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Senolytics Discussion

Discussions about senolytics for the removal of senescent cells.

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New Anti-Aging clinic in Georgia.
I noticed a new clinic has opened in the state of Georgia that prescribes metformin, rapamycin, and dasatinib. Mikhail Blagosklonney tweeted the link this morning.…
- Larry
- Larry.1
- 4 yrs ago
- 113
- Senolytics Discussion
Sulfuraphane
On Dr Kaufmann’s website, it states that sulfuraphane protects cells from apoptosis and senescence. This would seem to work against senolytics. Does anyone take sulfuraphane and if so do you stop…
- Karl
- Karl.1
- 5 yrs ago
- 1reply
- 209
- 1
- Last replyStaffan Olsson5 yrs ago
- Senolytics Discussion
Blocking negative effects of senescence in human skin fibroblasts with a plant extract
I find this very interesting. And people that focus on preventing senescence and the aging of their skin might be extra interested in how we can interpretate the research above.…
- Staffan Olsson
- Staffan_Olsson
- 5 yrs ago
- 2replies
- 202
- 1
- Last replyBobM5 yrs ago
- Senolytics Discussion
Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin
https://www.ebiomedicine.com/article/S2352-3964(19)30591-2/fulltext
- Larry
- Larry.1
- 5 yrs ago
- 2replies
- 161
- Last replyLarry5 yrs ago
- Senolytics Discussion
fisetin phytosome preparation
curcumin phytosome was prepared from curcumin , phosphatidylcholine in methylene chlride,acta pharm v65 (2015) P 285- 297. May be fisetin phytosome could be prepared likewise?
- leon golabou
- leon_golabou
- 5 yrs ago
- 180
- Senolytics Discussion
AB263 Navitoclax
This is very interesting https://www.adooq.com/abt-263-navitoclax.html The 10ml dosing is in 1ml of DMSO, taken orally. We need to look at this further!
- BobM
- BobM
- 5 yrs ago
- 2replies
- 124
- Last replycacarr5 yrs ago
- Senolytics Discussion
Fisetin Dosage Calculations
Hi everyone! I'm new to this forum, but I've been observing from the sidelines and learning a lot from your posts, so thank you! I found this forum after becoming interested in fisetin as a…
- Ash P
- Ash_P
- updated 5 yrs ago
- 1reply
- 1102
- Last replySteve Harris5 yrs ago
- Senolytics Discussion
The Initial D+Q Study
I became curious as to just how it was determined that the combination of Dasatinib and Quercetin in a 1:10 combination was an effective senolytic treatment.…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- 327
- 6
- Senolytics Discussion

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Discussions about senolytics for the removal of senescent cells.

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