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Self-Experimentation

Share your story of trying or designing a promising age-reversal protocol.

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l-carnitine
https://www.webmd.com/vitamins/ai/ingredientmono-1026/l-carnitine
- Michael
- Michael.1
- 3 yrs ago
- 1reply
- 92
- Last replyMichael3 yrs ago
- Self-Experimentation
Telmisartan
https://thinksteroids.com/steroid-profiles/telmisartan/
- Michael
- Michael.1
- 3 yrs ago
- 84
- Self-Experimentation
"Senolytic Activator" and Extended Fasting …
Gentlefolk, Our fine friends at Life Extension have released a new product, Senolytic Activator. It is a combination of Quercertin and Theaflavins. They intend us to use it weekly as a…
- adonoho
- adonoho
- 6 yrs ago
- 36replies
- 2091
- 6
- Last replyMarc Bauchet3 yrs ago
- Self-Experimentation
Rapamycin and muscle mass
I often hear rapamycin touted as a way of preserving muscle mass but mTOR is vital for muscle hypertrophy? Can anyone explain this apparent contradiction?…
- DAVID W
- DAVID_WOODHOUSE
- 3 yrs ago
- 8replies
- 292
- 1
- Last replyMichael3 yrs ago
- Self-Experimentation
cell metabolism article--that says metformin, resveratrol and rapaymcin dampen the response from good nutrients--Would love to hear thoughts
- linda
- linda
- linda_
- 3 yrs ago
- 2replies
- 99
- Last replylinda3 yrs ago
- Self-Experimentation
Using chelation for cardiovascular health
I wasn't sure if this was an appropriate topic for a longevity discussion. But, with further thought, I figured any process that helps extend my life is appropriate.…
- Jay Galambos
- Jay_Galambos
- 6 yrs ago
- 6replies
- 168
- 3
- Last replyJames3 yrs ago
- Self-Experimentation
Apigenin: An Alternative Way of Boosting NAD+
At the recent Ending Age-Related Diseases 2021 online conference, Dr. Eric Verdin of the Buck Institute gave a talk in which he described the mechanism behind the well-known drop in NAD+ with age,…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- 22replies
- 686
- 5
- Last replyStaffan Olsson3 yrs ago
- Self-Experimentation
Physician in the UK
Hello guys, I hope this is the good section for this. I am hoping to find a medical doctor in the UK that would be open to self experimentation for longevity purpose.…
- Raphael Nicolle
- Raphael_Nicolle
- 4 yrs ago
- 2replies
- 69
- Last replyRaphael Nicolle3 yrs ago
- Self-Experimentation
stem cells---Does anyone have experience with prp + stem cells for bone on bone knee pain? I an considering it but very expensive
- linda
- linda
- linda_
- 3 yrs ago
- 30
- Self-Experimentation
Senolytics
I've just finished my third Senolytic cycle. Fisetin 1500 mgs on 2 consecutihve days repeated one month later Dasatinab 180 mgs on 2 consecutive days + Quercitn 2250 mgs on the same days I also take…
- Charles Grashow
- Charles_Grashow
- 5 yrs ago
- 128replies
- 4283
- 8
- Last replyWil3 yrs ago
- Self-Experimentation
My Rapamycin Experiment: Male / Early 30s / Non-US Based
Hi, So I'm currently at the early stages of experimenting with Rapamycin, and thought, if I'm going to take an experimental drug, I might as well document the process and see if it can benefit the…
- rapa_experimenter
- rapa_experimenter
- 3 yrs ago
- 8replies
- 251
- 2
- Last replyrapa_experimenter3 yrs ago
- Self-Experimentation
Just waiting for the forum Nazi moderators to remove my comments - again
- Michael
- Michael.1
- 3 yrs ago
- 77
- Self-Experimentation
Biohackers Perform First Plasma Dilution Experiment on Humans This technique is a human modification of the Conboys' mouse experiments.
https://www.lifespan.io/news/biohackers-perform-first-plasma-dilution-experiment-on-humans/
- Larry
- Larry.1
- 4 yrs ago
- 8replies
- 248
- Last replySpasov3 yrs ago
- Self-Experimentation
Melatonin - some thoughts
I find melatonin quite interesting not just for its sleep effects, but also for its other effects in terms of cellular health. Hence I have done a video about that.
- John Hemming
- John_Hemming
- 3 yrs ago
- 2replies
- 115
- 2
- Last replyJohn Hemming3 yrs ago
- Self-Experimentation
Targeted clearance of senescent cells using an antibody-drug conjugate against a specific membrane marker
https://phys.org/news/2021-10-antibodies-cells-aging.html?fbclid=IwAR0VjejnoL7OXThHjznaImnlmyL-KTrRcSk3AZqlp_Fn5-cEOBXDJ7iQHww No one knows why some people age worse than others and develop diseases…
- Dan Nave
- Dan_Nave
- updated 3 yrs ago
- 2replies
- 55
- Last replyPaul D Wolf3 yrs ago
- Self-Experimentation
HGLA and GLA as Senolytics
In an interview posted online by Tufts Now, Dr. Christopher Wiley of Tufts University describes his discovery that dihomo-gamma-linoleic acid (DGLA) is a powerful senolytic.…
- JGC
- Retired Professor of Physics
- JGC
- updated 3 yrs ago
- 3replies
- 231
- Last replychuck stanley3 yrs ago
- Self-Experimentation
Wynn Protocol
Hi everyone, here is a link to my protocol, the "Wynn Protocol". I've 42 years old. My last phenotypic age was -16 years. I'm 5'10" 156 pounds. I've taken a lot of supplements and I've also stopped…
- Jimmy2
- Jimmy2
- 3 yrs ago
- 7replies
- 244
- 2
- Last replyJimmy23 yrs ago
- Self-Experimentation
Fisetin for Immune System
I started taking a low dose of Fisetin a little over a year ago. I take about 20 supplements. In the past year I have not been sick once and I have been around many sick people.…
- JOHN
- JOHN.1
- updated 5 yrs ago
- 2replies
- 318
- Last replyCarol Lee3 yrs ago
- Self-Experimentation
Source of pyridoxamine?
Anybody have a source of pyridoxamine for anti-glycation self-experimentation? It is still sold in Europe as a supplement, but was banned in USA since it's being developed as a drug. Thanks
- David
- Davin8r
- 3 yrs ago
- 28
- Self-Experimentation
Epidemiological Studies vs n=1: What's Optimal For Dietary Cholesterol?
https://www.youtube.com/watch?v=eQmPZiW72Yc
- michael lustgarten
- michael_lustgarten
- 3 yrs ago
- 19
- Self-Experimentation
Improving Cellular Health and specifically Vitamin D
I have been doing quite a bit of self-experimentation with a view to improving my cellular health and trying to undo some of the damage that has been done to my cells over the years.…
- John Hemming
- John_Hemming
- 3 yrs ago
- 54
- Self-Experimentation
Anti-Aging Self-Experiment with Epitalon (AEDG)
There is a body of evidence, coming primarily from the publications of Vladimir Kh. Khavinson and his group at the Institute of Bioregulation and Gerontology (IB&G) in Moscow,…
- JGC
- Retired Professor of Physics
- JGC
- 4 yrs ago
- 25replies
- 1293
- 6
- Last replyBurgundy Summer3 yrs ago
- Self-Experimentation
Resveratrol -- value, dose, source?
There is controversy over resveratrol, and its advocates. What is the value of resveratrol as part of an age reversal supplement program? One highly visible individual recommends Resveratrol that is:…
- JohnnyAdamsmoderator
- Mission: Slow and Ultimately Reverse Biological Aging and Age Related Decline for More Years of Healthy Living
- JohnnyAdams
- 5 yrs ago
- 22replies
- 889
- Last replyStevan Lieberman3 yrs ago
- Self-Experimentation
Attempting To Further Reduce Biological Age: hs-CRP
https://www.youtube.com/watch?v=0sUYtkiJEMs
- michael lustgarten
- michael_lustgarten
- 3 yrs ago
- 35
- Self-Experimentation
Replacing Hormones to Optimal Levels
I’ve been experimenting with exogenous testosterone for over 15 years. At almost 73 I have been able to build and keep muscle. I eat a diet high in protein, lower in carbs and healthy fats.…
- Sharon Smith
- Sharon_Smith
- 3 yrs ago
- 27replies
- 606
- 5
- Last replyArizona Kid3 yrs ago
- Self-Experimentation

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