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Senolytics Discussion

Discussions about senolytics for the removal of senescent cells.

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Sources of dasatinib
Hello everyone, We’ve received reports from Age Reversal Network members about lower-cost sources of dasatinib. This post is intended to aggregate this information into a single forum post for easy…
- Max Petomoderator
- Researcher, website & forum admin
- Maximus
- 1 mth ago
- 11 replies
- 293
- 3
- angie4life2 wk ago
- Senolytics Discussion
Introduction to senolytics
Hi everyone, The term " senolytics " refers to compounds that selectively induce cell death in senescent cells. Senescent cells are cells whose metabolism has gone awry for one reason or another,…
- Max Petomoderator
- Researcher, website & forum admin
- Maximus
- 1 yr ago
- 19 replies
- 568
- 2
- Dan Nave3 mths ago
- Senolytics Discussion
fisetin phytosome preparation
curcumin phytosome was prepared from curcumin , phosphatidylcholine in methylene chlride,acta pharm v65 (2015) P 285- 297. May be fisetin phytosome could be prepared likewise?
- leon golabou
- leon_golabou
- 11 days ago
- 13
- Senolytics Discussion
Azithromycin (Zithromax) as senolytic; a note of caution
This is the problem with "cell studies." The authors who found this result decided to look at what they called a "low dose" of azithromycin (AZM) on cells.…
- Steve Harris
- Steve_Harris
- 8 mths ago
- 4 replies
- 450
- 3
- Kirill Pershin1 mth ago
- Senolytics Discussion
Fisetin ( + quercitin)
Among flavonoids, fisetin appears to be an effective senolytic: https://www.fightaging.org/archives/2018/10/animal-data-shows-fisetin-to-be-a-surprisingly-effective-senolytic/ "Fisetin appears about…
- cacarr
- cacarr
- 10 mths ago
- 35 replies
- 950
- 4
- Staffan Olsson1 mth ago
- Senolytics Discussion
AB263 Navitoclax
This is very interesting https://www.adooq.com/abt-263-navitoclax.html The 10ml dosing is in 1ml of DMSO, taken orally. We need to look at this further!
- BobM
- BobM
- 2 mths ago
- 2 replies
- 37
- cacarr1 mth ago
- Senolytics Discussion
Fisetin Dosage Calculations
Hi everyone! I'm new to this forum, but I've been observing from the sidelines and learning a lot from your posts, so thank you! I found this forum after becoming interested in fisetin as a…
- Ash P
- Ash_P
- 2 mths ago
- 1 reply
- 73
- Steve Harris1 mth ago
- Senolytics Discussion
Details of dasatinib + quercetin study
What were the dosages of dasatinib and quercetin used for this study? What kind of quercetin was used? Any issues or side effects noted so far?
- Ozone8
- Ozone8
- 1 yr ago
- 68 replies
- 1,209
- 2
- peter bradley1 mth ago
- Senolytics Discussion
The Initial D+Q Study
I became curious as to just how it was determined that the combination of Dasatinib and Quercetin in a 1:10 combination was an effective senolytic treatment.…
- JGC
- JGC
- 7 mths ago
- 156
- 3
- Senolytics Discussion

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