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Self-Experimentation
Share your story of trying or designing a promising age-reversal protocol.
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The DIM Supplement and Wound Healing
Forgive me for introducing a topic to this Forum that is slightly off the topic on anti-aging. The supplement DIM (3, 3,-diindolylmethane) sold by Swanson ($8.…
JGC
Retired Professor of Physics
JGC
updated
1 yr ago
6
replies
189
3
Last reply
chuck stanley
1 yr ago
Self-Experimentation
D.I.Y. patches for supplement delivery
Is anyone else interested in making your own patches for supplement delivery? Patches are not strictly about age-reversal. They can be used for other vitamins & supplements, too.…
Mike Almerjanski
Mike_Almerjanski
updated
4 yrs ago
9
replies
461
3
Last reply
Michael_123
1 yr ago
Self-Experimentation
Gingernone A is a Better-than-D+Q Senolytic
A post in Lifespan.io discusses a recent paper published last month in PLoS One in which the polyphenol Gingernone A, a strong component of Ginger Root Extract,…
JGC
Retired Professor of Physics
JGC
2 yrs ago
8
replies
373
3
Last reply
Karl
1 yr ago
Self-Experimentation
wrinkle reduction
has anyone noticed wrinkle reduction in systemic use of sirolimus?
curious
curious
3 yrs ago
107
replies
2092
3
Last reply
Hello World
2 yrs ago
Self-Experimentation
HBOT and Rapamycin protocol
Greetings! I just signed up to this forum. I've been looking for something like this so I could bounce ideas off the group. I recently bought a Hyperbaric Chamber and have been using it off and on.…
Bart Balder
Bart_Balder
2 yrs ago
15
replies
312
3
Last reply
Burgundy Summer
2 yrs ago
Self-Experimentation
Using chelation for cardiovascular health
I wasn't sure if this was an appropriate topic for a longevity discussion. But, with further thought, I figured any process that helps extend my life is appropriate.…
Jay Galambos
Jay_Galambos
5 yrs ago
6
replies
166
3
Last reply
James
2 yrs ago
Self-Experimentation
How to increase the bioavailability of Fisetin
I'm preparing to do a Fisetin senolytic experiment, but I've read on the article from Mayo Clinic ( https://linkinghub.elsevier.com/retrieve/pii/S2352396418303736 ) that the administration mode was…
JPA
JPA
5 yrs ago
110
replies
6439
3
Last reply
Robert Uomini
2 yrs ago
Self-Experimentation
Gamma-Linolenic Acid (GLA), Blood Autophagy, and Phenotypic Age
A recent study published in Nature indicates that as mice age, the autophagy mechanism that clears old and damaged red blood cells falters, reducing the effectiveness of their blood circulation.…
JGC
Retired Professor of Physics
JGC
3 yrs ago
22
replies
359
3
Last reply
aribadabar
2 yrs ago
Self-Experimentation
7 months taking rapamune
I have lived in Mexico for 9 years. After catching an article about rapamycin I found that I could get it here, without a prescription. Farmalisto in Mexico City to be exact but they do not ship to…
Dale Duke
Dale_Duke
4 yrs ago
1
reply
241
3
Last reply
uzoma iwuagwu
4 yrs ago
Self-Experimentation
Reversing arteriosclerotic disease
I think the forum could benefit from the topic “reversing arteriosclerotic disease”. This since arteriosclerosis is one of the main culprits that shorten the life of many human beings.…
Staffan Olsson
Staffan_Olsson
4 yrs ago
11
replies
361
3
Last reply
Staffan Olsson
4 yrs ago
Self-Experimentation
enhancing NAD precursor effectiveness
Therapeutic doses of NR and NMN in studies are usually much larger than the suggested amount on the label. Chromadex NR studies usually use a gram or more of the stuff,…
Ajax
Ajax
4 yrs ago
6
replies
381
3
Last reply
Dorian Gray
4 yrs ago
Self-Experimentation
Rapamycin Side Effect
Just read a recent addition to Dr. Green's site. I'll just post part of what he says. I don't get the impression he thinks it is a reason to stop treating, but important to be aware of.…
Rob8311
Rob8311
5 yrs ago
67
replies
1365
3
Last reply
Vincent Stona
4 yrs ago
Self-Experimentation
Share, Please
I've seen a post or two of someone talking about taking dasatinib + quercitin. I've even seen a detailed dosage schedule and mention of a list of compounding pharmacies that I can't find.…
Rob8311
Rob8311
5 yrs ago
5
replies
274
3
Last reply
Peter5.0
5 yrs ago
Self-Experimentation
Dr Peter Attia on Rapamycin
Peter Attia is somebody I follow after seeing him in discussions with Dr Rhonda Patrick, both of whom are researchers in longevity. He switched from surgery to longevity and has practices in NYC and…
Dan
moderator
skipping my funeral
dantheman
updated
5 yrs ago
8
replies
856
3
Last reply
are we there yet
5 yrs ago
Self-Experimentation
Is spontaneous hair colour restoration normal?
So, I am a 44yo male with a speckling of grey hair, and I have been taking a mix of compounds that are often discussed in the forums. I started in about mid-January this year.…
David Ng
David_Ng
updated
2 yrs ago
17
replies
1350
2
Last reply
Allen DeLaney
2 mths ago
Self-Experimentation
First post!.... Introducing myself!
Hi everyone!!! Just call me Lucky So, I'm currently 61 years old and I've been a lifetime exercise and diet enthusiast. In my late teens and early 20's I was a competitive powerlifter and…
Donkey Hotie
Donkey_Hotie
11 mths ago
4
replies
94
2
Last reply
Moonlitnight
4 mths ago
Self-Experimentation
Possible negative response to oral NAD+
Hello, My wife and I (~50) have started a NAD+ regime in addition to rest of the other life long regime (vegan, exercise, other suppls). We started with 250mg (sourced from Life Extension),…
Dan
moderator
skipping my funeral
dantheman
5 yrs ago
18
replies
1125
2
Last reply
Jay Orman
10 mths ago
Self-Experimentation
Serine + Vitamin B6: The Best Way To Reduce Homocysteine? (Also, Homocysteine Activates mTORC1)
https://www.youtube.com/watch?v=MwtsA391OZ0
michael lustgarten
michael_lustgarten
1 yr ago
30
2
Self-Experimentation
Niacin (Vit B3) - Lowered my Cholesterol - 7 months experiment
Hi guys My first post here, I'm really enjoying reading all of these experiments. I know this forum is about age reversal, but having a high cholesterol level is also not good at all.…
Lena Twian
Lena_Twian
1 yr ago
89
2
Self-Experimentation
An alternative criterion for evaluating a senolytic.
I apologize in advance for my bad English! Quantifying the effectiveness of senolytics is a task for which methodologies are still being developed. Throughout the years,…
Spasov
Spasov
2 yrs ago
8
replies
223
2
Last reply
Michael_123
1 yr ago
Self-Experimentation
Current longevity protocol: Should I add rapamycin?
This is my first post here, and I’m hoping to get some insights from people with similar protocols. In particular, I’m curious to hear people’s perspective on rapamycin given my current regimen.…
Simon Smith
Simon_Smith
2 yrs ago
26
replies
552
2
Last reply
Peter H. Howe
1 yr ago
Self-Experimentation
Protocol which makes senescent cells start to function and hair to grow
https://johnhemming.blogspot.com/2022/06/protocol-which-makes-senescent-cells.html I have put a link to my blog post about my new protocol which is designed to get senescent cells to exit senescence…
John Hemming
John_Hemming
1 yr ago
2
replies
208
2
Last reply
John Hemming
1 yr ago
Self-Experimentation
Where to buy rapamycin?
Hey everyone, I’m new to the group. Really cool to see everyone’s experience with Rapamycin. I’m looking to get some myself. I’m actually more interested in it for my cat’s heart condition.…
Stefan Pougatchev
Stefan_Pougatchev
2 yrs ago
21
replies
1110
2
Last reply
Karina
1 yr ago
Self-Experimentation
Has anyone tried urolithin A?
Urolithin A is a bacterial metabolite that enhances mitophagy, which declines as we age and allows dysfunctional mitochondria to accumulate. I just wanted to see if anyone has experimented with…
Will Hunter
Will_Hunter
3 yrs ago
31
replies
1526
2
Last reply
Karl
1 yr ago
Self-Experimentation
Dasatinib
Hi Brian, On the website "SocietyforAgeReversal.org which is the same as rescueelders.org I think. You mentioned in the blog, "I'm taking a very quick break from the engaging presentations to report…
Snowbird
Snowbird
5 yrs ago
113
replies
2562
2
Last reply
Rob8311
2 yrs ago
Self-Experimentation
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