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Self-Experimentation
Share your story of trying or designing a promising age-reversal protocol.
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About this forum topic
Hello everyone, Many of us are self-experimenting in an effort to prolong our good health. In this sub-forum, we encourage you to share your own stories of what seems to be working for you.…
Maximus Peto
Researcher, website & forum admin
Maximus
6 yrs ago
1229
15
Self-Experimentation
Fisetin to Clear Senescent Cells
Following studies with mice that showed significant senolytic clearance of senescent cells following large doses of the readily available flavenoid supplement Fisetin,…
JGC
Retired Professor of Physics
JGC
updated
3 yrs ago
766
replies
19041
20
Last reply
Dan Nave
1 yr ago
Self-Experimentation
Rapamycin Cost
Let me clear some things up for people considering rapamycin (generic sirolimus). I am taking it and so are my dogs!! (I have a very open-minded vet who trusts my judgement.) Dr.…
Rob8311
Rob8311
6 yrs ago
599
replies
14015
14
Last reply
Steve Roedde
1 yr ago
Self-Experimentation
Senolytics
I've just finished my third Senolytic cycle. Fisetin 1500 mgs on 2 consecutihve days repeated one month later Dasatinab 180 mgs on 2 consecutive days + Quercitn 2250 mgs on the same days I also take…
Charles Grashow
Charles_Grashow
4 yrs ago
128
replies
4212
8
Last reply
Wil
2 yrs ago
Self-Experimentation
Rapamycin - progress so far
Hi all, About me: I'm 46 y.o. medical doctor based in Europe and started taking weekly rapamycin 4 months ago. I go to the gym regularly and am in average physical condition for a guy of my age.…
Diamond Tree
Diamond_Tree
updated
2 yrs ago
86
replies
3158
7
Last reply
Jonas Huberman
9 mths ago
Self-Experimentation
Canagliflozin - A One Month Report, Its Good
I've been using Canagliflozin for the past month and really like it. It moderates blood glucose levels and makes it really easy to lose weight. I've lost about 10 lbs in 3 weeks,…
Brin Chikovski
Brin_Chikovski
updated
2 yrs ago
18
replies
817
6
Last reply
Alex K. Chen
1 yr ago
Self-Experimentation
"Senolytic Activator" and Extended Fasting …
Gentlefolk, Our fine friends at Life Extension have released a new product, Senolytic Activator. It is a combination of Quercertin and Theaflavins. They intend us to use it weekly as a…
adonoho
adonoho
5 yrs ago
36
replies
1931
6
Last reply
Marc Bauchet
2 yrs ago
Self-Experimentation
Anti-Aging Self-Experiment with Epitalon (AEDG)
There is a body of evidence, coming primarily from the publications of Vladimir Kh. Khavinson and his group at the Institute of Bioregulation and Gerontology (IB&G) in Moscow,…
JGC
Retired Professor of Physics
JGC
3 yrs ago
25
replies
1188
6
Last reply
Burgundy Summer
2 yrs ago
Self-Experimentation
Just Ordered Rapamycin w/ No Prescription
When I was at Raadfest18, it was announced that there was a vendor in the Exhibition Hall from whom Rapamycin could be ordered at a good price. Later I found out exactly what vendor from someone…
Mermaid
Mermaid
5 yrs ago
80
replies
6796
5
Last reply
Steve Roedde
1 yr ago
Self-Experimentation
Apigenin: An Alternative Way of Boosting NAD+
At the recent Ending Age-Related Diseases 2021 online conference, Dr. Eric Verdin of the Buck Institute gave a talk in which he described the mechanism behind the well-known drop in NAD+ with age,…
JGC
Retired Professor of Physics
JGC
2 yrs ago
22
replies
646
5
Last reply
Staffan Olsson
2 yrs ago
Self-Experimentation
Replacing Hormones to Optimal Levels
I’ve been experimenting with exogenous testosterone for over 15 years. At almost 73 I have been able to build and keep muscle. I eat a diet high in protein, lower in carbs and healthy fats.…
Sharon Smith
Sharon_Smith
2 yrs ago
27
replies
576
5
Last reply
Arizona Kid
2 yrs ago
Self-Experimentation
Rapamycin self-experimentation
I've just begun a 10 week self-experimentation with RapaPro rapamycin. I'll be taking 5 mg once a week, which is roughly the dose that Dr. Alan Green recommends on the high side and seems to be…
Tam
Tam
4 yrs ago
74
replies
3608
5
Last reply
Ludovic Debels
3 yrs ago
Self-Experimentation
The purity of Lucidias-brand Dasatinib
Last year I obtained a 60-tablet bottle of 50 mg Lucidias-brand Dasatinib from BonHoa Pharmacy in New Deli, India, link https://www.bonhoa.com. It seems to be manufactured by Lucius Pharmaceuticals…
JGC
Retired Professor of Physics
JGC
5 yrs ago
12
replies
470
5
Last reply
Louise B Andrew
4 yrs ago
Self-Experimentation
D+Q+F+P+L+G+GLA: A New Senolytic Cocktail
For my May 15-18 senolytic session I tried something new. In a recent Foresight Institute talk available on YouTube, James Kirkland identified the flavonoid Luteolin as a senolytic.…
JGC
Retired Professor of Physics
JGC
updated
1 yr ago
33
replies
709
4
Last reply
Michael_123
1 yr ago
Self-Experimentation
dasatinib (Dasa-Pro)
'NOTICE: By the end of July IAS will be offering dasatinib (Dasa-Pro) in 12x 40mg double-scored tablets for $99.99 this will be uploaded to www.antiaging.…
CSC
CSC
4 yrs ago
13
replies
522
4
Last reply
Erik A Aronesty
2 yrs ago
Self-Experimentation
Bio-Fisetin, a x25 Boost in Bioavailability?
One of the big problems with senolytic flavenoids like Fisetin and Quercetin is that they have a very low solubility in water and poor survival in the digestive tract,…
JGC
Retired Professor of Physics
JGC
3 yrs ago
13
replies
1062
4
Last reply
UB
2 yrs ago
Self-Experimentation
Finished the First 3 Protocol Steps
I an 72 and have been taking metformin (twice a day but recently increased to 3 times a day) for 5 years. I recently completed 6 patches of NAD+. I also have just taken 2 doses of quercetin and…
Bernie
Bernie_Singer
5 yrs ago
8
replies
427
4
Last reply
Ross Barker
3 yrs ago
Self-Experimentation
Paul's Anti-Aging Efforts
Preparing for a LONG FUTURE, here are the prescriptions and supplements I take to STOP or REVERSE AGING, with the blessings of my doctors. After each one are the number of Web sites mentioning them,…
Paul Mason
Paul_Mason
5 yrs ago
12
replies
1362
4
Last reply
Simon Lee
3 yrs ago
Self-Experimentation
Young plasma treatments in Tampa, Florida
My name is Howard Chipman MD and I have been treating patients with young plasma for anti-aging, dementia and other age related disorders for over a year with good results.…
Dr. Chipman
Dr_Chipman
6 yrs ago
3
replies
559
4
Last reply
Daniel Stephenson
4 yrs ago
Self-Experimentation
Photo evidence that the experiment is working
Correct me if I'm wrong. I figured that this deserves it's own discussion topic. More than 5 years ago I started doing age-reversal. Couple of years back when I realized that it was working I…
Andrew P K Yap
Andrew_P_K_Yap
2 yrs ago
109
replies
2312
3
Last reply
Andrew P K Yap
2 mths ago
Self-Experimentation
Preparations for self-treating COVID-19
The mortality rate of the aged population from COVID-19 is very high, around 20% for the over-80 group of which I and my wife are members. Further, if medical facilities are limited and physicians…
JGC
Retired Professor of Physics
JGC
4 yrs ago
88
replies
1116
3
Last reply
Vic Emmay
3 mths ago
Self-Experimentation
GlyNAC
Has anyone tried Glycine/N-acetylcysteine? It appears to have amazing effects on age reversal. Glycine and N‐acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency,…
Qimin You
Qimin_You
3 yrs ago
103
replies
5246
3
Last reply
martino lorenzon
9 mths ago
Self-Experimentation
Paul's self experimentation
I inadvertently started on this 5 years ago when I started taking Metformin. Was diagnosed with a Gleason 6 prostate cancer. Docs didn't want to treat just monitor.…
Paul Beauchemin
Paul_Beauchemin
4 yrs ago
66
replies
1288
3
Last reply
Alex
1 yr ago
Self-Experimentation
Menin, D-serine, and Neurological Age Reversal
There is a new report published in PLOS Biology by a Chinese group led by Lige Leng that provides evidence of a correlation between decline in the protein Menin secreted by the hypothalamus and a…
JGC
Retired Professor of Physics
JGC
1 yr ago
3
replies
134
3
Last reply
DrOhw
1 yr ago
Self-Experimentation
Low-Dose Oral Minoxidil for Hair Regrowth
There is an interesting article in today's New York Times describing an accidental discovery by an Australian MD. He found that Minoxidil (trade name Rogaine) when taken orally at very low dose…
JGC
Retired Professor of Physics
JGC
1 yr ago
9
replies
318
3
Last reply
Alerk Kross
1 yr ago
Self-Experimentation
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