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Rapamycin in humans
I'm cautious on pharmaceuticals but am considering Rapamycin. Downsides are cost, difficulty to source and potential side effects (some people suffer from stomach issues IIRC).…
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Paul's self experimentation
I inadvertently started on this 5 years ago when I started taking Metformin. Was diagnosed with a Gleason 6 prostate cancer. Docs didn't want to treat just monitor.…
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Menin, D-serine, and Neurological Age Reversal
There is a new report published in PLOS Biology by a Chinese group led by Lige Leng that provides evidence of a correlation between decline in the protein Menin secreted by the hypothalamus and a…
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NAD Test #3: Impact of 1000 mg NMN/d?
https://www.youtube.com/watch?v=9add0yV9zjs
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Quantifying NAD: Test #1 in 2023
https://www.youtube.com/watch?v=-hfdUXsCeN8
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Resting Heart Rate, Heart Rate Variability: Is Q1 2023 Better Than 2022?
https://www.youtube.com/watch?v=rttBUK4FxdM
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Fisetin - misc
1. Buying: I noticed this morning that a few products of Fisetin are either out-of-stock, or the price has increased considerably. I'm esp interested in 500 mg caps, but I saw one offering 1,000 mg.…
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Serine + Vitamin B6: The Best Way To Reduce Homocysteine? (Also, Homocysteine Activates mTORC1)
https://www.youtube.com/watch?v=MwtsA391OZ0
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Blood Test #2 in 2023: Diet Composition
https://www.youtube.com/watch?v=CdEEaf72rjE&t=1s
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Blood Test #2 in 2023: Impact of NMN?
https://www.youtube.com/watch?v=sSnK2YzlOfk
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Reduced Blood Pressure: Was It Caused By Lung Muscle Training?
https://www.youtube.com/watch?v=ynylZ9ZeIpg&t=1s
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Lung Muscle Training: Did It Improve Or Worsen Lung Function?
https://www.youtube.com/watch?v=a4Il4xMTkP4
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Blood Test #1 in 2023: Diet Composition
https://www.youtube.com/watch?v=L5a8gIB39uc
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Niacin (Vit B3) - Lowered my Cholesterol - 7 months experiment
Hi guys My first post here, I'm really enjoying reading all of these experiments. I know this forum is about age reversal, but having a high cholesterol level is also not good at all.…
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Epigenetic Test #4: What's My Biological Age?
https://www.youtube.com/watch?v=-MWbuFlFlOA
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Quantifying Biological Age: Blood Test #7 in 2022
https://www.youtube.com/watch?v=R7bxNDhKDLM
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Low-Dose Oral Minoxidil for Hair Regrowth
There is an interesting article in today's New York Times describing an accidental discovery by an Australian MD. He found that Minoxidil (trade name Rogaine) when taken orally at very low dose…
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The DIM Supplement and Wound Healing
Forgive me for introducing a topic to this Forum that is slightly off the topic on anti-aging. The supplement DIM (3, 3,-diindolylmethane) sold by Swanson ($8.…
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Low-Dose Oral Minoxidil for Hair Regrowth
There's an interesting article in today's New York Times. It describes the accidental discovery that taking a low dose of Minoxidil (i.e., Rogaine) orally instead of rubbing a high dose on your…
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Fisetin to Clear Senescent Cells
Following studies with mice that showed significant senolytic clearance of senescent cells following large doses of the readily available flavenoid supplement Fisetin,…
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Epigenetic Test #3: What's My Biological Age?
https://www.youtube.com/watch?v=BwJmuQ7ubkM
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Albumin: What's Optimal For Youth And Health? (2022 Update)
https://www.youtube.com/watch?v=Q3PXBl82uTk
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DHEA-S Is A Weakness In My Data: Blood Test #5 in 2022
https://www.youtube.com/watch?v=DHGyBOzcsfk
Share your story of trying or designing a promising age-reversal protocol.