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Self-Experimentation
Share your story of trying or designing a promising age-reversal protocol.
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Rapamycin in humans
I'm cautious on pharmaceuticals but am considering Rapamycin. Downsides are cost, difficulty to source and potential side effects (some people suffer from stomach issues IIRC).…
Dan
moderator
skipping my funeral
dantheman
5 yrs ago
41
replies
948
1
Last reply
Alex
1 yr ago
Self-Experimentation
Rilmenidine 19% life extension calorie memic not sold in us
are we there yet
are_we_there_yet
1 yr ago
56
1
Self-Experimentation
Quantifying NAD: Test #1 in 2023
https://www.youtube.com/watch?v=-hfdUXsCeN8
michael lustgarten
michael_lustgarten
1 yr ago
1
reply
28
1
Last reply
michael lustgarten
1 yr ago
Self-Experimentation
Blood Test #1 in 2023: Diet Composition
https://www.youtube.com/watch?v=L5a8gIB39uc
michael lustgarten
michael_lustgarten
1 yr ago
1
reply
41
1
Last reply
Lena Twian
1 yr ago
Self-Experimentation
Epigenetic Test #4: What's My Biological Age?
https://www.youtube.com/watch?v=-MWbuFlFlOA
michael lustgarten
michael_lustgarten
1 yr ago
32
1
Self-Experimentation
Low-Dose Oral Minoxidil for Hair Regrowth
There's an interesting article in today's New York Times. It describes the accidental discovery that taking a low dose of Minoxidil (i.e., Rogaine) orally instead of rubbing a high dose on your…
JGC
Retired Professor of Physics
JGC
updated
1 yr ago
5
replies
217
1
Last reply
Michael
1 yr ago
Self-Experimentation
Epigenetic Test #3: What's My Biological Age?
https://www.youtube.com/watch?v=BwJmuQ7ubkM
michael lustgarten
michael_lustgarten
1 yr ago
29
1
Self-Experimentation
Suggestion / challenge
Many on this site are taking F + Q , hit-and-run protocol, generally with positive results -- and perhaps just as important, few negative side effects.…
Michael_123
A is A
Michael_123
1 yr ago
47
1
Self-Experimentation
Resting Heart Rate And Heart Rate Variability: What's Optimal, 1,502 Days of Data
https://www.youtube.com/watch?v=8fIIJTQ4xzo
michael lustgarten
michael_lustgarten
1 yr ago
26
1
Self-Experimentation
My 80 year old father's proposed regimen. What do you think?
Hi, I'd appreciate a few moments of your time. This is for my 80 year old father. He takes no prescription meds but is in rough shape due to his age and years of less than ideal lifestyle (which we…
cjacek
cjacek
1 yr ago
17
replies
264
1
Last reply
Spasov
1 yr ago
Self-Experimentation
Deprenyl (Selegiline) as a Longevity Drug?
Prompted by UW Professor Matt Kaeberlein's participation in a panel discussion on ARDD 2022 this morning, I listened to the audio of Kaeberlein's long podcast interview with Tim Ferriss.…
JGC
Retired Professor of Physics
JGC
1 yr ago
3
replies
158
1
Last reply
Staffan Olsson
1 yr ago
Self-Experimentation
Rapamycin cost
Well-studied results show a huge increase in lifespan across the board among mammals with rapamycin (sirolimus CAS 53123-88-9) dosing. Why is not everyone taking it?…
Bart Bear
Bart_Bear
2 yrs ago
3
replies
279
1
Last reply
Laur
1 yr ago
Self-Experimentation
Yeast-Displayed GDF11 and Oral Delivery
Through the work of Steve Perry, it appears that taking growth differentiation factor 11 (GDF11) provides definite health benefits and some evidence of rejuvenation.…
JGC
Retired Professor of Physics
JGC
1 yr ago
4
replies
127
1
Last reply
Jay Orman
1 yr ago
Self-Experimentation
Blood Test #1 in 2022: Supplements, Fitness, Diet
https://www.youtube.com/watch?v=46_Xkj9xQug
michael lustgarten
michael_lustgarten
2 yrs ago
3
replies
94
1
Last reply
shirleyscaringi
1 yr ago
Self-Experimentation
Cosmetic Peptides
Anyone have experience with any of the (cosmetic) peptides on this site or equivalent? Tried the rapa cream formula suggested on the forum here with zero benefit.…
Michael
Michael.1
3 yrs ago
3
replies
208
1
Last reply
Rick Tolk
1 yr ago
Self-Experimentation
Dasatinib update
Just finished a 3 day course of D & Q. The Dasatinib was purchased from Taylor Made Compounding. Dosage was 100 mg D &1000 mg Q. Cost for 6 @50 mg capsules, including shipping was USD $33.…
Charles Grashow
Charles_Grashow
3 yrs ago
21
replies
726
1
Last reply
Jared
1 yr ago
Self-Experimentation
Testosterone Trials
The Testosterone Trials were a set of seven randomized placebo-controlled trials that evaluated the efficacy of testosterone replacement therapy (TRT) in older men with low testosterone levels,…
Michael
Michael.1
2 yrs ago
6
replies
248
1
Last reply
Michael
1 yr ago
Self-Experimentation
Recent constellation has had an effect... again
I wish I had more scientific data to bring, but in messy real life we end up trying various things and it muddies the waters. I've got existing benefits from a heap of stuff already,…
Jack Black
Jack_Black
2 yrs ago
1
reply
130
1
Last reply
Jack Black
2 yrs ago
Self-Experimentation
Rapamycin & Covid
Recently the new Omicron BA2 variant busted through the triple vaxed fortress my family had built. I was ill for a few days, but never felt in danger. When the illness subsided I suffered from…
Jack Black
Jack_Black
2 yrs ago
1
reply
72
1
Last reply
Jay Orman
2 yrs ago
Self-Experimentation
Longevity Achieved
Recently received my results on my biological age. To my surprise, my biological age is 15. The process to get to this point was difficult. My formula has proven itself over and over.…
Richard Brook
Richard_Brook
2 yrs ago
38
replies
1008
1
Last reply
Spasov
2 yrs ago
Self-Experimentation
Berberine and Melatonin - can this reverse aging of cells?
I am using an unusual mix of Melatonin (taken in the middle of the night,early morning really) and Berberine. This video explains the reasons why this has the potential to demethylate the epigenome…
John Hemming
John_Hemming
2 yrs ago
9
replies
657
1
Last reply
John Hemming
2 yrs ago
Self-Experimentation
Regimens for Healthy Longevity? NMN etc...
Hello to all of you wanting to live a healthy longer life... I think it would be productive to see what everybody is taking and results if any? I'll make a list of mine and post it,…
John Ramos
John_Ramos
2 yrs ago
83
1
Self-Experimentation
List of Reliable Online Pharmacies for Buying Rapamycin, etc.
See here: https://www.rapamycin.news/t/list-of-reliable-online-pharmacies-for-buying-rapamycin-etc/437
Brin Chikovski
Brin_Chikovski
2 yrs ago
61
1
Self-Experimentation
Feeling pretty sick after taking Fisetin. Thoughts?
So, I recently acquired a bottle of life extension's bio-fisetin. I took 10 pills a day for 3 days straight, seeking senotherapeutic effects. On the first day, everything was more or less fine.…
John
John.6
2 yrs ago
1
reply
335
1
Last reply
Dan Nave
2 yrs ago
Self-Experimentation
Rapamycin and muscle mass
I often hear rapamycin touted as a way of preserving muscle mass but mTOR is vital for muscle hypertrophy? Can anyone explain this apparent contradiction?…
DAVID W
DAVID_WOODHOUSE
2 yrs ago
4
replies
240
1
Last reply
Michael
2 yrs ago
Self-Experimentation
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Self-Experimentation
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Human Age Reversal Discussions
AMPK Activation
GDF11 Restoration
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Senolytics Discussion
Thymus Regeneration
Young Plasma Infusions
Questions & Answers
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