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Re: Senolytic guru Dr De Keizer says quercetin is useless? Certainly this study shows Quercetin to be rather wimpy as a senolytic. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197652/#!po=39.3617
- Karl
- Karl.1
- 1 mth ago
- Senolytics Discussion
- Reported - view
Re: Promises and more promises Why is YouTube your source of information?
- Karl
- Karl.1
- 1 mth ago
- General Discussion
- Reported - view
Re: Rapamycin doctors in San Diego? The physician directory lists 3.
- Karl
- Karl.1
- 1 mth ago
- Rapamycin Discussion
- Reported - view
Re: Fisetin to Clear Senescent Cells @Robert Olin I don’t mean to rain on your parade. I’m glad you’re here and getting involved in senolytics. There is great potential to slow or reverse aging.…
- Karl
- Karl.1
- 2 mths ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Robert Olin you are making the assumption that more is better?
- Karl
- Karl.1
- 2 mths ago
- Self-Experimentation
- Reported - view
Re: Vitamin C and the Corona Virus @John Tillson could not find any completed scientific randomized blinded study showing vitamin c treats Covid. Hopefully that will change.
- Karl
- Karl.1
- 2 mths ago
- Questions & Answers
- Reported - view
Re: Vitamin C and the Corona Virus @John Tillson you’d have to point out that evidence because I haven’t seen anything significant.
- Karl
- Karl.1
- 2 mths ago
- Questions & Answers
- Reported - view
Re: Vitamin C and the Corona Virus Unfortunately the results of studies of vitamin C in sepsis have not shown much success. https://pulmccm.org/critical-care-review/vitamin-c-didnt-improve-septic-shock-in-vitamins-trial/
- Karl
- Karl.1
- 2 mths ago
- Questions & Answers
- Reported - view
Re: Senolytics @Edward Meininger I have only taken D&Q once, but it kicked my ass. Nausea started at 2 hrs and last for about 10 hrs with vomiting at the end. Body aches and fatigue for several hrs,…
- Karl
- Karl.1
- 2 mths ago
- Self-Experimentation
- Reported - view
Re: Sources of dasatinib @Pablo Reinaldos López Dasatinib has a half life of 3-5 hrs.
- Karl
- Karl.1
- 2 mths ago
- Senolytics Discussion
- Reported - view
Re: Preparations for self-treating COVID-19 @Florin now we need a double blind prospective study. Would be nice if one arm of the study did not include Azithromycin.
- Karl
- Karl.1
- 2 mths ago
- Self-Experimentation
- Reported - view
Re: Senolytics @Dan Nave great find. Unfortunately sounds like this would become a patented drug and fetch a high price?
- Karl
- Karl.1
- 3 mths ago
- Self-Experimentation
- Reported - view
Re: rapamycin, trametinib, lithium combo Nice find Jeff Anyone know how they came up with Trametinib?
- Karl
- Karl.1
- 3 mths ago
- Assessing Biological Age
- Reported - view
Re: Azithromycin (Zithromax) as senolytic; a note of caution @uzoma iwuagwu interesting data. Do you have a link?
- Karl
- Karl.1
- 3 mths ago
- Senolytics Discussion
- Reported - view
Re: Preparations for self-treating COVID-19 3 studies this week in France, China, and Brazil show no benefit from Hydroxychloroquine in treating Covid. Hopefully more studies to come.
- Karl
- Karl.1
- 3 mths ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) My wife and I have done two fisetin runs with no noticeable effects. D&Q next.
- Karl
- Karl.1
- 3 mths ago
- Senolytics Discussion
- Reported - view
Re: Preparations for self-treating COVID-19 One more public service announcement. If you decide to get these medicines to take or have around in case, be aware that chloroquine falls in the category that toxicologists refer to as “one pill…
- Karl
- Karl.1
- 3 mths ago
- Self-Experimentation
- Reported - view
Re: Preparations for self-treating COVID-19 @Florin don’t really care to argue with you if your source of medical information is local abc new. I would ask you to look at that story to see if it really passes any scientific review.
- Karl
- Karl.1
- 3 mths ago
- Self-Experimentation
- Reported - view
Re: Events Thanks for the info.
- Karl
- Karl.1
- 4 mths ago
- General Discussion
- Reported - view
Re: Preparations for self-treating COVID-19 A lot of interesting discussion. Unfortunately its like talking with anti-vaxxers. People have made up their minds and not changing. My only purpose in posting here was to warn people that they may…
- Karl
- Karl.1
- 4 mths ago
- Self-Experimentation
- Reported - view
Re: Berberine @Joe smith Interesting article. I don't need the lipid lowering effect. My concern is why take a diabetic medicine if Berberine has the AMPK effect that is desired?
- Karl
- Karl.1
- 4 mths ago
- AMPK Activation
- Reported - view
Re: Preparations for self-treating COVID-19 @Paul Beauchemin when you use the phrase “with all due respect “, it usually means you don’t respect. Thanks for the disrespect and stereotyping me. I hope nobody does the same to you.…
- Karl
- Karl.1
- 4 mths ago
- Self-Experimentation
- Reported - view
Re: Preparations for self-treating COVID-19 @Paul Beauchemin thanks for letting me know what’s wrong with all doctors.
- Karl
- Karl.1
- 4 mths ago
- Self-Experimentation
- Reported - view
Re: Preparations for self-treating COVID-19 An interesting article: Interaction of Metformin and Hydroxychloroquine https://www.biorxiv.org/content/10.1101/2020.03.31.018556v1
- Karl
- Karl.1
- 4 mths ago
- 1
- Self-Experimentation
- Reported - view
Re: Preparations for self-treating COVID-19 @Paul Beauchemin as a physician I understand every drug has side effects. And I’m glad your wife has done well on Plaquenil. But Plaqnenil is a far more dangerous drug than Tylenol.
- Karl
- Karl.1
- 4 mths ago
- Self-Experimentation
- Reported - view

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