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Re: Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin inhumans?
@Jack Black Thank you for your feedback on spermidine. Yes, I have noticed a minor hair rejuvenation. A few days ago my daughter said “I see more hair growing on your head”.…
Staffan Olsson
Staffan_Olsson
9 days ago
1
General Discussion
Reported - view
Re: Fisetin to Clear Senescent Cells
@Aaron When I take large doses of Fisetin I feel a weakness in thighs and I easily get sore muscle after extercise. When I have large amounts of dried Parsley (rich in apigenin) it has a sedative…
Staffan Olsson
Staffan_Olsson
3 wk ago
1
Self-Experimentation
Reported - view
Re: Kaufmannprotocol
@David H I find that spermidine makes me sleepy and that it improvs my sleep. So I take it with my evening meal.
Staffan Olsson
Staffan_Olsson
2 mths ago
General Discussion
Reported - view
Re: Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin inhumans?
@David H Now I have been eating spermidine capsules for approx 6 weeks. Brand - Aenutri 1 mg/day. I am 58. If someone decide to start with spermadine, I would suggest to take pictures of hair and…
Staffan Olsson
Staffan_Olsson
3 mths ago
General Discussion
Reported - view
Re: Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin inhumans?
Thank you David. I think spermidine needs a thread on its own. I started with spermidine one week ago so it is too early to say anything about it besides the acute effects.…
Staffan Olsson
Staffan_Olsson
4 mths ago
General Discussion
Reported - view
Re: Fisetin to Clear Senescent Cells
@Staffan Olsson regarding the above mentioned product it is important to read their webpage. The research that has been done on sublingual liposomal fisetin is done by comparing administration of…
Staffan Olsson
Staffan_Olsson
5 mths ago
2
Self-Experimentation
Reported - view
Re: Dr. Sinclair claims he reversed his Horvath clock by 29 years!
@Curtis Smith Rejuvant use Calcium Alpha-ketoglutarate (Ca-AKG). I have not tried that supplement yet. But the Ca-AKG effect made me curious. I have tried L-arginine-alfa-ketoglutarate (AAKG) 4 gr…
Staffan Olsson
Staffan_Olsson
5 mths ago
General Discussion
Reported - view
Re: Fisetin to Clear Senescent Cells
I have made a similar experience. Based on nothing but my own personal experience I prefer to take Fisetin on empty stomach in the morning (after having taken some black pepper or piper longum…
Staffan Olsson
Staffan_Olsson
5 mths ago
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@garland Sounds like strong effect. Did you take fisetin alone or did you take it with quercetin?
Staffan Olsson
Staffan_Olsson
6 mths ago
1
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@garland Metabolism is a very complex process and at this stage it is not possible at this stage to say something certain about how fisetin and quercetin influence each others biological actions…
Staffan Olsson
Staffan_Olsson
6 mths ago
Self-Experimentation
Reported - view
Re: Glucosamine instead of Metformin and Rapamycin?
I write this post because I have read that AMPK activation could possibly be detrimental in neurological some diseases. (not knowing if it is correlation or a possible causation).…
Staffan Olsson
Staffan_Olsson
6 mths ago
AMPK Activation
Reported - view
Re: Fisetin to Clear Senescent Cells
@Dan Nave Hi! I have this link to a paper from 2010 that discuss how to Improv the oral bioavailability of beneficial polyphenols through designed synergies.…
Staffan Olsson
Staffan_Olsson
6 mths ago
Self-Experimentation
Reported - view
Re: Rejuvant?
@Paul Beauchemin Thank you for the links. The you tube interview was great. I think they don't recommend taking AKG with multivitamins since the combination might cancel out each other's positive…
Staffan Olsson
Staffan_Olsson
7 mths ago
General Discussion
Reported - view
Re: Paul's self experimentation
@Peter H. Howe Thank you for the information. I did not know that metformin can decrease T.
Staffan Olsson
Staffan_Olsson
7 mths ago
Self-Experimentation
Reported - view
Re: Rejuvant?
@Iðunn AS far as know they published it yesterday in cell metabolism. But not the full paper. And it is not a free version. Cell-metabolism Short Article| Volume 32, ISSUE 3 , P447-456.…
Staffan Olsson
Staffan_Olsson
7 mths ago
General Discussion
Reported - view
Re: Rejuvant?
@Iðunn This is the full text. https://www.biorxiv.org/content/10.1101/779157v1.full.pdf
Staffan Olsson
Staffan_Olsson
7 mths ago
General Discussion
Reported - view
Re: Rejuvant?
@David H Thank you David! Much appreciated.
Staffan Olsson
Staffan_Olsson
7 mths ago
General Discussion
Reported - view
Re: Rejuvant?
@Paul Beauchemin I found this paper about CaAKG. Calcium-Alpha Ketoglutrate is to find. Have someone else here had better luck? https://www.sciencedirect.…
Staffan Olsson
Staffan_Olsson
7 mths ago
1
General Discussion
Reported - view
Re: Treatment for Reducing Arterial Plaque and Imflammatory Cells:
@Peter H. Howe Thank you for the reference to World of molecules. it indicate that fisetin might useful in more ways than acting as a senolytic compound.
Staffan Olsson
Staffan_Olsson
7 mths ago
General Discussion
Reported - view
Re: Treatment for Reducing Arterial Plaque and Imflammatory Cells:
@Peter H. Howe Peter. I am happy you find Fisetin useful. I do to. some seem to have the idea that you can benefit from fisetin in different ways. One way is to use the procedures that most of us…
Staffan Olsson
Staffan_Olsson
7 mths ago
1
General Discussion
Reported - view
Re: Treatment for Reducing Arterial Plaque and Imflammatory Cells:
@Peter H. Howe Peter, I am very curious about how people use fisetin. And nice to hear that fisetin works well for you. Can you share how you use fisetint?…
Staffan Olsson
Staffan_Olsson
7 mths ago
1
General Discussion
Reported - view
Re: Treatment for Reducing Arterial Plaque and Imflammatory Cells:
@BobM Here is another perspective on how to reverse atherosclerosis. There is research aiming at reversing athrerosclerosis by resetting the microbiome. They have done it successfully on rats.…
Staffan Olsson
Staffan_Olsson
9 mths ago
General Discussion
Reported - view
Re: Treatment for Reducing Arterial Plaque and Imflammatory Cells:
@Fred Cloud Thank you Fred. I do other interventions for now, but any progression in the field of plaque reduction is very interesting to me.
Staffan Olsson
Staffan_Olsson
9 mths ago
1
General Discussion
Reported - view
Re: Treatment for Reducing Arterial Plaque and Imflammatory Cells:
@Fred Cloud Thank you for your response. I wonder if you can share your experiences of edta chelations. After 75 chelations your personal experience and the health benefits of the treatment is very…
Staffan Olsson
Staffan_Olsson
9 mths ago
General Discussion
Reported - view
Re: Treatment for Reducing Arterial Plaque and Imflammatory Cells:
I have no personal experience of it, but one therapy that some people say can reduce plaque is Vascular Rejuvenation using EDTA. Here is a link: https://brain.forever-healthy.…
Staffan Olsson
Staffan_Olsson
9 mths ago
General Discussion
Reported - view
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Staffan Olsson
Staffan_Olsson
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