EPIGENETIC MUTATIONS, REVERSAL TO NORMAL

Does anybody know of any studies that suggest ways to revert epigenetic mutations back to normal? Direct or indirect methods. Thanks

Quantifying Phenotypic Age: Blood Test Measurement #3 in 2020

Biological Age = 32.75y, Chronological Age = 47y: First 2020 measurement

https://michaellustgarten.com/2020/02/14/biological-age-32-75y-chronological-age-47y-first-2020-measurement/

Paul's Anti-Aging Efforts

Preparing for a LONG FUTURE, here are the prescriptions and supplements I take to STOP or REVERSE AGING, with the blessings of my doctors. After each one are the number of Web sites mentioning them,…

32 years old. Is self-experimentation right for me?

So, as the title says, I'm 32 years old. I'm very interested in longevity research and I would like to try some of these methods to help slow my aging.…

Senolytic Self-experiments and COVID-19

There is evidence that the TOP2 receptor that the COVID-19 virus uses to enter cells is more prevalent in senescent cells. Also, clearing accumulated senescent cells from the immune system probably…

Life is an experiment

I've been working on "me" for years and lately I've started to look beyond diet, exercise, lifestyle, sleep etc. Until now I've only been supplementing with creatine, fish oil,…

Did anyone experience acute inflammation after senolytics?

Hello, I have Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. It is a condition that involves chronic inflammation. I tried 3 days of high dose Fisetin the last 3 days (1000mg/day).…

Trehalose

Has anybody researched or tried trehalose to kill senescent cells? I have just come across it in the literature, apparently it stimulates AMPK like Metformin does,…

7 months taking rapamune

I have lived in Mexico for 9 years. After catching an article about rapamycin I found that I could get it here, without a prescription. Farmalisto in Mexico City to be exact but they do not ship to…

Lisinopril and Self Experimentation.

Has anyone had any problems with metformin whilst on Lisinopril drug ? Possible interactions are mentioned on advice sites. Dasatinib and Lisinopril also get a mention in this regard.…

Hyperbaric oxygen therapy

Hi, What is hyperbaric oxygen therapy and how it will helpful for patient? Researcher Shai Efrati share complete information regarding such question. Hope this will help many patients.

Here is another Doctor Who prescribes rapamycin in Las Vegas.

I thought I would provide the name of my Doctor who does prescribes rapamycin but his practice is different from Dr. Green in New York. I have found him to be very knowledgeable and extremely…

LDL-C reduction with diet and supplements (no statins)

Hi everyone, I recently came across some interesting videos about the optimal levels of LDL-C at the website, http://plantpositive.com/ . The author of the videos includes screenshots of the…

Which Dasatinib and Quercetin dosing regimen for longevity?

I have read about two different dosing regimens: 3 consecutive daily doses a week repeated for three weeks based on weight at a 1 to 10 ration based on weight (IE: for a 165lb person,…

Rapamycin and APOE4 gene.

According to Dr. Alan Green, Rapamycin is particularly effective in APOE4 carriers, ameliorating the effects of atherosclerosis and Alzheimer's. Does anyone have any experience with either of these…

DMSO for Increased Flavenoid Solubility and Bioavailability?

The problem with the bio-delivery of senolytic flavenoids like Quercetin and Fisetin is that they are insoluble in water. Therefore, there is a good chance that if taken orally,…

Dasapro Dasatinib from IAS Reliable

Hello, Does anyone have any reason to think the Dasapro branded Dasatinib from IAS would not be reliable? Do they have a good reputation and do they do third party testing of their products?…

Dasatinib testing -- Information about ordering testing for dasatinib and rapamycin, and other compounds

Information about ordering testing for purity and content of dasatinib and rapamycin, and other compounds, has been created. That info, and a lot more that's needed for their safe use,…

Green tea and green tea extracts

Green tea benefits (and how to get them).

Weekly Rapamycin/Sirolimus Therapy and Diarrhea?

Is anyone else experiencing chronic diarrhea as a result of weekly dosing (6mg/week) of Sirolimus? If so, have you found any method of dealing with it other than stopping?

Hyperbaric Oxygen Therapy

Hi there, Are you heard about HBOT. HBOT helps wound healing by bringing oxygen-rich plasma to tissue starved for oxygen. Wound injuries damage the body's blood vessels,…

Suppliers for Metformin(Glycomet), Rapamycin(Sirolimus) and Dasatinib(Sprycel)

For Metformin(Glycomet) https://www.alldaychemist.com/glycomet-500mg-sr.html For Rapamycin(Sirolimus) https://www.alldaychemist.com/siromus-1mg.html For Dasatinib(Sprycel) https://www.bonhoahealth.…

Albearth’s Self-Experimentation

My self-experimentation dates back to 2008 and continues to this day. These experiments have been effective and have helped my entire body. As much as this self-experimentation has done me so well,…

Reversing arteriosclerotic disease

I think the forum could benefit from the topic “reversing arteriosclerotic disease”. This since arteriosclerosis is one of the main culprits that shorten the life of many human beings.…