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Self-Experimentation

Share your story of trying or designing a promising age-reversal protocol.

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NAD+ then Rapamycin?
I have read on this forum that NAD+ and Rapamycin counteract eachother. But it seems NAD+ shows affects in 2 weeks while Rapa takes 10 weeks. My plan is to do a 2 week cycle of SubQ NAD+ then…
- Arizona Kid
- Arizona_Kid
- 3 yrs ago
- 2replies
- 200
- Last replyArizona Kid3 yrs ago
- Self-Experimentation
Scenescent fibroblasts
Hi - first post/new here. I've read with great interest about senolytics and I'm specifically looking for something that could target fibroblasts. I'd found extract of milk thistle flowers that is…
- Suzannah White
- Suzannah_White
- updated 3 yrs ago
- 79
- Self-Experimentation
Interested in Self-experimentation Protocol
Hi Everyone, I'm new to this forum and would like to ask some questions. I apologise if these questions have been asked before, I did a search through the forum but could not find the answers.…
- Basil_dev
- Sonia_Devine
- 3 yrs ago
- 93
- Self-Experimentation
Dietary CD38 Inhibitors: Are They Correlated With Biological Age?
https://www.youtube.com/watch?v=ESCIfQp7z-U
- michael lustgarten
- michael_lustgarten
- 3 yrs ago
- 50
- Self-Experimentation
How to increase the bioavailability of Fisetin
I'm preparing to do a Fisetin senolytic experiment, but I've read on the article from Mayo Clinic ( https://linkinghub.elsevier.com/retrieve/pii/S2352396418303736 ) that the administration mode was…
- JPA
- JPA
- 6 yrs ago
- 110replies
- 6788
- 3
- Last replyRobert Uomini3 yrs ago
- Self-Experimentation
My story (your suggestions) Dr Arvind Poswal
Hi. I am new here. Would like to know your thoughts. I begin by detailing my major life health points. I think I am a good candidate for knowing the effects of many of the anti-ageing medicines.…
- Arvind Poswal
- Arvind_Poswal
- 3 yrs ago
- 100
- 2
- Self-Experimentation
Self Experimenting: Rapamycin & NAD+ Boosters
How many people are taking sirolimus and NAD+ Boosters (NR and/or NMN)? Do you notice different effects from either? Also, do you cycle the NAD+ Boosters or take them daily?
- Thomas G
- Thomas_G
- 4 yrs ago
- 1reply
- 228
- Last replyMark Rittman3 yrs ago
- Self-Experimentation
Inflammation and time to change
I've often expressed skepticism at folks who take a supplement and are immediately convinced of its efficacy. I've been on a two year journey to reduce inflammation by reducing Omega 6 and…
- Paul Beauchemin
- Paul_Beauchemin
- 3 yrs ago
- 124
- 1
- Self-Experimentation
Ziconotide sources?
Thank you
- Michael
- Michael.1
- 3 yrs ago
- 33
- Self-Experimentation
Aspartate Aminotransferase: What's Optimal, And Can It Be Improved?
https://www.youtube.com/watch?v=EO-dB0Hhg20 Papers referenced in the video: Loss of Life Expectancy by 10 Years or More From Elevated Aspartate Aminotransferase:…
- michael lustgarten
- michael_lustgarten
- 3 yrs ago
- 15
- Self-Experimentation
Senolytics with DGLA and GLA?
In a comment posted on Fight Aging!, Robert Read says: "There is a specific fatty acid made in small amounts in the body called dihomo-gamma-linoleic acid or DGLA.…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- 3replies
- 142
- 2
- Last replychuck stanley3 yrs ago
- Self-Experimentation
Do doctors prescribe rapamycin to people in their 20s?
I'm looking to experiment with Rapamycin. Does anyone have experience with getting it in their 20s?
- rapalogical
- rapalogical
- 4 yrs ago
- 9replies
- 322
- Last replyArizona Kid3 yrs ago
- Self-Experimentation
Mechanism for Immortality
OK guys, here goes. This is controversial so I apologize beforehand. All you need is NMN because it repairs DNA damage and it boots energy via the mitochondria.…
- Chan
- Chan
- 5 yrs ago
- 23replies
- 923
- Last replyChan3 yrs ago
- Self-Experimentation
Red Blood Cells Decline During Aging, But Can Be Increased Through Diet
https://www.youtube.com/watch?v=3JpyDiNxNeE&feature=youtu.be
- michael lustgarten
- michael_lustgarten
- 4 yrs ago
- 5replies
- 156
- Last replyMichael3 yrs ago
- Self-Experimentation
Gamma-Linolenic Acid (GLA), Blood Autophagy, and Phenotypic Age
A recent study published in Nature indicates that as mice age, the autophagy mechanism that clears old and damaged red blood cells falters, reducing the effectiveness of their blood circulation.…
- JGC
- Retired Professor of Physics
- JGC
- 4 yrs ago
- 22replies
- 362
- 3
- Last replyaribadabar3 yrs ago
- Self-Experimentation
Exercise Mimetics
[Not medical advice or a recommendation. Sharing for information only.] Exercise being something of an anti-aging aid, the idea of exercise mimetics comes up.…
- Jack Black
- Jack_Black
- 4 yrs ago
- 5replies
- 175
- 1
- Last replyVasiliy3 yrs ago
- Self-Experimentation
Started my D+Q+F Protocol
I was able to purchase dasatinib from this source: https://teamtlr.com/anti-aginglongevity-research/118-senolytix-an-optimized-anti-aging-research-agent.…
- SCOTT WEANER
- SCOTT_WEANER
- 3 yrs ago
- 154
- Self-Experimentation
VLDL Increases During Aging, And Is Associated With Adverse Cardiovascular Outcomes
Including 40 blood test measurements for VLDL: https://www.youtube.com/watch?v=NBzWUsfmBc8
- michael lustgarten
- michael_lustgarten
- 3 yrs ago
- 38
- Self-Experimentation
New Spermidine Paper: Dietary spermidine improves cognitive function
Full Paper Here: https://www.cell.com/cell-reports/fulltext/S2211-1247(21)00299-0 Highlights Elevated spermidine intake improves cognitive function in flies and mice Dietary spermidine intake…
- Brin Chikovski
- Brin_Chikovski
- 4 yrs ago
- 1reply
- 146
- Last replyBrin Chikovski4 yrs ago
- Self-Experimentation
mark t
I was wondering how you made your cream the 2mg in 4oz? 4oz of what? Thank you.
- curious
- curious
- 4 yrs ago
- 9replies
- 237
- Last replyAndrew4 yrs ago
- Self-Experimentation
Rapamycin and Blood Pressure Pills
Is anyone here taking Rapamycin along with high blood-pressure pills (Ace Inhibitors and amLODIPine)? I’m curious, as I’ve been doing a lot of research and the combo doesn’t seem all that positive.…
- Paula Marie
- Paula_Marie
- 4 yrs ago
- 3replies
- 134
- 1
- Last replyPaula Marie4 yrs ago
- Self-Experimentation
sirolimus vehicle
Does anyone have any sources for formulating aqueous solutions of rapamycin? I got my hands on 10g pure powder, and I would like to start the 5mg/week regimen.…
- Anna Marie
- Anna_Marie
- 4 yrs ago
- 6replies
- 254
- Last replyVan4 yrs ago
- Self-Experimentation
Are we using WAY to low dose of fisetin? 10% vs 50% vs 98%
Hey guys. I just came to the conclusion that we might are using a way to low dose of fisetin. Alot of the sellers use 10% fisetin. This last year ive bought a 98% extract.…
- Burgundy Summer
- Burgundy_Summer
- updated 4 yrs ago
- 186
- 1
- Self-Experimentation
Quantifying Biological Age: Blood Test #1 in 2021
https://www.youtube.com/watch?v=U0nTtDmCwSQ
- michael lustgarten
- michael_lustgarten
- 4 yrs ago
- 44
- Self-Experimentation
Kidney Function Declines During Aging-Can It Be Reversed?
In the video: Data for changes in kidney function during aging, kidney function values that are associated with an increased risk of death for all causes What's my data for kidney function,…
- michael lustgarten
- michael_lustgarten
- 4 yrs ago
- 10replies
- 308
- Last replyEdward Meininger4 yrs ago
- Self-Experimentation

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