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Re: Photo evidence that the experiment is working I was also born in 1960. I have a different approach to this which is driven by tests although I accept how people look in terms of hair/skin is a factor.…
- John Hemming
- John_Hemming
- 6 days ago
- Self-Experimentation
- Reported - view
Re: Anyone actually experience marked increased energy from NMN? @Michael yes
- John Hemming
- John_Hemming
- 11 days ago
- 1
- Self-Experimentation
- Reported - view
Re: Warning for those considering Rapamycin.news @Michael_666 I am with @Paul Beauchemin on this. There are more likely to be detailed evidence based discussions on that forum than generally other forums.…
- John Hemming
- John_Hemming
- 4 mths ago
- General Discussion
- Reported - view
Its the long genes that stop working
https://johnhemming.blogspot.com/2022/12/its-long-genes-that-stop-working.html People who read my blog will be aware that I have for some time argued that most (if not all) diseases of aging are…
- John Hemming
- John_Hemming
- 5 mths ago
- 32
- General Discussion
Further on getting cells to work properly
I have done an updated video.
- John Hemming
- John_Hemming
- 5 mths ago
- 46
- Self-Experimentation
Re: Photo evidence that the experiment is working @Michael I posted the following elsewhere and repeat it here: I do weekly blood tests. I use a few labs for complex historical reasons and I wanted to run a test where a sample taken through the…
- John Hemming
- John_Hemming
- 6 mths ago
- Self-Experimentation
- Reported - view
Re: Photo evidence that the experiment is working @Andrew P K Yap We don't have to agree on everything. My own personal view is that the health/age of a body is driven by the load of cells which are not functioning properly.…
- John Hemming
- John_Hemming
- 6 mths ago
- 1
- Self-Experimentation
- Reported - view
Re: Photo evidence that the experiment is working @Andrew P K Yap The blood values, however, are worth tracking to identify things like whether kidney function is improving or deteriorating. That is in part the reasoning behind the Levine algorithm.…
- John Hemming
- John_Hemming
- 6 mths ago
- Self-Experimentation
- Reported - view
Re: Photo evidence that the experiment is working The general blood work does give some indications perhaps better than the epigenetic clocks.
- John Hemming
- John_Hemming
- 6 mths ago
- Self-Experimentation
- Reported - view
Re: Photo evidence that the experiment is working As a matter of curiosity what do your blood biomarkers say?
- John Hemming
- John_Hemming
- 6 mths ago
- Self-Experimentation
- Reported - view
Paper: Causal analysis identifies small HDL particles and physical activity as key determinants of longevity of older adults
https://www.thelancet.com/action/showPdf?pii=S2352-3964%2822%2900474-1 Summary Background The hard endpoint of death is one of the most significant outcomes in both clinical practice and research…
- John Hemming
- John_Hemming
- 8 mths ago
- 1 reply
- 24
- Assessing Biological Age
Human age reversal: Fact or fiction?
https://onlinelibrary.wiley.com/doi/full/10.1111/acel.13664 Abstract Although chronological age correlates with various age-related diseases and conditions,…
- John Hemming
- John_Hemming
- 10 mths ago
- 64
- General Discussion
Re: D+Q+F+P+L+G+GLA: A New Senolytic Cocktail @JGC IL-6 has a similar problem. CRP is a good compromise people need to be aware of its limitations.
- John Hemming
- John_Hemming
- 10 mths ago
- Self-Experimentation
- Reported - view
Re: D+Q+F+P+L+G+GLA: A New Senolytic Cocktail @Chris M My view is that it is in fact the IL-10 levels in groups of cells that drives this. IL-10 is part of SASP and is in theory anti-inflammatory. Because it drives down NF Kappa B,…
- John Hemming
- John_Hemming
- 10 mths ago
- 2
- Self-Experimentation
- Reported - view
Re: D+Q+F+P+L+G+GLA: A New Senolytic Cocktail @Chris M I think CRP is useful as it depends in part on IL-6 and is not particularly expensive to test for. There can be problems when CRP goes too low for the sensitivity of the test,…
- John Hemming
- John_Hemming
- 11 mths ago
- Self-Experimentation
- Reported - view
Re: Protocol which makes senescent cells start to function and hair to grow @Spasov В момента не оповестявам протокола публично. Ако хората се споразумеят за Споразумение за неразкриване (NDA) с мен, тогава ще го обсъдя. Не моля за плащане,…
- John Hemming
- John_Hemming
- 11 mths ago
- 1
- Self-Experimentation
- Reported - view
Protocol which makes senescent cells start to function and hair to grow
https://johnhemming.blogspot.com/2022/06/protocol-which-makes-senescent-cells.html I have put a link to my blog post about my new protocol which is designed to get senescent cells to exit senescence…
- John Hemming
- John_Hemming
- 11 mths ago
- 2 replies
- 187
- 2
- Self-Experimentation
Re: Gingernone A is a Better-than-D+Q Senolytic I buy ginger in quantity (sushi ginger) and eat a bit quite frequently. I am doing very well with my current cellular health protocol, but I don't think the main issue is the ginger.
- John Hemming
- John_Hemming
- 1 yr ago
- Self-Experimentation
- Reported - view
Re: Is spontaneous hair colour restoration normal? I have been trying out various things over the past couple of years and in fact I have had a very gradual colouring of part of my hair, but more recently it has accelerated.…
- John Hemming
- John_Hemming
- 1 yr ago
- 1
- Self-Experimentation
- Reported - view
Re: Gingernone A is a Better-than-D+Q Senolytic @JGC when this experiment ends in a few months or less i intend to share the results. At that point i may be able to persuade you of this thesis.
- John Hemming
- John_Hemming
- 1 yr ago
- 3
- Self-Experimentation
- Reported - view
Re: Gingernone A is a Better-than-D+Q Senolytic My current experiment drives me to the conclusion that it is possible to get stem cells that have gone senescent to properly differentiate and that is a much better solution that killing them off…
- John Hemming
- John_Hemming
- 1 yr ago
- Self-Experimentation
- Reported - view
Re: Berberine and Melatonin - can this reverse aging of cells? This paper is interesting https://openheart.bmj.com/content/9/1/e001801.long It implies that adding Ferulic Acid to the Berberine/Melatonin combination would be helpful.
- John Hemming
- John_Hemming
- 1 yr ago
- Self-Experimentation
- Reported - view
Re: Berberine and Melatonin - can this reverse aging of cells? I now think that plasma citrate levels help in ensuring that stem cells differentiate. Melatonin helps with this by preventing oxidative stress, but the key part is the plasma citrate levels (a way…
- John Hemming
- John_Hemming
- 1 yr ago
- Self-Experimentation
- Reported - view
Re: A Spreadsheet for Calculating Your Levine Phenotypic Age @Michael The difficulty is that isolating out the cause and effect of any particular change is difficult. People tell me I am less inflamed and the levine spreadsheet has a lower mortality,…
- John Hemming
- John_Hemming
- 1 yr ago
- 1
- Assessing Biological Age
- Reported - view
Re: A Spreadsheet for Calculating Your Levine Phenotypic Age @John Hemming I am now running this every 4 weeks and now get DNAm at 49.43. I am wondering if the Molecular Hydrogen has accelerated the process of reducing inflammation.
- John Hemming
- John_Hemming
- 1 yr ago
- Assessing Biological Age
- Reported - view

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