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Self-Experimentation

Share your story of trying or designing a promising age-reversal protocol.

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Biological Age = 32.75y, Chronological Age = 47y: First 2020 measurement
https://michaellustgarten.com/2020/02/14/biological-age-32-75y-chronological-age-47y-first-2020-measurement/
- michael lustgarten
- michael_lustgarten
- 5 yrs ago
- 1reply
- 251
- 1
- Last replymichael lustgarten4 yrs ago
- Self-Experimentation
Paul's Anti-Aging Efforts
Preparing for a LONG FUTURE, here are the prescriptions and supplements I take to STOP or REVERSE AGING, with the blessings of my doctors. After each one are the number of Web sites mentioning them,…
- Paul Mason
- Paul_Mason
- 6 yrs ago
- 12replies
- 1380
- 4
- Last replySimon Lee4 yrs ago
- Self-Experimentation
32 years old. Is self-experimentation right for me?
So, as the title says, I'm 32 years old. I'm very interested in longevity research and I would like to try some of these methods to help slow my aging.…
- Sara V
- Sara_V
- 5 yrs ago
- 6replies
- 336
- Last replyFairy8i85 yrs ago
- Self-Experimentation
Senolytic Self-experiments and COVID-19
There is evidence that the TOP2 receptor that the COVID-19 virus uses to enter cells is more prevalent in senescent cells. Also, clearing accumulated senescent cells from the immune system probably…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- 10replies
- 263
- 1
- Last replyAndrew P K Yap5 yrs ago
- Self-Experimentation
Life is an experiment
I've been working on "me" for years and lately I've started to look beyond diet, exercise, lifestyle, sleep etc. Until now I've only been supplementing with creatine, fish oil,…
- Dave C
- David_Clubine
- 5 yrs ago
- 2replies
- 186
- 2
- Last replyFairy8i85 yrs ago
- Self-Experimentation
Did anyone experience acute inflammation after senolytics?
Hello, I have Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. It is a condition that involves chronic inflammation. I tried 3 days of high dose Fisetin the last 3 days (1000mg/day).…
- Phoenix
- phoenix
- 6 yrs ago
- 7replies
- 632
- 1
- Last replyAndrew P K Yap5 yrs ago
- Self-Experimentation
Trehalose
Has anybody researched or tried trehalose to kill senescent cells? I have just come across it in the literature, apparently it stimulates AMPK like Metformin does,…
- Koo
- Koo
- 5 yrs ago
- 1reply
- 95
- Last replyAndrew P K Yap5 yrs ago
- Self-Experimentation
7 months taking rapamune
I have lived in Mexico for 9 years. After catching an article about rapamycin I found that I could get it here, without a prescription. Farmalisto in Mexico City to be exact but they do not ship to…
- Dale Duke
- Dale_Duke
- 5 yrs ago
- 1reply
- 243
- 3
- Last replyuzoma iwuagwu5 yrs ago
- Self-Experimentation
Lisinopril and Self Experimentation.
Has anyone had any problems with metformin whilst on Lisinopril drug ? Possible interactions are mentioned on advice sites. Dasatinib and Lisinopril also get a mention in this regard.…
- Seaside
- Seaside
- 5 yrs ago
- 10replies
- 130
- Last replyMSS5 yrs ago
- Self-Experimentation
Hyperbaric oxygen therapy
Hi, What is hyperbaric oxygen therapy and how it will helpful for patient? Researcher Shai Efrati share complete information regarding such question. Hope this will help many patients.
- Cherith
- Cherith
- 5 yrs ago
- 1reply
- 115
- Last replyMark Thimineur5 yrs ago
- Self-Experimentation
Here is another Doctor Who prescribes rapamycin in Las Vegas.
I thought I would provide the name of my Doctor who does prescribes rapamycin but his practice is different from Dr. Green in New York. I have found him to be very knowledgeable and extremely…
- John Mcgough
- John_Mcgough
- 5 yrs ago
- 132
- 1
- Self-Experimentation
LDL-C reduction with diet and supplements (no statins)
Hi everyone, I recently came across some interesting videos about the optimal levels of LDL-C at the website, http://plantpositive.com/ . The author of the videos includes screenshots of the…
- Maximus Peto
- Researcher, website & forum admin
- Maximus
- 6 yrs ago
- 14replies
- 490
- 2
- Last replyAjax5 yrs ago
- Self-Experimentation
Which Dasatinib and Quercetin dosing regimen for longevity?
I have read about two different dosing regimens: 3 consecutive daily doses a week repeated for three weeks based on weight at a 1 to 10 ration based on weight (IE: for a 165lb person,…
- Randall James
- Randall_James
- 5 yrs ago
- 8replies
- 543
- 2
- Last replyFlorin5 yrs ago
- Self-Experimentation
Rapamycin and APOE4 gene.
According to Dr. Alan Green, Rapamycin is particularly effective in APOE4 carriers, ameliorating the effects of atherosclerosis and Alzheimer's. Does anyone have any experience with either of these…
- Jonathan Horwitz
- Jonathan_Horwitz
- 5 yrs ago
- 12replies
- 324
- Last replyMAC5 yrs ago
- Self-Experimentation
DMSO for Increased Flavenoid Solubility and Bioavailability?
The problem with the bio-delivery of senolytic flavenoids like Quercetin and Fisetin is that they are insoluble in water. Therefore, there is a good chance that if taken orally,…
- JGC
- Retired Professor of Physics
- JGC
- 6 yrs ago
- 3replies
- 429
- 1
- Last replyAsclepius5 yrs ago
- Self-Experimentation
Dasapro Dasatinib from IAS Reliable
Hello, Does anyone have any reason to think the Dasapro branded Dasatinib from IAS would not be reliable? Do they have a good reputation and do they do third party testing of their products?…
- Phoenix
- phoenix
- 5 yrs ago
- 1reply
- 151
- 1
- Last replyMark McGovern5 yrs ago
- Self-Experimentation
Dasatinib testing -- Information about ordering testing for dasatinib and rapamycin, and other compounds
Information about ordering testing for purity and content of dasatinib and rapamycin, and other compounds, has been created. That info, and a lot more that's needed for their safe use,…
- JohnnyAdamsmoderator
- Mission: Slow and Ultimately Reverse Biological Aging and Age Related Decline for More Years of Healthy Living
- JohnnyAdams
- 5 yrs ago
- 2replies
- 131
- 1
- Last replyMaximus Peto5 yrs ago
- Self-Experimentation
Green tea and green tea extracts
Green tea benefits (and how to get them).
- Staffan Olsson
- Staffan_Olsson
- 5 yrs ago
- 43replies
- 813
- 1
- Last replyKarl5 yrs ago
- Self-Experimentation
Weekly Rapamycin/Sirolimus Therapy and Diarrhea?
Is anyone else experiencing chronic diarrhea as a result of weekly dosing (6mg/week) of Sirolimus? If so, have you found any method of dealing with it other than stopping?
- Jason Frey
- Jason_Frey
- 5 yrs ago
- 6replies
- 254
- Last replyJason Frey5 yrs ago
- Self-Experimentation
Hyperbaric Oxygen Therapy
Hi there, Are you heard about HBOT. HBOT helps wound healing by bringing oxygen-rich plasma to tissue starved for oxygen. Wound injuries damage the body's blood vessels,…
- Cherith
- Cherith
- 5 yrs ago
- 60
- Self-Experimentation
Suppliers for Metformin(Glycomet), Rapamycin(Sirolimus) and Dasatinib(Sprycel)
For Metformin(Glycomet) https://www.alldaychemist.com/glycomet-500mg-sr.html For Rapamycin(Sirolimus) https://www.alldaychemist.com/siromus-1mg.html For Dasatinib(Sprycel) https://www.bonhoahealth.…
- Patrick McHargue
- Patrick_McHargue
- 5 yrs ago
- 224
- 1
- Self-Experimentation
Albearth’s Self-Experimentation
My self-experimentation dates back to 2008 and continues to this day. These experiments have been effective and have helped my entire body. As much as this self-experimentation has done me so well,…
- Albearth Reyes
- Albearth_Reyes
- 5 yrs ago
- 140
- Self-Experimentation
Reversing arteriosclerotic disease
I think the forum could benefit from the topic “reversing arteriosclerotic disease”. This since arteriosclerosis is one of the main culprits that shorten the life of many human beings.…
- Staffan Olsson
- Staffan_Olsson
- 5 yrs ago
- 11replies
- 415
- 3
- Last replyStaffan Olsson5 yrs ago
- Self-Experimentation
Metformin: worth it? and what to expect
Hello all. I got my Doctor to give me a prescription for Metformin. I have read about its possible age-reversing effects, but I have also read about some possible significant side effects,…
- Jeff Bennion
- Jeff_Bennion
- updated 6 yrs ago
- 35replies
- 1677
- 1
- Last replyCherith5 yrs ago
- Self-Experimentation
Kaufmann Protocol Analysis
Dr. Sandra Kaufman, an MD anesthesiologist with an interest in aging, wrote a 2017 book entitled The Kaufmann Protocol: Why We Age and How to Stop It, in which she describes her approach to…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- 9replies
- 323
- 2
- Last replyDanmoderator5 yrs ago
- Self-Experimentation

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