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Self-Experimentation

Share your story of trying or designing a promising age-reversal protocol.

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My anti-aging journey - How long for the collagen?
Family and I will be addressing the 9 hallmarks of aging, including genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, deregulated nutrient-sensing,…
- Luke Duran
- Luke_Duran
- 1 yr ago
- 4replies
- 140
- 1
- Last replyLuke Duran1 yr ago
- Self-Experimentation
Cholesterol Esters: Underrated Metabolites That Are Associated With Youth And Survival
https://www.youtube.com/watch?v=KhKYKvpKfJ4
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 25
- Self-Experimentation
Astaxanthin - A proven life extending supplement?
New and unpublished data from the ITP (Interventions Testing Program) show that Astaxanthin is one of few substances that show life extending effects, At least when tested rigorously in the programs…
- Staffan Olsson
- Staffan_Olsson
- 2 yrs ago
- 5replies
- 573
- 1
- Last replyMoonlitnight1 yr ago
- Self-Experimentation
Did Niacin (Or NAD Being Too High) Mess Up The Epigenetic Pace Of Aging?
https://www.youtube.com/watch?v=E1vV_iu41fk
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 39
- Self-Experimentation
Supplemental Tryptophan: Impact on NAD?
https://www.youtube.com/watch?v=8FcnNfRo--w
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 21
- Self-Experimentation
Did Tryptophan And/Or Serine Mess Up Blood Biomarkers? (Blood Test #5 in 2023 Analysis)
https://www.youtube.com/watch?v=GQXd-iimf1A
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 12
- Self-Experimentation
Uremic Metabolites: Kidney Function Biomarkers
https://www.youtube.com/watch?v=ZEG9idULZc0&t=1s
- michael lustgarten
- michael_lustgarten
- updated 1 yr ago
- 12
- Self-Experimentation
Tryptophan + Niacin: No Additive Effect On NAD, Relative To Niacin Alone
https://www.youtube.com/watch?v=7JH_iVMzZD4
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 17
- Self-Experimentation
Serine + Vitamin B6: Did It Reduce Homocysteine? (Test #1)
https://www.youtube.com/watch?v=K80je_l2oCg
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 1reply
- 32
- Last replymichael lustgarten1 yr ago
- Self-Experimentation
Circulating Levels Of Omega-3 Fatty Acids (EPA, DHA) Decline During Aging
https://www.youtube.com/watch?v=VoGw8NCAR7I
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 28
- Self-Experimentation
Rapamycin - progress so far
Hi all, About me: I'm 46 y.o. medical doctor based in Europe and started taking weekly rapamycin 4 months ago. I go to the gym regularly and am in average physical condition for a guy of my age.…
- Diamond Tree
- Diamond_Tree
- updated 3 yrs ago
- 86replies
- 3374
- 7
- Last replyJonas Huberman1 yr ago
- Self-Experimentation
Niacin Increases NAD (Test Results)
https://www.youtube.com/watch?v=7_CY7LrFPwU
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 30
- Self-Experimentation
16 - 20y Younger Biological Age: Supplements, Diet (Blood Test #4 in 2023)
https://www.youtube.com/watch?v=51sSUu0PabU
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 75
- 1
- Self-Experimentation
35% Increase For Heart Rate Variability Since 2018
https://www.youtube.com/watch?v=MFIvRjec46A
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 1reply
- 51
- Last replymichael lustgarten1 yr ago
- Self-Experimentation
Metabolite Ratios As An Index Of Oxidative Stress
https://www.youtube.com/watch?v=CdfxQv-Pejw
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 8
- 1
- Self-Experimentation
Paul's self experiment II
My original thread was hi-jacked so starting another Still taking rapamycin. Experimented with GDF11 and will take blood tests in Jan to see if it has had an effect Looking into peptides.…
- Paul Beauchemin
- Paul_Beauchemin
- 3 yrs ago
- 2replies
- 299
- 1
- Last replyJay Orman1 yr ago
- Self-Experimentation
Grape Seed Proanthocyanidins Increase NAD
https://www.youtube.com/watch?v=KsFKIl3JtP0
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 34
- Self-Experimentation
Possible negative response to oral NAD+
Hello, My wife and I (~50) have started a NAD+ regime in addition to rest of the other life long regime (vegan, exercise, other suppls). We started with 250mg (sourced from Life Extension),…
- Danmoderator
- skipping my funeral
- dantheman
- 6 yrs ago
- 18replies
- 1255
- 2
- Last replyJay Orman1 yr ago
- Self-Experimentation
Telomere Length Test #6: Correlations With Diet
https://www.youtube.com/watch?v=gWeht1QdpLc
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 20
- Self-Experimentation
Quality of various NMN products
So following the work of Dr David Sinclair ....about 5 months ago I added NMN to my daily supplement regime, taking 500mg on an empty stomach every morning about 7am.…
- Donkey Hotie
- Donkey_Hotie
- 1 yr ago
- 4replies
- 74
- 1
- Last replyCurtis Smith1 yr ago
- Self-Experimentation
Anyone actually experience marked increased energy from NMN?
It's been 2 years now - sublingual. Nothing. I'm ready to throw it in the box with the resveratrol and rapamycin. Please leave your experiences and types/doses as well as how you can differentiate…
- Michael
- Michael.1
- 3 yrs ago
- 139replies
- 2983
- Last replychuck stanley1 yr ago
- Self-Experimentation
Rapamycin thanks to Dr.Garcia, Significantly improves Lymphocytes
In January I went to see Dr. Garcia in Las Vegas who I regularly see for PRP. I explain to him how my lymphocytes including cd4 which had dropped to 325 way below normal and asked about taking…
- John Mcgough
- John_Mcgough
- 4 yrs ago
- 5replies
- 195
- 1
- Last replyJohn Mcgough1 yr ago
- Self-Experimentation
Rapamycin in humans
I'm cautious on pharmaceuticals but am considering Rapamycin. Downsides are cost, difficulty to source and potential side effects (some people suffer from stomach issues IIRC).…
- Danmoderator
- skipping my funeral
- dantheman
- 6 yrs ago
- 41replies
- 990
- 1
- Last replyAlex1 yr ago
- Self-Experimentation
Paul's self experimentation
I inadvertently started on this 5 years ago when I started taking Metformin. Was diagnosed with a Gleason 6 prostate cancer. Docs didn't want to treat just monitor.…
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- 66replies
- 1324
- 3
- Last replyAlex1 yr ago
- Self-Experimentation
Rilmenidine 19% life extension calorie memic not sold in us
- are we there yet
- are_we_there_yet
- 1 yr ago
- 59
- 1
- Self-Experimentation

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