Sleep Quality DSIP
For those struggling with sleep quality, particularly waking up around midnight and being unable to return to deep sleep until early morning, I'd like to share my experience. I faced this issue, finding the nights long and tedious, and tried various remedies without success.
For the past couple years I have been using a peptide called deep-sleep-inducing-peptide (DSIP). Its a sub-q injection, and for me it has been remarkably effective.
Since using DSIP, I sleep through the night, only waking briefly for bathroom breaks before quickly falling back asleep. I've also noticed I'm dreaming nightly.
If you're experiencing similar sleep disruptions, you might consider DSIP as a potential solution. It's been a game-changer for my sleep quality
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Thanks for sharing this, Bruce. DSIP (Delta sleep-inducing peptide) has been studied for more than 40 years and is not commonly prescribed, but if your doctor approves and it works for you, that's great.
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Brian when I first saw mention of it, I read on the web many folks found it did not work so I was a bit sceptical ,I decided why not its a molecule the body makes . I also tried a DSIP fragment it worked as well.
If i run out or miss a dose, I am back to waking up at midnight no respite.
Anyhow if that helps anyone out I would be happy.
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Bruce B Do you have to do daily injections? Dosage? Thanks
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Van Van Yes, I use it each night around 8:30 -9:00 hit the hay around 10:00 if i decide to stay up it's no problem is does not seem to make you drowsy. Only time i miss is when I am not careful and run out. When I run out I get mad at myself. Honestly being able to sleep is worth the money , but I am going to try out a chinese supplier as the cost adds up.
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Bruce B Dosage?
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Van Hunter Williams puts dose and what one might stack with each compound at the end with his personal experience and efficacy.
I dose 160mcg (micro grams) just before bed because thats when I can reliably repeat each night.. My DSIP comes in 5mg viles for $35/ea from solution peptides. They still have a sale on for $32ea so I bought 5. 5mg/0.160 = 31 doses or approx $1/night. DSIP has a few other brain benefits to warrant continous use. I take SEMAX, 300mcg in the morning. Not noticable benefit for me. Again I take these things for the BDNF (etc) boosts.
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Van Limitless peptides sells nasal spray version of DSIP. I inject for lower cost. Like a diabetic daily multi injections can be learned. I agree a diabetic has no choice, peptide injecting isn't hard, even being optional.
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Van Van 300 micrograms works effectively for me.
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I combine DSIP with ipamorlan with CJC (search on youtube where peptide info is available. I buy dry peptide viles off the research sites; core peptides, limitless peptides, polaris peptides. learn off youtube how to reconstitude with whats called Bac water, buy pet needles off amazon. Cheapest and more effective to inject. But some peptides can be used nasally and you can buy those off these same sites ready to use but often 5x or more for a given month.
The Ipamorlan an HGH secretion nudging peptide seems to aid sleep and rest. I agree that DSIP is not knock out and some nights doesn't work. BUT further study; DSIP helps with brain garbage collection, lower inflammation. I will take DSIP forever along with other brain peptides: SEMAX with a touch of SELANK. Search in youtube. As a whole antiinflammation protocol that includes brain benefits the experts will add 2-3x/week BPC-157+TB-500. We are newer to peptides. There are cost limits and self injection frequency limits. This is a forever protocol like rapa but with a much higher month/yr cost AND hassel factor with daily, weekly injections. Its possible to runn out of cash on a burn rate basis and abililty to keep doing the injections. FWIW
i combine with 600mg Mg Glycinate and 1g of Glycine and some melatonin (your dose).
I also use this PEMF device for healing on knee/back and set to lower power and different frequency with paddles under my pillow: Flex Pulse G2.
=== side topic; muscle building, retention. Keeping this short
I(we) whole heartedly recommend the kaatsu C4 (or the newer model) for muscle growth/retention with at worst zero effort, just sit there work from home, driving even, doing computer work. I'm doing my legs as I type. Search on youtube; kaatsu C4 muscle growth. IMHO one of our best purchases. we are both stronger noticably at 71yo. I'm back to high school 40 pushups and hope to get back to HS 50. I wear the legs especially on the vibration plate which is in front of the head to toe LED panels. Kaatsu allows the ultimate multi tasking IMHO. I'm toooo lazy to go the Y, treadmill, weight lift for just lifting purpose. No way.
good luck, curt
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Curtis Smith
Doses at night before bed;
DSIP 160mcg
Ipamorlan/CJC 300mcg
Upon rising;
Semax 300mcg + selank 100mcg
Use this handy dilution, injection ml calculator;
https://primepeptides.co/pages/peptide-calculator
Buy; the peptide viles off above sites, BAC water off amazon, needles off amazon. For the back water its easiest to buy a few 3ml needles (big). For injecting peptides we have a range of 0.20 ml needles and 0.5ml. In a pinch I use 1.0ml needles.
Its a multi month learning curve. This is the BEST channel on youtube for peptide knowledge: Hunter Williams. Peptide Buddy
good luck, curt
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Curtis Smith
We gut sucked down the rabbit hole starting with Tirzepatide (a newer GLP-1). My wife at a lower 1.5mg /week. Now divided into 2 doses to lower side effects. I don't need to lose weight so I take very small dose for the brain/metabolic health at 0.5mg or less / week divided into 2 doses.
At 1-2mg / week buying from the research sites its possible for weight loss to cost just $100/mo total. Unfortunately the more peptide study, the more buying of more peptides and adding yet more organ rejuvination / boosting protocols; more buying more injecting... $1000/mo is easily possible at research materials prices. That would be un-imaginable $$$$ from a local Functional clinic!!!!
At some point we will find an equilibrium, move past beginners eagerness as the $$$ flies out the window... Its pretty hard to resist going after mitocontrial rejuvination, thymus / pituitary rejuvination, immune system boosting... its a pick what you think will give you the most benefit.
An observation from the peptide coaches; the worse off you are weight, metabolic healthy, athletic (not); the more you will feel a benefit from all of the above. The more athletic/healthy the less benefit. As you age; its not NO benefit even if healthy/athletic since you are experiencing severe pituitary/thymus fall off that is worth resisting by throwing $$ at them. We are 71 so $$$ at the thymus makes some sense. We aren't Bryan Johnson so our limits are being tested.
Then there's; bioregulators. Got this organ focused protocol in the fridge queued up. Also injected... ;( ;( ;(
A good thing; some of these protcols are periodic per year. Go for 20 days (blabla) 2x a year as an example.
At fairly good shape I feel a very noticable improvement from the kaatsu + PEMF device + the first thing in the AM HGH boosters; Tesamorlan + Ipamorlan / CJC, 2x a week. I did memtion ipamorlan/CJC at bedtime as well.
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Curtis Smith Have you ever tried using DAC (Drug Affinity Complex) with Ipamorlan/CJC? I saw that term when asking ChatGPT questions about Ipamorlan/CJC. It's a new acronym to me, but you may know more about it. ChatGPT says it extends half-life from a few hours to several days, making injections less frequent, therefore, less costly.
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Bruce B, I sent you a private message, but I'll ask here too. Do you mind revealing the different sources you've used for DSIP and your opinions about each? Thanks.
