aging attempts. This is a 4 year gap between these pictures. In the first (I'm the one with the shades and tye die shirt) I had just turned 22 in the next…
- Red_Alchemist
- Ashley_Faul
- 3 mths ago
- 141
- 1
- Self-Experimentation
DMSO for Increased Flavenoid Solubility and Bioavailability?
The problem with the bio-delivery of senolytic flavenoids like Quercetin and Fisetin is that they are insoluble in water . Therefore, there is a good chance that if taken orally,…
- JGC
- JGC
- 4 mths ago
- 2 replies
- 102
- JGC3 mths ago
- Self-Experimentation

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