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Re: Current longevity protocol: Should I add rapamycin?
@Ludovic Debels thanks! Have you seen any benefits? Biomarkers? Qualitative?
- Simon_Smith
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Current longevity protocol: Should I add rapamycin?
@SCOTT WEANER thanks. Appreciated!
- Simon_Smith
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Current longevity protocol: Should I add rapamycin?
@SCOTT WEANER appreciated. Last question (for now :)). Do you pulse the rapamycin, X weeks on and then X weeks off?
- Simon_Smith
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Current longevity protocol: Should I add rapamycin?
@SD thanks! Going to use my Promethease account to look up that gene.
- Simon_Smith
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Current longevity protocol: Should I add rapamycin?
@SD will do some research on ferritin. I wonder if there's any population data out there on mortality risk of different levels.
- Simon_Smith
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Current longevity protocol: Should I add rapamycin?
@SCOTT WEANER great to hear! Would you mind sharing your dose and dosing regimen for each drug? And how long have you been using them together? (Also, any other details of your regimen that you're…
- Simon_Smith
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Current longevity protocol: Should I add rapamycin?
@SD thanks for this. I was doing caloric restriction, then added metformin, and then added progressive resistance training, switching from a body weight-only workout.…
- Simon_Smith
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Current longevity protocol: Should I add rapamycin?
@SCOTT WEANER thanks! I listened to Attia's interview with Kaeberlein the other day. He didn't talk explicitly about combining metformin with rapamycin, though, from what I recall.
- Simon_Smith
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Current longevity protocol: Should I add rapamycin?
@Flavio Ferlitz thanks! I practiced caloric restriction for several years but found myself losing too much muscle mass. This actually accelerated when I began doing progressive resistance training…
- Simon_Smith
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Current longevity protocol: Should I add rapamycin?
Forgot to also include l-theanine, ashwagandha, and melatonin as other current interventions.
- Simon_Smith
- 3 yrs ago
- Self-Experimentation
- Reported - view
Current longevity protocol: Should I add rapamycin?

This is my first post here, and I’m hoping to get some insights from people with similar protocols. In particular, I’m curious to hear people’s perspective on rapamycin given my current regimen.…
- Simon_Smith
- 3 yrs ago
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- Self-Experimentation

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