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Self-Experimentation
Share your story of trying or designing a promising age-reversal protocol.
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My story (your suggestions) Dr Arvind Poswal
Hi. I am new here. Would like to know your thoughts. I begin by detailing my major life health points. I think I am a good candidate for knowing the effects of many of the anti-ageing medicines.…
Arvind Poswal
Arvind_Poswal
2 yrs ago
99
2
Self-Experimentation
Self Experimenting: Rapamycin & NAD+ Boosters
How many people are taking sirolimus and NAD+ Boosters (NR and/or NMN)? Do you notice different effects from either? Also, do you cycle the NAD+ Boosters or take them daily?
Thomas G
Thomas_G
3 yrs ago
1
reply
228
Last reply
Mark Rittman
2 yrs ago
Self-Experimentation
Inflammation and time to change
I've often expressed skepticism at folks who take a supplement and are immediately convinced of its efficacy. I've been on a two year journey to reduce inflammation by reducing Omega 6 and…
Paul Beauchemin
Paul_Beauchemin
2 yrs ago
123
1
Self-Experimentation
Ziconotide sources?
Thank you
Michael
Michael.1
2 yrs ago
33
Self-Experimentation
Aspartate Aminotransferase: What's Optimal, And Can It Be Improved?
https://www.youtube.com/watch?v=EO-dB0Hhg20 Papers referenced in the video: Loss of Life Expectancy by 10 Years or More From Elevated Aspartate Aminotransferase:…
michael lustgarten
michael_lustgarten
2 yrs ago
15
Self-Experimentation
Senolytics with DGLA and GLA?
In a comment posted on Fight Aging!, Robert Read says: "There is a specific fatty acid made in small amounts in the body called dihomo-gamma-linoleic acid or DGLA.…
JGC
Retired Professor of Physics
JGC
2 yrs ago
3
replies
142
2
Last reply
chuck stanley
2 yrs ago
Self-Experimentation
Do doctors prescribe rapamycin to people in their 20s?
I'm looking to experiment with Rapamycin. Does anyone have experience with getting it in their 20s?
rapalogical
rapalogical
3 yrs ago
9
replies
303
Last reply
Arizona Kid
2 yrs ago
Self-Experimentation
Mechanism for Immortality
OK guys, here goes. This is controversial so I apologize beforehand. All you need is NMN because it repairs DNA damage and it boots energy via the mitochondria.…
Chan
Chan
4 yrs ago
23
replies
920
Last reply
Chan
2 yrs ago
Self-Experimentation
Red Blood Cells Decline During Aging, But Can Be Increased Through Diet
https://www.youtube.com/watch?v=3JpyDiNxNeE&feature=youtu.be
michael lustgarten
michael_lustgarten
3 yrs ago
5
replies
155
Last reply
Michael
2 yrs ago
Self-Experimentation
Gamma-Linolenic Acid (GLA), Blood Autophagy, and Phenotypic Age
A recent study published in Nature indicates that as mice age, the autophagy mechanism that clears old and damaged red blood cells falters, reducing the effectiveness of their blood circulation.…
JGC
Retired Professor of Physics
JGC
3 yrs ago
22
replies
359
3
Last reply
aribadabar
2 yrs ago
Self-Experimentation
Exercise Mimetics
[Not medical advice or a recommendation. Sharing for information only.] Exercise being something of an anti-aging aid, the idea of exercise mimetics comes up.…
Jack Black
Jack_Black
3 yrs ago
5
replies
160
1
Last reply
Vasiliy
2 yrs ago
Self-Experimentation
Started my D+Q+F Protocol
I was able to purchase dasatinib from this source: https://teamtlr.com/anti-aginglongevity-research/118-senolytix-an-optimized-anti-aging-research-agent.…
SCOTT WEANER
SCOTT_WEANER
2 yrs ago
153
Self-Experimentation
VLDL Increases During Aging, And Is Associated With Adverse Cardiovascular Outcomes
Including 40 blood test measurements for VLDL: https://www.youtube.com/watch?v=NBzWUsfmBc8
michael lustgarten
michael_lustgarten
2 yrs ago
38
Self-Experimentation
New Spermidine Paper: Dietary spermidine improves cognitive function
Full Paper Here: https://www.cell.com/cell-reports/fulltext/S2211-1247(21)00299-0 Highlights Elevated spermidine intake improves cognitive function in flies and mice Dietary spermidine intake…
Brin Chikovski
Brin_Chikovski
3 yrs ago
1
reply
145
Last reply
Brin Chikovski
3 yrs ago
Self-Experimentation
mark t
I was wondering how you made your cream the 2mg in 4oz? 4oz of what? Thank you.
curious
curious
3 yrs ago
9
replies
230
Last reply
Andrew
3 yrs ago
Self-Experimentation
Rapamycin and Blood Pressure Pills
Is anyone here taking Rapamycin along with high blood-pressure pills (Ace Inhibitors and amLODIPine)? I’m curious, as I’ve been doing a lot of research and the combo doesn’t seem all that positive.…
Paula Marie
Paula_Marie
3 yrs ago
3
replies
133
1
Last reply
Paula Marie
3 yrs ago
Self-Experimentation
sirolimus vehicle
Does anyone have any sources for formulating aqueous solutions of rapamycin? I got my hands on 10g pure powder, and I would like to start the 5mg/week regimen.…
Anna Marie
Anna_Marie
3 yrs ago
6
replies
252
Last reply
Van
3 yrs ago
Self-Experimentation
Are we using WAY to low dose of fisetin? 10% vs 50% vs 98%
Hey guys. I just came to the conclusion that we might are using a way to low dose of fisetin. Alot of the sellers use 10% fisetin. This last year ive bought a 98% extract.…
Burgundy Summer
Burgundy_Summer
updated
3 yrs ago
182
1
Self-Experimentation
Quantifying Biological Age: Blood Test #1 in 2021
https://www.youtube.com/watch?v=U0nTtDmCwSQ
michael lustgarten
michael_lustgarten
3 yrs ago
44
Self-Experimentation
Kidney Function Declines During Aging-Can It Be Reversed?
In the video: Data for changes in kidney function during aging, kidney function values that are associated with an increased risk of death for all causes What's my data for kidney function,…
michael lustgarten
michael_lustgarten
3 yrs ago
10
replies
304
Last reply
Edward Meininger
3 yrs ago
Self-Experimentation
Micro-Dosing Lithium for Life Extension - How to Divide 300mg Tablet?
I've been reading the research on how low-dose lithium looks to be helpful in age mitigation as outlined in links below. I want to try it at the level of 5mg to 10mg a day.…
Brin Chikovski
Brin_Chikovski
updated
3 yrs ago
28
replies
431
1
Last reply
aribadabar
3 yrs ago
Self-Experimentation
Epithalon
Anyone inject Epithalon? 1) Any suggestions on both reformulating 50mg Epithalon and daily dose? 2) Anyone have experience mixing in a facial cream? (ALA Mark's rapamycin cream as found all over…
Michael
Michael.1
3 yrs ago
5
replies
174
Last reply
Michael
3 yrs ago
Self-Experimentation
Quantifying Biological Age With Aging.ai: 24 Blood Tests Since 2009
The maximal reduction for biological age when using the biological age calculator, Phenotypic Age, is ~20 years. In other words, if I'm 80 years old and my biomarkers are all reflective of youth,…
michael lustgarten
michael_lustgarten
3 yrs ago
57
Self-Experimentation
High dose nicotinic acid with acetyl-carnitine restores hair color?
I found out that high dose nicotinic acid (3+ grams) with high dose acetyl-carnitine (1+ grams) seems to be able to at least partially restore hair color in my father in his 70s,…
Big Guy
Big_Guy
3 yrs ago
5
replies
450
1
Last reply
Ludovic Debels
3 yrs ago
Self-Experimentation
Is it me or is Apigenin not so hot in this forum
Treatment of cells with apigenin or quercetin inhibits CD38 and promotes an increase in intracellular NAD+ levels. An increased NAD+ level decreases protein acetylation through sirtuin activation. ..…
Andrew P K Yap
Andrew_P_K_Yap
3 yrs ago
21
replies
682
Last reply
Michael
3 yrs ago
Self-Experimentation
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