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Re: Has anyone tried taking fietin as a suppository?
@Michael_123 I am sorry but I can only speculate about how the anal route differs from the oral route. When it comes to using suppositories to aid substances to reach reach the prostate, colon, etc.…
Staffan Olsson
Staffan_Olsson
7 mths ago
Senolytics Discussion
Reported - view
Re: Intermittent dosing
You raise an important aspect on supplementation. When we take pharmaceuticals we know that the risk of negative interactions (side effects) go up with the number of medicines we take.…
Staffan Olsson
Staffan_Olsson
8 mths ago
General Discussion
Reported - view
Re: Glycine + N-Acetyl Cysteine Supplementation Increases Lifespan
Is there a treshold effect when using NAC on compromised levels of glutathione and for inhibition of mTOR? Since some persons (like Dr brad Stanfield) promote the view that the amount of NAC-Glycine…
Staffan Olsson
Staffan_Olsson
9 mths ago
1
General Discussion
Reported - view
Re: Norvaline
@chuck stanley Norvaline has several interesting effects that is related to antiaging and to disease prevention. And yes I have also seen what is written in medical express.…
Staffan Olsson
Staffan_Olsson
9 mths ago
1
Questions & Answers
Reported - view
Norvaline
Does anybody here have experience from the use of Norvaline? in that case did you notice any cognitive effects? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557086/
Staffan Olsson
Staffan_Olsson
9 mths ago
2
replies
45
Questions & Answers
Answered
Answered
Re: Webinars - Lifespan - Healthpan etc
Here is a link to his fascinating presentation, quite short but comprehensive about the ongoing ITP research. Drugs that slow ageing in mice | Prof Richard A.…
Staffan Olsson
Staffan_Olsson
9 mths ago
1
General Discussion
Reported - view
Webinars - Lifespan - Healthpan etc
You can register here to participate on webinars from Singapore. Next up is Prof Richard MIller, Leader of the ITP lab. The host of the week is Brian Kennedy.…
Staffan Olsson
Staffan_Olsson
10 mths ago
1
reply
36
General Discussion
Re: Taurine in general health as well as in mitochondrial health
@Staffan Olsson @michael lustgarten Taurine is used in many PWO products. In my self-experimentation with taurine I have evaluated its effect on exercise capacity.…
Staffan Olsson
Staffan_Olsson
10 mths ago
1
Ideas
Reported - view
Re: Photo evidence that the experiment is working
@Andrew P K Yap Thank you for publicly documenting your journey with pictures. I wonder how you would describe your experience with words? What are the biological and psychological differences you…
Staffan Olsson
Staffan_Olsson
10 mths ago
Self-Experimentation
Reported - view
Re: Taurine in general health as well as in mitochondrial health
Three papers focusing on Taurine and its potential effects on health and longevity. The Role of Taurine in Mitochondria Health: More Than Just an Antioxidant - PMC (nih.…
Staffan Olsson
Staffan_Olsson
10 mths ago
Ideas
Reported - view
0
Taurine in general health as well as in mitochondrial health
Taurine is a supplement that deserve more attention from the antiaging community, and I wish the ITP program could test Taurine’s effects on aging. Taurine has many interesting effects.…
Staffan Olsson
Staffan_Olsson
10 mths ago
4
replies
102
Ideas
2022 ARDD videos now available
The videos from this years (2022) "Aging research and drug discovery meeting" is now available. Some really good ones. https://www.youtube.com/channel/UClOnplI2mzpJlwdX3vlOMJA/videos
Staffan Olsson
Staffan_Olsson
11 mths ago
33
1
General Discussion
Re: Introduction to senolytics
First link: Here is is a very informative update about senescence and the potential of senolytic therapies. By Prof James Kirkland. He starts his talk at 45 min and 50 sec.…
Staffan Olsson
Staffan_Olsson
11 mths ago
Senolytics Discussion
Reported - view
Re: Fisetin to Clear Senescent Cells
@Moonlitnight I really appreciate being able to buy supplements in powder form from a source that do third party testing. (Yesterday I received my first curcumin BCM-95 from them.…
Staffan Olsson
Staffan_Olsson
1 yr ago
1
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@Moonlitnight I have bought twice from this source. (Spermidine and apigenin in powderform). They are shipping globally. So far I am satiesfied with the quality.…
Staffan Olsson
Staffan_Olsson
1 yr ago
1
Self-Experimentation
Reported - view
Re: Deprenyl (Selegiline) as a Longevity Drug?
Deprenyl has a long history in the life extension community. (Credit goes to Mr Faloon). https://www.lifeextension.com/magazine/2016/2/the-most-sought-after-anti-aging-drug https://www.lifeextension.…
Staffan Olsson
Staffan_Olsson
1 yr ago
1
Self-Experimentation
Reported - view
Re: Exercise section
I agree on the perspective that the muscular system is a secretory organ that constantly secrete molecules to the rest of the body. Muscles are highly metabolic, easily targeted,…
Staffan Olsson
Staffan_Olsson
1 yr ago
2
Questions & Answers
Reported - view
Re: Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin inhumans?
@chuck stanley I take the spermidine ( and apigenin) on a small measuring spoon and then I put it straight into my mouth and I also have some water water with it.
Staffan Olsson
Staffan_Olsson
1 yr ago
1
General Discussion
Reported - view
Re: Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin inhumans?
@Fred Cloud I use this brand Spermidine - Pure NMN and Resveratrol anti-aging Supplements (hansensupplements.com) (Pure spermidine 5% and cellulose 95%).…
Staffan Olsson
Staffan_Olsson
1 yr ago
1
General Discussion
Reported - view
Re: Fisetin to Clear Senescent Cells
@Staffan Olsson This time I did not experience the same effects as I did when I had my first couple of senolytic treatments with fisetin. I still feel good and strong a few days after the session.…
Staffan Olsson
Staffan_Olsson
1 yr ago
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@Jack Black Yesterday I had 40 mg/kg Fisetin Dr’s best brand. And this morning (after approx 15 hours) I had another dose of 40 mg/kg Fisetin . 3 hours after the fisetin I had a large dose of…
Staffan Olsson
Staffan_Olsson
1 yr ago
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@Jack Black Thank you for your report. which brand of fisetin did you use? I have observed different effects from Dr's best fisetin and the life extension brand Bio -fisetin.…
Staffan Olsson
Staffan_Olsson
1 yr ago
Self-Experimentation
Reported - view
Re: D+Q+F+P+L+G+GLA: A New Senolytic Cocktail
@JGC if the prostate is causing discomfort from BPH/prostatitis PL might (anecdotally) reduce the discomfort.
Staffan Olsson
Staffan_Olsson
1 yr ago
Self-Experimentation
Reported - view
Re: D+Q+F+P+L+G+GLA: A New Senolytic Cocktail
Geroprotect Autophagy Renew is an interesting product. This since it is one of the few products that contain piperlongumine. I think it is a substance that could use at lot more attention since it…
Staffan Olsson
Staffan_Olsson
1 yr ago
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@Juan Daw I think it is relevant to mention that Maqui Berry - Delphinidine has shown some distinct effects on fasting and Postprandial Glycemia and Insulinemia.…
Staffan Olsson
Staffan_Olsson
1 yr ago
Self-Experimentation
Reported - view
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Staffan Olsson
Staffan_Olsson
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