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Self-Experimentation

Share your story of trying or designing a promising age-reversal protocol.

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Micro-Dosing Lithium for Life Extension - How to Divide 300mg Tablet?
I've been reading the research on how low-dose lithium looks to be helpful in age mitigation as outlined in links below. I want to try it at the level of 5mg to 10mg a day.…
- Brin Chikovski
- Brin_Chikovski
- updated 4 yrs ago
- 28replies
- 453
- 1
- Last replyaribadabar4 yrs ago
- Self-Experimentation
Epithalon
Anyone inject Epithalon? 1) Any suggestions on both reformulating 50mg Epithalon and daily dose? 2) Anyone have experience mixing in a facial cream? (ALA Mark's rapamycin cream as found all over…
- Michael
- Michael.1
- 4 yrs ago
- 5replies
- 209
- Last replyMichael4 yrs ago
- Self-Experimentation
Quantifying Biological Age With Aging.ai: 24 Blood Tests Since 2009
The maximal reduction for biological age when using the biological age calculator, Phenotypic Age, is ~20 years. In other words, if I'm 80 years old and my biomarkers are all reflective of youth,…
- michael lustgarten
- michael_lustgarten
- 4 yrs ago
- 57
- Self-Experimentation
High dose nicotinic acid with acetyl-carnitine restores hair color?
I found out that high dose nicotinic acid (3+ grams) with high dose acetyl-carnitine (1+ grams) seems to be able to at least partially restore hair color in my father in his 70s,…
- Big Guy
- Big_Guy
- 4 yrs ago
- 5replies
- 479
- 1
- Last replyLudovic Debels4 yrs ago
- Self-Experimentation
Is it me or is Apigenin not so hot in this forum
Treatment of cells with apigenin or quercetin inhibits CD38 and promotes an increase in intracellular NAD+ levels. An increased NAD+ level decreases protein acetylation through sirtuin activation. ..…
- Andrew P K Yap
- Andrew_P_K_Yap
- 4 yrs ago
- 21replies
- 704
- Last replyMichael4 yrs ago
- Self-Experimentation
Quantifying Biological Age: Blood Test #6 in 2020
Discussed in the video: What's my biological age on blood test #6 in 2020? What's my average biological age for 2020, and how does it compare with 2019? Are there links between calorie intake,…
- michael lustgarten
- michael_lustgarten
- 4 yrs ago
- 38
- Self-Experimentation
Dogs and cats and people
I am learning something new every day. https://www.purinainstitute.com/can-summit/can-2018/new-insights-into-getting-older This has helped me understand what I read here better.
- Jennifer Smith
- We are all responsible for our own health, wealth, and happiness
- Jennifer_Smith
- 4 yrs ago
- 68
- Self-Experimentation
Neutrophils, Lymphocytes, Monocytes: What’s Optimal For Health And Longevity?
For those who track their WBC differentials, here's my latest video about what's optimal for neutrophils, lymphocytes, and monocytes in terms of health and longevity: https://www.youtube.…
- michael lustgarten
- michael_lustgarten
- updated 4 yrs ago
- 52
- 1
- Self-Experimentation
Can any meaningful conclusions of efficacy/harm ever be drawn form individual experience/"self experimentation"?
Hi. This post might irritate, but I mean well. It's prompted by a useful article I read this morning...about the nocebo effect with statin's. https://www.nejm.org/doi/full/10.…
- Steve Roedde
- Steve_Roedde
- 4 yrs ago
- 22replies
- 240
- Last replyJohn Mcgough4 yrs ago
- Self-Experimentation
Finished the First 3 Protocol Steps
I an 72 and have been taking metformin (twice a day but recently increased to 3 times a day) for 5 years. I recently completed 6 patches of NAD+. I also have just taken 2 doses of quercetin and…
- Bernie
- Bernie_Singer
- 6 yrs ago
- 8replies
- 428
- 4
- Last replyRoss Barker4 yrs ago
- Self-Experimentation
HDL: What's Optimal For Minimizing Disease Risk And Maximizing Longevity?
Meta-analysis for the association between HDL with all-cause mortality risk has identified HDL levels 55 - 60 mg/dL range as optimal. However, that data includes subjects up to 85y-in the video,…
- michael lustgarten
- michael_lustgarten
- 4 yrs ago
- 60
- 2
- Self-Experimentation
Tracking progress of my experiment
Hi everyone, I wanted to try a self experiment to see if diet and exercise had an effect on my biological age. It has been a while and I wanted to check my progress,…
- Dave A
- Dave_A
- 4 yrs ago
- 5replies
- 135
- Last replyMichael4 yrs ago
- Self-Experimentation
Quantifying Biological Age: Blood Test #5 in 2020
- michael lustgarten
- michael_lustgarten
- 4 yrs ago
- 95
- Self-Experimentation
Quercetin recomendations
I have just ordered some Dasatinib using the link in the other thread here. I have started to look to get Quercetin as well and I see many options to order it online.…
- Jeff Fuja
- Jeff_Fuja
- 5 yrs ago
- 20replies
- 593
- Last replyGleb Merkurev4 yrs ago
- Self-Experimentation
Biological Age Test #4 in 2020: Getting Better or Getting Worse?
- michael lustgarten
- michael_lustgarten
- 4 yrs ago
- 11replies
- 226
- Last replyMAC4 yrs ago
- Self-Experimentation
RFID
Under the guise of self experimentation, everything you're taking, could be monitored; transmitting back. And, you're last man on the totem pole. I've been around long enough to have voted for…
- Michael
- Michael.1
- 4 yrs ago
- 39
- Self-Experimentation
Bkcaffee's experiment experience
I just received my dasatinib (70 mg ). Before I start taking it I'm wanting to contact a dr in the area (alabama) for review. In the meantime I'm gathering info to do this right.…
- Brandon Caffee
- Brandon_Caffee
- updated 4 yrs ago
- 2replies
- 97
- Last replyJimmy4 yrs ago
- Self-Experimentation
Rapamycin self-experimentation
I've just begun a 10 week self-experimentation with RapaPro rapamycin. I'll be taking 5 mg once a week, which is roughly the dose that Dr. Alan Green recommends on the high side and seems to be…
- Tam
- Tam
- 5 yrs ago
- 74replies
- 3725
- 5
- Last replyLudovic Debels4 yrs ago
- Self-Experimentation
transplant patients
do transplant patients receive antiaging benefits or do they have negative effects on aging?
- curious
- curious
- 4 yrs ago
- 32
- Self-Experimentation
Sources for NMN or NAD
it has been a while since anyone has posted sources for NMN. Anyone find any reliable sources at a reasonable price? Right now I buy from Amazon. Double Wood Supplements 30 grams in powder for $130.…
- ssny. sotero
- Marketing and Visual Impact Display Specialist
- sandra_sotero
- 4 yrs ago
- 3replies
- 236
- Last replyDavid H4 yrs ago
- Self-Experimentation
Can Senolytic drug cure Chronic kidney disease ?
Could you help to advise about senolytic drug and CKD ?
- PuRi
- PuRi
- 4 yrs ago
- 2replies
- 103
- Last replyhellscreamer4 yrs ago
- Self-Experimentation
liposomal Fisetin
Wondering if anyone has heard of this? Supposedly much better absorption, but I would have no idea how to dose it... https://alivebynature.com/product/lsg-fisetin-liposomal-sublingual-gel/
- Robin Maisel
- Robin_Maisel
- 4 yrs ago
- 2replies
- 411
- Last replyEndless4 yrs ago
- Self-Experimentation
Phosphatidylcholine IV
Ray Kurzweil is a fan of Phosphatidylcholine, and seems to be alone in this. Bill and others don't make much truck with it AFAIK. Ray has said he does both IV's and oral supplementation.…
- Danmoderator
- skipping my funeral
- dantheman
- 6 yrs ago
- 19replies
- 510
- 1
- Last replygarland4 yrs ago
- Self-Experimentation
EPIGENETIC MUTATIONS, REVERSAL TO NORMAL
Does anybody know of any studies that suggest ways to revert epigenetic mutations back to normal? Direct or indirect methods. Thanks
- Andrew P K Yap
- Andrew_P_K_Yap
- 5 yrs ago
- 11replies
- 264
- Last replyRhett Barret4 yrs ago
- Self-Experimentation
Quantifying Phenotypic Age: Blood Test Measurement #3 in 2020
- michael lustgarten
- michael_lustgarten
- updated 4 yrs ago
- 59
- Self-Experimentation

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