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Re: SGLT2
@are we there yet was hoping for something a bit more scientific.
- Karl.1
- 3 yrs ago
- General Discussion
- Reported - view
Re: SGLT2
It looks to me like these herbal supplements have only been studied in vitro. And even if they do work, how do you determine a dose?
- Karl.1
- 3 yrs ago
- General Discussion
- Reported - view
Re: SGLT2
@Juan Daw great information. Thanks. Are you taking any of these?
- Karl.1
- 3 yrs ago
- General Discussion
- Reported - view
Re: SGLT2
@are we there yet what is website for Canadian pharmacy?
- Karl.1
- 3 yrs ago
- General Discussion
- Reported - view
Re: SGLT2
@Michael although both are meds for diabetes, I would not say it’s a replacement.
- Karl.1
- 3 yrs ago
- 1
- General Discussion
- Reported - view
Re: SGLT2
I just ordered some for the first time from “alldaychemist”. Will see how long it takes to get here.
- Karl.1
- 3 yrs ago
- General Discussion
- Reported - view
IndiaMart - how does it work?

Does anyone use indiamart and if so, how does it work? Do sellers send you emails to order?
- Karl.1
- 3 yrs ago
- 57
- Questions & Answers
Re: Mods definitely need to reduce the increasing amount of link spam on the forum.
There is obviously little if any monitoring of this site. Half the posts in General Discussion are people selling crap.
- Karl.1
- 3 yrs ago
- 2
- General Discussion
- Reported - view
Re: Has anyone tried urolithin A?
@Robin safran I take them with a meal, but I don’t think it matters. I think it works for more energy, but I take so many supplements it’s hard to say.…
- Karl.1
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Combination of rapamycin, rifampicin and allantoin in fruit flies
I’m beginning to think that almost anything will extend the life of a fruit fly 10-15%. I’ve started ignoring studies with that result.
- Karl.1
- 3 yrs ago
- General Discussion
- Reported - view
Re: D+Q+F+P+L+G+GLA: A New Senolytic Cocktail
@JGC you may very well be right, and it would be hard to find any “standard” symptoms of senescent cell death. I do get gastro symptoms from one time doses of ginger and dasatinib.…
- Karl.1
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: D+Q+F+P+L+G+GLA: A New Senolytic Cocktail
Why do you attribute your symptoms to senescence rather than to side effects of the substances you took?
- Karl.1
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Gingernone A is a Better-than-D+Q Senolytic
@JGC one man’s trash is another man’s treasure or so they say.
- Karl.1
- 3 yrs ago
- Self-Experimentation
- Reported - view
Is interested in life extension a male thing?

Although I see several life extension experts/scientists who are female, the vast majority of people on these forums are male. Is that correct and if so why?
- Karl.1
- 3 yrs ago
- 2replies
- 64
- Questions & Answers
Re: Senolytics- How many different ones do you take and why
@Brian Valerie lol. My wife already thinks we take too many pills. Don’t think I could take them all together. The Ginger doesn’t agree with my stomach, and the dasatinib kicks my ass.
- Karl.1
- 3 yrs ago
- 1
- Senolytics Discussion
- Reported - view
Senolytics- How many different ones do you take and why

I am assuming that a given Senolytic may not cause senolysis in all cell types and therefore it is probably better to rotate through different senolytics.…
- Karl.1
- updated 3 yrs ago
- 4replies
- 269
- 1
- Senolytics Discussion
Re: Rapamycin vs Metformin
@Juan Daw how is Withaferin an analogue of Rapamycin?
- Karl.1
- 3 yrs ago
- AMPK Activation
- Reported - view
Re: Juvan’s Neel skin gel
I believe active ingredient is GHK, which is not new to skin care. website is neel.bio
- Karl.1
- 3 yrs ago
- Questions & Answers
- Reported - view
Re: GlyNAC
I would say the big question is “does anything really extend life in humans?” Since studies are not done in humans, and it seems almost anything that stresses a worm or fly extends its life by 10%.…
- Karl.1
- 3 yrs ago
- Self-Experimentation
- Reported - view
Juvan’s Neel skin gel

Anybody trying this?
- Karl.1
- updated 3 yrs ago
- 9replies
- 291
- Questions & Answers
Re: Has anyone tried urolithin A?
@Roman Schepis yes, I saw that. I start taking Mitopure today. Have you noticed anything while taking it?
- Karl.1
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Has anyone tried urolithin A?
Does anyone think that since Urolithin A promotes Mitophogy, should it be taken like a senolytic instead of daily?
- Karl.1
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: PCC1 is senolytic and senomorphic
Does anyone have a dose for this as a senolytic? Thanks
- Karl.1
- 3 yrs ago
- Senolytics Discussion
- Reported - view
Re: Solved aging already but looking for new ideas...
Are you here to sell something?
- Karl.1
- 3 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: A hypothesis about Senescent Cells
Why would stem cells fail so often?
- Karl.1
- 3 yrs ago
- Senolytics Discussion
- Reported - view

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