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Self-Experimentation

Share your story of trying or designing a promising age-reversal protocol.

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Should you get a micronutrient test?
Imagine my excitement as the moment finally arrived - the comprehensive results from my 15 vials of blood and four detailed blood tests that I completed at NextHealth arrived in my inbox.…
- Dr Nick Engerer
- The Longevity Blog
- Dr_Nick_Engerer
- 5 yrs ago
- 1reply
- 89
- Last replyKarl5 yrs ago
- Self-Experimentation
Relaxin (RLX)
Hi Everyone, Has anyone looked at sourcing & using RLX? I've had an AVR operation 8 months ago & my EF has gone from 67 (12 months pre-op) to 55 (pre-op) to 35 (post-op).…
- Trevor Bingley
- Trevor_Bingley
- 5 yrs ago
- 40
- Self-Experimentation
Ursolic acid
I am curious about this substance - Ursolic acid. I wonder if there are people in here that have first hand experience from the use of Ursolic acid. I post a link to a review from 2018.…
- Staffan Olsson
- Staffan_Olsson
- 5 yrs ago
- 64
- Self-Experimentation
enhancing NAD precursor effectiveness
Therapeutic doses of NR and NMN in studies are usually much larger than the suggested amount on the label. Chromadex NR studies usually use a gram or more of the stuff,…
- Ajax
- Ajax
- 5 yrs ago
- 6replies
- 390
- 3
- Last replyDorian Gray5 yrs ago
- Self-Experimentation
Late life metformin treatment limits cell survival and shortens lifespan by triggering an aging-associated failure of energy metabolism
Not sure how to take this. Anyone more knowledgeable care to comment? https://www.biorxiv.org/content/10.1101/863357v1
- Patrick McHargue
- Patrick_McHargue
- 5 yrs ago
- 3replies
- 164
- Last replyDavid H5 yrs ago
- Self-Experimentation
Telomerase Activators
I couldn’t find discussions about the available telomerase activators such as Isegenesis, TA-65, and Defytime Aging Care Capsules (previously named TAM-818,…
- David H
- David_Hanson
- 5 yrs ago
- 2replies
- 235
- Last replyKarl5 yrs ago
- Self-Experimentation
Serrapeptase headaches
Serrapeptase and proteolytic enzymes cause headaches over a very long period of time. I think the headaches may be caused primariy by the brain's attempts to get rid of the debris left behind after…
- Paul B
- Paul_B
- 5 yrs ago
- 1reply
- 90
- Last replyDIANE B5 yrs ago
- Self-Experimentation
GDF11 rejuvenation
Has anybody here participated with GDF11 Rejuvenation? Results, experience?
- Danmoderator
- skipping my funeral
- dantheman
- 6 yrs ago
- 4replies
- 263
- 1
- Last replyDanmoderator5 yrs ago
- Self-Experimentation
Sources for Metformin?
Suggestions? The best source is via your GP. I have script for Metformin due to an undiscovered elevated glucose (check yours first thing in the morning,…
- Danmoderator
- skipping my funeral
- dantheman
- updated 5 yrs ago
- 27replies
- 1138
- 2
- Last replyMermaid5 yrs ago
- Self-Experimentation
Ferulic acid
How to use ferulic acid and where to buy ferulic acid as supplement for oral use? My plan is to try Ferulic acid and EGCG (Green tea). My aim for this experiment is to see if this combo can clear…
- Staffan Olsson
- Staffan_Olsson
- 6 yrs ago
- 1reply
- 98
- Last replyStaffan Olsson5 yrs ago
- Self-Experimentation
Beacon pharmaceuticals Ltd
I wonder if there is someone in here that has experience of dasatinib bought directly from Beacon pharmaceuticals Ltd, Bangladesh. https://www.beaconpharma.com.bd/?attachment_id=15948 https://en.…
- Staffan Olsson
- Staffan_Olsson
- 5 yrs ago
- 73
- Self-Experimentation
Dasatinib from Bon Hoa
A couple weeks ago, I placed an order for Lucius Dasatinib from Bon Hoa. So far, I've taken 200 mg on two consecutive days. It had zero effect on me...no nausea, no tiredness, nada.…
- Kevin A
- Valued_Customer
- 5 yrs ago
- 23replies
- 238
- Last replyRobH5 yrs ago
- Self-Experimentation
Biological Age = 31.3y, Chronological Age = 46y
https://michaellustgarten.com/2019/11/01/biological-age-31-3y-chronological-age-46y/
- michael lustgarten
- michael_lustgarten
- 5 yrs ago
- 168
- Self-Experimentation
What biomarkers and objective measures for results of your age management therapies do you have?
Who has before and after biomarker and/or objective measurement evidence demonstrating the effectiveness of any aging intervention therapy in humans? Measures might include: DNA methylation,…
- JohnnyAdamsmoderator
- Mission: Slow and Ultimately Reverse Biological Aging and Age Related Decline for More Years of Healthy Living
- JohnnyAdams
- 5 yrs ago
- 1reply
- 79
- Last replyDanmoderator5 yrs ago
- Self-Experimentation
Christine's Self experiment
I'm going to test a combination of Rapamycin, Q+T, Metformin and Nicotinamide Riboside. I'm a 38 year old woman and this is what I gather to be a full set of supplements for the 35-55 age group.…
- Christine
- Christine
- 5 yrs ago
- 1reply
- 178
- 1
- Last replyChristine5 yrs ago
- Self-Experimentation
Optimizing Biological Age: Albumin
https://michaellustgarten.com/2019/09/22/optimizing-serum-levels-of-albumin-data-from-20-blood-tests/
- michael lustgarten
- michael_lustgarten
- 5 yrs ago
- 79
- Self-Experimentation
The conventional CVD/lipid hypothesis: challenged
The conventional mainstream lipid hypothesis suggests high cholesterol is directly associated with elevated CVD risk. High plasma cholesterol diffuses into the endothelial space via the LUMEN,…
- MAC
- MAC
- 5 yrs ago
- 2replies
- 72
- 1
- Last replyMAC5 yrs ago
- Self-Experimentation
Phosphatidylcholine
Not a lot about Phosphatidylcholine supplementation. Ray Kurzweil is a huge fan as stated in his Transcend book, see that for the why's and wherefores (basically you stop producing it as you get…
- Danmoderator
- skipping my funeral
- dantheman
- 6 yrs ago
- 1reply
- 228
- 1
- Last replyMAC5 yrs ago
- Self-Experimentation
Did this paper about D + Q and tumorigenesis concern anyone here?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218402/ Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death, which develops in the context of fibrosis and cirrhosis caused by…
- Phoenix
- phoenix
- 5 yrs ago
- 4replies
- 154
- Last replyDanmoderator5 yrs ago
- Self-Experimentation
immediate release Metformin (irM) possible side effect: bladder/ prostate irritation
I started taking metformin about 1.5 months ago [2x500mg/day] and have noticed an increased urge to urinate. my bladder or prostate, possibly both, seems to react in a very bad way.…
- Cristian Lapusan
- Cristian_Lapusan
- updated 6 yrs ago
- 1reply
- 113
- Last replyShauna5 yrs ago
- Self-Experimentation
Young plasma treatments in Tampa, Florida
My name is Howard Chipman MD and I have been treating patients with young plasma for anti-aging, dementia and other age related disorders for over a year with good results.…
- Dr. Chipman
- Dr_Chipman
- 7 yrs ago
- 3replies
- 565
- 4
- Last replyDaniel Stephenson5 yrs ago
- Self-Experimentation
The purity of Lucidias-brand Dasatinib
Last year I obtained a 60-tablet bottle of 50 mg Lucidias-brand Dasatinib from BonHoa Pharmacy in New Deli, India, link https://www.bonhoa.com. It seems to be manufactured by Lucius Pharmaceuticals…
- JGC
- Retired Professor of Physics
- JGC
- 6 yrs ago
- 12replies
- 475
- 5
- Last replyLouise B Andrew5 yrs ago
- Self-Experimentation
Rapamycin
I have done bio identical hormones for 3 1/2 months before I start Rapamycin. Do I take 5 mg once a week for 3 months and then take a month off and start again?
- Suzanne
- Suzanne
- 5 yrs ago
- 5replies
- 297
- Last replyLarry5 yrs ago
- Self-Experimentation
Monitoring Senescent Cell Clearance with Cytokine Levels
Many of us have been attempting to clear our senescent cells with large senolytic doses of Fisetin and/or Dasatinib plus Quercetin. There have been many anecdotal reports of "feeling better" or…
- JGC
- Retired Professor of Physics
- JGC
- 6 yrs ago
- 20replies
- 515
- 2
- Last replyDan Nave6 yrs ago
- Self-Experimentation
Rapamycin Side Effect
Just read a recent addition to Dr. Green's site. I'll just post part of what he says. I don't get the impression he thinks it is a reason to stop treating, but important to be aware of.…
- Rob8311
- Rob8311
- 6 yrs ago
- 67replies
- 1467
- 3
- Last replyVincent Stona6 yrs ago
- Self-Experimentation

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