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Re: Sources of dasatinib
Does anyone know where Dr Green's patient's get their Dasatinib?
- Karl.1
- 5 yrs ago
- Senolytics Discussion
- Reported - view
Human Studies

If you are aware of Human Longevity studies, could you post here? Seems like 99.9% of the data that is talked about in longevity is based on mouse, worm,…
- Karl.1
- 5 yrs ago
- 27
- Questions & Answers
Re: Cycling Rapamycin with NAD+ Precursors
@Mark Thimineur How long after initial start of Rapamycin, did you notice the positive effects?
- Karl.1
- 5 yrs ago
- 2
- Rapamycin Discussion
- Reported - view
Re: Metformin dosage
As David has noted there are doses recommended, and I suspect these doses are all based on the standard doses for diabetes. I doubt any studies have been done comparing various doses and their…
- Karl.1
- 5 yrs ago
- 1
- AMPK Activation
- Reported - view
Re: The "Reprogramming" of Aging Cells
Probably why so many drugs and supplements show evidence of minor life extension.
- Karl.1
- 5 yrs ago
- General Discussion
- Reported - view
Re: Rapamycin self-experimentation
@Sam Biller thanks. I coincidentally found that article last night. Great info. Seems some drugs like Rapamycin clearly work, but others have minimal evidence, or only alleviate symptoms of old age,…
- Karl.1
- 5 yrs ago
- 3
- Self-Experimentation
- Reported - view
Re: Rapamycin self-experimentation
@Sam Biller did Dr Green explain what each you meds are for?
- Karl.1
- 5 yrs ago
- 2
- Self-Experimentation
- Reported - view
Re: Supplement sources
@David Hanson thanks. I also like Thorne, Jarrow, and Doctors Best. I also use Pure Encapsulations.
- Karl.1
- 5 yrs ago
- Questions & Answers
- Reported - view
Re: A different point of view
@Staffan Olsson thanks for the response and information. I guess the key is what happens after you use senolytics? Do those cells get replaced? Do you need stem cell therapy to do that?…
- Karl.1
- 5 yrs ago
- Senolytics Discussion
- Reported - view
Re: Telomerase Activators
Would be nice a have a forum section for Telomeres
- Karl.1
- 5 yrs ago
- 1
- Self-Experimentation
- Reported - view
A different point of view

Interesting article that argues for telomere therapy and against senolytics. https://www.leafscience.org/are-senolytics-potentially-damaging-for-longevity/
- Karl.1
- 5 yrs ago
- 8replies
- 306
- Senolytics Discussion
Supplement sources

Sorry if this has already been asked. What companies do you use/trust for non prescription supplements?
- Karl.1
- 5 yrs ago
- 2replies
- 86
- Questions & Answers
Re: [FAQ] How to work with the medical system
@Mike Almerjanski what am I confused about?
- Karl.1
- 5 yrs ago
- General Discussion
- Reported - view
Re: [FAQ] How to work with the medical system
@Mike Almerjanski are you accusing me of being a paid agitator? I ask you to keep an open mind, and be a scientist, not a cult member.
- Karl.1
- 5 yrs ago
- General Discussion
- Reported - view
Re: [FAQ] How to work with the medical system
Dan; A very informative post, but as a physician, I am going to disagree with several of your points, and hopefully add to everyone’s understanding of how the health care system works or doesn’t…
- Karl.1
- 5 yrs ago
- 3
- General Discussion
- Reported - view
Re: Azithromycin (Zithromax) as senolytic; a note of caution
@Dan I respect your personal experiences, but in a group of people taking Metformin, Rapamycin, Dasatinib, and Navitoclax, I don’t think Zithromax will be their biggest risk.
- Karl.1
- 5 yrs ago
- Senolytics Discussion
- Reported - view
Re: Senolytics
Charles; you listed 2 different senolytic regimens. How did you separate them?
- Karl.1
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Devil's Advocate
@David Hanson that there primary business is selling supplements is what should make you suspicious of what they put out. I would verify elsewhere any info you get from Life Extension.…
- Karl.1
- 5 yrs ago
- General Discussion
- Reported - view
Re: Devil's Advocate
@David Hanson I agree that Age-Reversal is not a big company, but they are some kind of business entity, and they ask for donations. The web site doesn’t give much of the usual “about us” info.…
- Karl.1
- 5 yrs ago
- General Discussion
- Reported - view
Devil's Advocate

I have spent a few days reading through this forum and this website, and most of what I see are educated posts from intelligent well meaning people. But, this is a field that is susceptible to scams,…
- Karl.1
- 5 yrs ago
- 5replies
- 116
- 1
- General Discussion
Re: Berberine
I also understand that Berberine and Metformin have similar actions and should not be taken together?
- Karl.1
- 5 yrs ago
- AMPK Activation
- Reported - view
Re: Introduction to senolytics
@David Hanson I don’t think there’s anything wrong with taking it daily. I also do. But it seems from what I’m reading, that senolytics probably should be taken in larger bolus amounts? I.e.…
- Karl.1
- 5 yrs ago
- 2
- Senolytics Discussion
- Reported - view
Re: Introduction to senolytics
No matter what senolytic you are taking, it sounds like you should take it in large intermittent doses? I.e. Quercetin is not a once a day supplement like most people probably take it.
- Karl.1
- 5 yrs ago
- 1
- Senolytics Discussion
- Reported - view
Berberine

Anyone taking Berberine supplement as an AMPK activator? Seems to have some literature documenting its use. https://diabetes.diabetesjournals.org/content/55/8/2256.full
- Karl.1
- 5 yrs ago
- 12replies
- 862
- AMPK Activation
Re: NUCHIDO
Does anyone else get a “Theranos” vibe watching her talk?
- Karl.1
- 5 yrs ago
- 1
- NAD+ Restoration
- Reported - view

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