1reply
-
Interesting question. I don't think there is a clear answer to it.
I can say that some senolytic substances and the apoptosis they generate is depending on ROS (reactive oxidant species). And ROS acitivity is inhibited by antioxidants. So before a senolytic sessions I stay away from most supplements with strong antioxidant effect. With this reasoning anything that could stop apoptosis of senescent cells should be avoided.
I guess we are left to trust our own guesswork (based on the procedural facts we know). which means that I probably should stay away from getting sulfuraphane into my cells during a senolytic treatment.