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Self-Experimentation
Share your story of trying or designing a promising age-reversal protocol.
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Fisetin for Immune System
I started taking a low dose of Fisetin a little over a year ago. I take about 20 supplements. In the past year I have not been sick once and I have been around many sick people.…
JOHN
JOHN.1
updated
4 yrs ago
2
replies
315
Last reply
Carol Lee
2 yrs ago
Self-Experimentation
Rapamycin and APOE4 gene.
According to Dr. Alan Green, Rapamycin is particularly effective in APOE4 carriers, ameliorating the effects of atherosclerosis and Alzheimer's. Does anyone have any experience with either of these…
Jonathan Horwitz
Jonathan_Horwitz
4 yrs ago
12
replies
315
Last reply
MAC
4 yrs ago
Self-Experimentation
ALA/ALC
Hi folks, glad to find a group and forum of other folks interested in helping themselves and others defeat aging. I'm going to do a number of posts on the results of my personal research and…
Dan
moderator
skipping my funeral
dantheman
5 yrs ago
6
replies
315
1
Last reply
Dan Nave
4 yrs ago
Self-Experimentation
HBOT and Rapamycin protocol
Greetings! I just signed up to this forum. I've been looking for something like this so I could bounce ideas off the group. I recently bought a Hyperbaric Chamber and have been using it off and on.…
Bart Balder
Bart_Balder
2 yrs ago
15
replies
312
3
Last reply
Burgundy Summer
2 yrs ago
Self-Experimentation
Kaufmann Protocol Analysis
Dr. Sandra Kaufman, an MD anesthesiologist with an interest in aging, wrote a 2017 book entitled The Kaufmann Protocol: Why We Age and How to Stop It, in which she describes her approach to…
JGC
Retired Professor of Physics
JGC
4 yrs ago
9
replies
308
2
Last reply
Dan
moderator
4 yrs ago
Self-Experimentation
Calorie Restriction, Eat Once Every Other Day (EOD Diet)
I'm thinking about doing this. I'm not sure if I will have the will power to do so. The EOD Diet will reduce my calorie intake by more than 50%. My goal is to reduce my epigenetic age.…
Jimmy
Jim_N
updated
3 yrs ago
12
replies
304
Last reply
Michael
2 yrs ago
Self-Experimentation
Kidney Function Declines During Aging-Can It Be Reversed?
In the video: Data for changes in kidney function during aging, kidney function values that are associated with an increased risk of death for all causes What's my data for kidney function,…
michael lustgarten
michael_lustgarten
3 yrs ago
10
replies
304
Last reply
Edward Meininger
3 yrs ago
Self-Experimentation
Do doctors prescribe rapamycin to people in their 20s?
I'm looking to experiment with Rapamycin. Does anyone have experience with getting it in their 20s?
rapalogical
rapalogical
3 yrs ago
9
replies
303
Last reply
Arizona Kid
2 yrs ago
Self-Experimentation
Previous progress? Hope for the future!
I did say id share my progress of anti aging attempts. This is a 4 year gap between these pictures. In the first (I'm the one with the shades and tye die shirt) I had just turned 22 in the next…
Red_Alchemist
Ashley_Faul
5 yrs ago
298
1
Self-Experimentation
Paul's self experiment II
My original thread was hi-jacked so starting another Still taking rapamycin. Experimented with GDF11 and will take blood tests in Jan to see if it has had an effect Looking into peptides.…
Paul Beauchemin
Paul_Beauchemin
3 yrs ago
2
replies
294
1
Last reply
Jay Orman
9 mths ago
Self-Experimentation
Water only fasting
Bill Faloon (and others) are a fan of calorie restriction but as Aubrey De Grey has mentioned our best research and finally well established that long term restriction does not have the effect in…
Dan
moderator
skipping my funeral
dantheman
5 yrs ago
290
1
Self-Experimentation
Rapamycin
I have done bio identical hormones for 3 1/2 months before I start Rapamycin. Do I take 5 mg once a week for 3 months and then take a month off and start again?
Suzanne
Suzanne
4 yrs ago
5
replies
286
Last reply
Larry
4 yrs ago
Self-Experimentation
Rapamycin cost
Well-studied results show a huge increase in lifespan across the board among mammals with rapamycin (sirolimus CAS 53123-88-9) dosing. Why is not everyone taking it?…
Bart Bear
Bart_Bear
2 yrs ago
3
replies
279
1
Last reply
Laur
1 yr ago
Self-Experimentation
Share, Please
I've seen a post or two of someone talking about taking dasatinib + quercitin. I've even seen a detailed dosage schedule and mention of a list of compounding pharmacies that I can't find.…
Rob8311
Rob8311
5 yrs ago
5
replies
274
3
Last reply
Peter5.0
5 yrs ago
Self-Experimentation
My 80 year old father's proposed regimen. What do you think?
Hi, I'd appreciate a few moments of your time. This is for my 80 year old father. He takes no prescription meds but is in rough shape due to his age and years of less than ideal lifestyle (which we…
cjacek
cjacek
1 yr ago
17
replies
264
1
Last reply
Spasov
1 yr ago
Self-Experimentation
Senolytic Self-experiments and COVID-19
There is evidence that the TOP2 receptor that the COVID-19 virus uses to enter cells is more prevalent in senescent cells. Also, clearing accumulated senescent cells from the immune system probably…
JGC
Retired Professor of Physics
JGC
3 yrs ago
10
replies
262
1
Last reply
Andrew P K Yap
3 yrs ago
Self-Experimentation
EPIGENETIC MUTATIONS, REVERSAL TO NORMAL
Does anybody know of any studies that suggest ways to revert epigenetic mutations back to normal? Direct or indirect methods. Thanks
Andrew P K Yap
Andrew_P_K_Yap
3 yrs ago
11
replies
261
Last reply
Rhett Barret
3 yrs ago
Self-Experimentation
GDF11 rejuvenation
Has anybody here participated with GDF11 Rejuvenation? Results, experience?
Dan
moderator
skipping my funeral
dantheman
5 yrs ago
4
replies
259
1
Last reply
Dan
moderator
4 yrs ago
Self-Experimentation
sirolimus vehicle
Does anyone have any sources for formulating aqueous solutions of rapamycin? I got my hands on 10g pure powder, and I would like to start the 5mg/week regimen.…
Anna Marie
Anna_Marie
3 yrs ago
6
replies
252
Last reply
Van
3 yrs ago
Self-Experimentation
Biological Age = 32.75y, Chronological Age = 47y: First 2020 measurement
https://michaellustgarten.com/2020/02/14/biological-age-32-75y-chronological-age-47y-first-2020-measurement/
michael lustgarten
michael_lustgarten
4 yrs ago
1
reply
251
1
Last reply
michael lustgarten
3 yrs ago
Self-Experimentation
My Rapamycin Experiment: Male / Early 30s / Non-US Based
Hi, So I'm currently at the early stages of experimenting with Rapamycin, and thought, if I'm going to take an experimental drug, I might as well document the process and see if it can benefit the…
rapa_experimenter
rapa_experimenter
2 yrs ago
8
replies
249
2
Last reply
rapa_experimenter
2 yrs ago
Self-Experimentation
Testosterone Trials
The Testosterone Trials were a set of seven randomized placebo-controlled trials that evaluated the efficacy of testosterone replacement therapy (TRT) in older men with low testosterone levels,…
Michael
Michael.1
2 yrs ago
6
replies
248
1
Last reply
Michael
1 yr ago
Self-Experimentation
Biohackers Perform First Plasma Dilution Experiment on Humans This technique is a human modification of the Conboys' mouse experiments.
https://www.lifespan.io/news/biohackers-perform-first-plasma-dilution-experiment-on-humans/
Larry
Larry.1
3 yrs ago
8
replies
242
Last reply
Spasov
2 yrs ago
Self-Experimentation
Wynn Protocol
Hi everyone, here is a link to my protocol, the "Wynn Protocol". I've 42 years old. My last phenotypic age was -16 years. I'm 5'10" 156 pounds. I've taken a lot of supplements and I've also stopped…
Jimmy2
Jimmy2
2 yrs ago
7
replies
242
2
Last reply
Jimmy2
2 yrs ago
Self-Experimentation
Autophagy / fasting
I've recently become aware of the importance of autophagy in the cells and the ability to promote or trigger this through fasting. Just started a 3 day fast yesterday (I'm doing the apple fast,…
Phoebe Saffold
Phoebe_Saffold
2 yrs ago
3
replies
241
Last reply
Jack Black
2 yrs ago
Self-Experimentation
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