wrinkle reduction

has anyone noticed wrinkle reduction in systemic use of sirolimus?

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    • garland
    • garland
    • 2 yrs ago
    • Reported - view

    Yes good point Ross.... The good thing about the cream is that it does get rid of  most senelytic cells according to the research study..... so it has profound anti aging effects as well as cosmetic purposes. For me it got rid of 80 % of my wrinkles under my eyes.... and more than 60& of my crepey skin under my arms....plus it gets rid of aged cells..... and it is cheap..

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      • Michael
      • Michael.1
      • 2 yrs ago
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      garland Is this still working for you? Have the results become more noticeable?

      Thank you

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      • garland
      • garland
      • 2 yrs ago
      • Reported - view

      Michael  yes but the most amazing thing is that the results seem to be mostly permutant. ... It is not perfect but everyone I have talked with who knew me before says i look 15 years younger and my skin is radically different. I have been to doctors who specialize is lasers etc...who have known me before I started this. I have been taking a break from the treatments for the past month.. I do put several other products on my face and eyes as well... Including Hyaluronic Acid. which seems to help make the results more permanent. Remember that makes this unique is that the treatments get rid of senolytic cells which other treatment modalities do not do...

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      • Michael
      • Michael.1
      • 2 yrs ago
      • Reported - view

      garland Good to hear. Thank you

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  • The comments above about skin elasticity caught my attention. I haven't used the sirolimus lotion yet. I have completed about 4 months of daily collagen peptides (in a morning coffee) plus daily hyaluronic acid pills and vitamin C in the form of 1 or 2 lemons. (Sometimes I'm just making chicken bone broth instead of the collagen peptide powder, but it's mostly the powder). Alas I've also found the more expensive hyaluronic acid pills (higher molecular weight) do indeed seem to make more difference and annoy my stomach less.

    Jury is still out on fine lines, I'm taking regular photos in controlled light and will report on that. What I can say though is that my skin elasticity has improved.

    I'm 50 and was starting to get some sag, and pinch test on the hand would take a few seconds to revert. Now the skin on my hand reverts instantly, so there is improvement. (Also I have less sag under the chin but that could be down to fixing my metabolism this year and no longer having high insulin, water retention and all that jazz; material for another post)

    I find this very heartening, as connective tissues are also supposed to benefit. Off topic I have noticed that just a week after starting collagen peptides my hip joint (post injury) stopped aching. Others online mention positive things about joint pain too. 

    My one concern about collagen peptides is whether this is triggering mTOR as a high protein diet would. On the bright side my particular supplement has low levels of Methionine, which might help there.

    Anyhow, I post the one year difference photo below and you be the judge. Skin sag under chin gone, lines around eyes maybe a little, not sure. But there is also 18kg weight loss between photos, it's been a busy year and difficult to tease out cause and effect.

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      • Michael
      • Michael.1
      • 2 yrs ago
      • Reported - view

      Jack Black Nice progress!

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  • Jack Black Looks like you've lost weight which also helps

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