-
Rapamycin in Nz or Australia
Hi guys First Post here, does anybody out there no of any doctors in either new zealand or Australia that will prescribe rapamycin? I've been trying but not having any luck sofar any leads would be…
-
Introduction to GDF-11
Hello everyone! I wanted to get the discussion about GDF-11 started with an intro and other basic information. GDF-11 stands for "growth/differentiation factor 11".…
-
Best bio markers
After months of research, I've come to the conclusion that there are two indispensable biomarkers everyone should track: HOMA-IR - Homeostatic Model Assessment - Insulin Resistance.…
-
hair growth tips
5 top UK barbers give their top tips for growing your hair out. Are you growing your hair out? Is your hair in that awkward growth stage? Barbers all noted below! https://shrinkme.io/hairgrow
-
Nicotinamide and Sirt1
It is the general belief that nicotinamide inhibits sirt1. However the authors of this paper argue that while NAM is a sirt1 inhibitor at larger concentrations. At 5mM it is an activator.…
-
I finally got rid of hyperpigmentation after years of trying many creams
Hi! I’m 39 and struggled with hyperpigmentation for few years because of the sun damage. With these three steps I got rid of it and I have no more stains on my face. https://youtu.be/qAwgIu2HKMo
-
Long term damage of non hospitalized positive COVID-19.
What kind of long term damage a non hospitalized positive COVID-19 person could endure, what tests would be needed to assess this issue?
-
Clinical trials locations
Suppose there's an anti aging clinical trial going on in the US, is it possible to participate in the same trial, but in another country, out of the US? I mean,…
-
Whole genome sequencing for $700-750?
Friends, I'm going to try to negotiate a deal with one of the companies offering whole genome sequencing to get the price down well below $1000. How many of you would be willing to pay around…
-
Levels of senescent cells correlates with death?
Interesting study https://www.nature.com/articles/s41467-019-13192-4
-
Just got my dasatinib capsules
I live in S.CA and went to Las Vegas to Dr Garcia who prescribed the dasatinib dosage promoted by Faloon. A few months passed while COVID-19 disrupted supply chains.…
-
Paul's Anti-Aging Efforts
Preparing for a LONG FUTURE, here are the prescriptions and supplements I take to STOP or REVERSE AGING, with the blessings of my doctors. After each one are the number of Web sites mentioning them,…
-
Vitamin C and the Corona Virus
I understand that IV Vit C has been used successfully in many cases to cure deadly infections, e.g. sepsis and Corona. Here is a link to one source. https://www.youtube.…
-
"Insufficient" dosage leads to "no effect" or "small effect"?
My assumption is that scientific researchers need to "show immediate results" and that is why they use such, in some cases, massive dosages. We, on the other hand,…
-
Rapamycin in Mexico
I live close to the California/ Mexico border. Does anyone know if Mexican pharmacies sell rapamycin?
-
32 years old. Is self-experimentation right for me?
So, as the title says, I'm 32 years old. I'm very interested in longevity research and I would like to try some of these methods to help slow my aging.…
-
Senolytic Self-experiments and COVID-19
There is evidence that the TOP2 receptor that the COVID-19 virus uses to enter cells is more prevalent in senescent cells. Also, clearing accumulated senescent cells from the immune system probably…
-
Life is an experiment
I've been working on "me" for years and lately I've started to look beyond diet, exercise, lifestyle, sleep etc. Until now I've only been supplementing with creatine, fish oil,…
-
Did anyone experience acute inflammation after senolytics?
Hello, I have Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. It is a condition that involves chronic inflammation. I tried 3 days of high dose Fisetin the last 3 days (1000mg/day).…
-
Power a Longer Life via NAD+ Restoration
A coenzyme called NAD+ supports DNA repair and other youthful processes. Restoring NAD+may halt certain degenerative factors, boost brain function, and reduce risk for age-related disorders.
-
Trehalose
Has anybody researched or tried trehalose to kill senescent cells? I have just come across it in the literature, apparently it stimulates AMPK like Metformin does,…
-
Restore NAD+ Level without NR or NMN
To keep NAD+ levels high, almost everywhere I look, it is suggested that we must supply precursors (NR or NMN), so that we can induce "production" of NAD+. Both NR & NMN are not cheap.…
-
Add a category for local meetups
I have a local life-extension focused meetup I'd be glad to announce, and I'm sure others would like to connect in their areas as well. Would you consider adding a Local Meetup category?