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Re: Fisetin to Clear Senescent Cells
@Robert Olin I don’t mean to rain on your parade. I’m glad you’re here and getting involved in senolytics. There is great potential to slow or reverse aging.…
Karl
Karl.1
4 yrs ago
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@Robert Olin you are making the assumption that more is better?
Karl
Karl.1
4 yrs ago
Self-Experimentation
Reported - view
Re: Vitamin C and the Corona Virus
@John Tillson could not find any completed scientific randomized blinded study showing vitamin c treats Covid. Hopefully that will change.
Karl
Karl.1
4 yrs ago
Questions & Answers
Reported - view
Re: Vitamin C and the Corona Virus
@John Tillson you’d have to point out that evidence because I haven’t seen anything significant.
Karl
Karl.1
4 yrs ago
Questions & Answers
Reported - view
Re: Vitamin C and the Corona Virus
Unfortunately the results of studies of vitamin C in sepsis have not shown much success. https://pulmccm.org/critical-care-review/vitamin-c-didnt-improve-septic-shock-in-vitamins-trial/
Karl
Karl.1
4 yrs ago
Questions & Answers
Reported - view
Re: Senolytics
@Edward Meininger I have only taken D&Q once, but it kicked my ass. Nausea started at 2 hrs and last for about 10 hrs with vomiting at the end. Body aches and fatigue for several hrs,…
Karl
Karl.1
4 yrs ago
3
Self-Experimentation
Reported - view
Re: Sources of dasatinib
@Pablo Reinaldos López Dasatinib has a half life of 3-5 hrs.
Karl
Karl.1
4 yrs ago
Senolytics Discussion
Reported - view
Re: Preparations for self-treating COVID-19
@Florin now we need a double blind prospective study. Would be nice if one arm of the study did not include Azithromycin.
Karl
Karl.1
4 yrs ago
Self-Experimentation
Reported - view
Re: Senolytics
@Dan Nave great find. Unfortunately sounds like this would become a patented drug and fetch a high price?
Karl
Karl.1
4 yrs ago
1
Self-Experimentation
Reported - view
Re: rapamycin, trametinib, lithium combo
Nice find Jeff Anyone know how they came up with Trametinib?
Karl
Karl.1
4 yrs ago
Assessing Biological Age
Reported - view
Re: Azithromycin (Zithromax) as senolytic; a note of caution
@uzoma iwuagwu interesting data. Do you have a link?
Karl
Karl.1
4 yrs ago
Senolytics Discussion
Reported - view
Re: Preparations for self-treating COVID-19
3 studies this week in France, China, and Brazil show no benefit from Hydroxychloroquine in treating Covid. Hopefully more studies to come.
Karl
Karl.1
4 yrs ago
1
Self-Experimentation
Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes)
My wife and I have done two fisetin runs with no noticeable effects. D&Q next.
Karl
Karl.1
4 yrs ago
Senolytics Discussion
Reported - view
Re: Preparations for self-treating COVID-19
One more public service announcement. If you decide to get these medicines to take or have around in case, be aware that chloroquine falls in the category that toxicologists refer to as “one pill…
Karl
Karl.1
4 yrs ago
Self-Experimentation
Reported - view
Re: Preparations for self-treating COVID-19
@Florin don’t really care to argue with you if your source of medical information is local abc new. I would ask you to look at that story to see if it really passes any scientific review.
Karl
Karl.1
4 yrs ago
Self-Experimentation
Reported - view
Re: Events
Thanks for the info.
Karl
Karl.1
4 yrs ago
General Discussion
Reported - view
Re: Preparations for self-treating COVID-19
A lot of interesting discussion. Unfortunately its like talking with anti-vaxxers. People have made up their minds and not changing. My only purpose in posting here was to warn people that they may…
Karl
Karl.1
4 yrs ago
Self-Experimentation
Reported - view
Re: Berberine
@Joe smith Interesting article. I don't need the lipid lowering effect. My concern is why take a diabetic medicine if Berberine has the AMPK effect that is desired?
Karl
Karl.1
4 yrs ago
AMPK Activation
Reported - view
Re: Preparations for self-treating COVID-19
@Paul Beauchemin when you use the phrase “with all due respect “, it usually means you don’t respect. Thanks for the disrespect and stereotyping me. I hope nobody does the same to you.…
Karl
Karl.1
4 yrs ago
Self-Experimentation
Reported - view
Re: Preparations for self-treating COVID-19
@Paul Beauchemin thanks for letting me know what’s wrong with all doctors.
Karl
Karl.1
4 yrs ago
Self-Experimentation
Reported - view
Re: Preparations for self-treating COVID-19
An interesting article: Interaction of Metformin and Hydroxychloroquine https://www.biorxiv.org/content/10.1101/2020.03.31.018556v1
Karl
Karl.1
4 yrs ago
1
Self-Experimentation
Reported - view
Re: Preparations for self-treating COVID-19
@Paul Beauchemin as a physician I understand every drug has side effects. And I’m glad your wife has done well on Plaquenil. But Plaqnenil is a far more dangerous drug than Tylenol.
Karl
Karl.1
4 yrs ago
Self-Experimentation
Reported - view
Re: Preparations for self-treating COVID-19
@JGC I stand by my statement that a drug with dangerous side effects may or may not work.
Karl
Karl.1
4 yrs ago
Self-Experimentation
Reported - view
Re: Preparations for self-treating COVID-19
The original French study showed good results, although the study was small. A second French study claims good results but thorough review of it shows only questionable results.…
Karl
Karl.1
4 yrs ago
Self-Experimentation
Reported - view
Re: Preparations for self-treating COVID-19
@Steven Jacobs I don’t think the final word on Zithromax is in. Zithromax has properties beyond being an antibiotic and it may be its anti inflammatory property that helps.…
Karl
Karl.1
4 yrs ago
2
Self-Experimentation
Reported - view
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Karl
Karl.1
Arizona
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