Sulfuraphane

On Dr Kaufmann’s website, it states that sulfuraphane protects cells from apoptosis and senescence. This would seem to work against senolytics. Does anyone take sulfuraphane and if so do you stop taking it while doing a senolytic treatment?

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  •  Interesting question. I don't think there is a clear answer to it.

     

    I can say that some senolytic substances and the apoptosis they generate is depending on ROS (reactive oxidant species). And ROS acitivity is inhibited by antioxidants. So before a senolytic sessions I stay away from most supplements with strong antioxidant effect. With this reasoning anything that could stop apoptosis of senescent cells should be avoided.

     

    I guess we are left to trust our own guesswork (based on the procedural facts we know). which means that I probably should stay away from getting sulfuraphane into my cells during a senolytic treatment. 

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