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Self-Experimentation
Share your story of trying or designing a promising age-reversal protocol.
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GlyNAC
Has anyone tried Glycine/N-acetylcysteine? It appears to have amazing effects on age reversal. Glycine and N‐acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency,…
Qimin You
Qimin_You
3 yrs ago
103
replies
5295
3
Last reply
martino lorenzon
10 mths ago
Self-Experimentation
Calorie Restriction, Eat Once Every Other Day (EOD Diet)
I'm thinking about doing this. I'm not sure if I will have the will power to do so. The EOD Diet will reduce my calorie intake by more than 50%. My goal is to reduce my epigenetic age.…
Jimmy
Jim_N
updated
3 yrs ago
12
replies
306
Last reply
Michael
2 yrs ago
Self-Experimentation
Gamma-Linolenic Acid (GLA), Blood Autophagy, and Phenotypic Age
A recent study published in Nature indicates that as mice age, the autophagy mechanism that clears old and damaged red blood cells falters, reducing the effectiveness of their blood circulation.…
JGC
Retired Professor of Physics
JGC
3 yrs ago
22
replies
359
3
Last reply
aribadabar
2 yrs ago
Self-Experimentation
Anti-Aging Self-Experiment with Epitalon (AEDG)
There is a body of evidence, coming primarily from the publications of Vladimir Kh. Khavinson and his group at the Institute of Bioregulation and Gerontology (IB&G) in Moscow,…
JGC
Retired Professor of Physics
JGC
3 yrs ago
25
replies
1192
6
Last reply
Burgundy Summer
2 yrs ago
Self-Experimentation
Are we using WAY to low dose of fisetin? 10% vs 50% vs 98%
Hey guys. I just came to the conclusion that we might are using a way to low dose of fisetin. Alot of the sellers use 10% fisetin. This last year ive bought a 98% extract.…
Burgundy Summer
Burgundy_Summer
updated
3 yrs ago
182
1
Self-Experimentation
Quantifying Biological Age: Blood Test #1 in 2021
https://www.youtube.com/watch?v=U0nTtDmCwSQ
michael lustgarten
michael_lustgarten
3 yrs ago
44
Self-Experimentation
linda
has anyone purchased 1 rapacan --sirolimus manufactured by bicon from varun medicals?? trying to find out if this is a reliable source
linda
linda
linda_
3 yrs ago
7
replies
176
Last reply
Jay Orman
1 yr ago
Self-Experimentation
Do doctors prescribe rapamycin to people in their 20s?
I'm looking to experiment with Rapamycin. Does anyone have experience with getting it in their 20s?
rapalogical
rapalogical
3 yrs ago
9
replies
303
Last reply
Arizona Kid
2 yrs ago
Self-Experimentation
Has anyone tried urolithin A?
Urolithin A is a bacterial metabolite that enhances mitophagy, which declines as we age and allows dysfunctional mitochondria to accumulate. I just wanted to see if anyone has experimented with…
Will Hunter
Will_Hunter
3 yrs ago
31
replies
1568
2
Last reply
Karl
1 yr ago
Self-Experimentation
Red Blood Cells Decline During Aging, But Can Be Increased Through Diet
https://www.youtube.com/watch?v=3JpyDiNxNeE&feature=youtu.be
michael lustgarten
michael_lustgarten
3 yrs ago
5
replies
155
Last reply
Michael
2 yrs ago
Self-Experimentation
Kidney Function Declines During Aging-Can It Be Reversed?
In the video: Data for changes in kidney function during aging, kidney function values that are associated with an increased risk of death for all causes What's my data for kidney function,…
michael lustgarten
michael_lustgarten
3 yrs ago
10
replies
304
Last reply
Edward Meininger
3 yrs ago
Self-Experimentation
Who Else taking Acarbose for longevity?
I started taking Acarbose about 6 months ago after reading the ITP studies that showed a that it and rapamycin are the only two drugs approved for human use that have been shown to significantly…
Brin Chikovski
Brin_Chikovski
updated
3 yrs ago
3
replies
429
Last reply
Alex K. Chen
1 yr ago
Self-Experimentation
Micro-Dosing Lithium for Life Extension - How to Divide 300mg Tablet?
I've been reading the research on how low-dose lithium looks to be helpful in age mitigation as outlined in links below. I want to try it at the level of 5mg to 10mg a day.…
Brin Chikovski
Brin_Chikovski
updated
3 yrs ago
28
replies
431
1
Last reply
aribadabar
3 yrs ago
Self-Experimentation
Quantifying Biological Age With Aging.ai: 24 Blood Tests Since 2009
The maximal reduction for biological age when using the biological age calculator, Phenotypic Age, is ~20 years. In other words, if I'm 80 years old and my biomarkers are all reflective of youth,…
michael lustgarten
michael_lustgarten
3 yrs ago
57
Self-Experimentation
Epithalon
Anyone inject Epithalon? 1) Any suggestions on both reformulating 50mg Epithalon and daily dose? 2) Anyone have experience mixing in a facial cream? (ALA Mark's rapamycin cream as found all over…
Michael
Michael.1
3 yrs ago
5
replies
174
Last reply
Michael
3 yrs ago
Self-Experimentation
Quantifying Biological Age: Blood Test #6 in 2020
Discussed in the video: What's my biological age on blood test #6 in 2020? What's my average biological age for 2020, and how does it compare with 2019? Are there links between calorie intake,…
michael lustgarten
michael_lustgarten
3 yrs ago
38
Self-Experimentation
sirolimus vehicle
Does anyone have any sources for formulating aqueous solutions of rapamycin? I got my hands on 10g pure powder, and I would like to start the 5mg/week regimen.…
Anna Marie
Anna_Marie
3 yrs ago
6
replies
252
Last reply
Van
3 yrs ago
Self-Experimentation
Rapamycin and Blood Pressure Pills
Is anyone here taking Rapamycin along with high blood-pressure pills (Ace Inhibitors and amLODIPine)? I’m curious, as I’ve been doing a lot of research and the combo doesn’t seem all that positive.…
Paula Marie
Paula_Marie
3 yrs ago
3
replies
133
1
Last reply
Paula Marie
3 yrs ago
Self-Experimentation
Dogs and cats and people
I am learning something new every day. https://www.purinainstitute.com/can-summit/can-2018/new-insights-into-getting-older This has helped me understand what I read here better.
Jennifer Smith
We are all responsible for our own health, wealth, and happiness
Jennifer_Smith
3 yrs ago
68
Self-Experimentation
Biohackers Perform First Plasma Dilution Experiment on Humans This technique is a human modification of the Conboys' mouse experiments.
https://www.lifespan.io/news/biohackers-perform-first-plasma-dilution-experiment-on-humans/
Larry
Larry.1
3 yrs ago
8
replies
242
Last reply
Spasov
2 yrs ago
Self-Experimentation
Paul's self experiment II
My original thread was hi-jacked so starting another Still taking rapamycin. Experimented with GDF11 and will take blood tests in Jan to see if it has had an effect Looking into peptides.…
Paul Beauchemin
Paul_Beauchemin
3 yrs ago
2
replies
294
1
Last reply
Jay Orman
10 mths ago
Self-Experimentation
High dose nicotinic acid with acetyl-carnitine restores hair color?
I found out that high dose nicotinic acid (3+ grams) with high dose acetyl-carnitine (1+ grams) seems to be able to at least partially restore hair color in my father in his 70s,…
Big Guy
Big_Guy
3 yrs ago
5
replies
451
1
Last reply
Ludovic Debels
3 yrs ago
Self-Experimentation
Cosmetic Peptides
Anyone have experience with any of the (cosmetic) peptides on this site or equivalent? Tried the rapa cream formula suggested on the forum here with zero benefit.…
Michael
Michael.1
3 yrs ago
3
replies
208
1
Last reply
Rick Tolk
1 yr ago
Self-Experimentation
Neutrophils, Lymphocytes, Monocytes: What’s Optimal For Health And Longevity?
For those who track their WBC differentials, here's my latest video about what's optimal for neutrophils, lymphocytes, and monocytes in terms of health and longevity: https://www.youtube.…
michael lustgarten
michael_lustgarten
updated
3 yrs ago
52
1
Self-Experimentation
HDL: What's Optimal For Minimizing Disease Risk And Maximizing Longevity?
Meta-analysis for the association between HDL with all-cause mortality risk has identified HDL levels 55 - 60 mg/dL range as optimal. However, that data includes subjects up to 85y-in the video,…
michael lustgarten
michael_lustgarten
3 yrs ago
59
2
Self-Experimentation
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