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Rapamycin, etc. at 3pm EST today Q&A: Dr. Richard Miller
Richard Miller will be answering questions today. One of the questions posed involved a vignette re: a patient taking 20 mg of rapamycin every week ( doing well).…
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Quantifying Biological Age: Blood Test #4 in 2021
https://www.youtube.com/watch?v=ue-mzz1bm3E
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Selenium: How Much Is Optimal For Health?
For those who track their diet, eating only the RDA for many nutrients may not optimize health. For example, the RDA for selenium is 55 micrograms per day,…
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Lifespan, Cold-inducible RNA-Binding Protein (CIRBP), and Bowhead Whales
This morning at ARDD2021, Prof. Vera Gorbunova (U. Rochester) gave a paradigm-shifting talk about the mechanism behind maximum lifespan. The human maximum lifespan is about 120 years.…
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Young and Undamaged rMSA Improves the Healthspan and Lifespan of Mice
https://www.youtube.com/watch?v=GlFkid9cY_4
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Age Reversal Startup-Altos Labs
https://www.dailymail.co.uk/news/article-9960175/Jeff-Bezos-Yuri-Milner-fund-anti-aging-start-up.html
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A different point of view
Interesting article that argues for telomere therapy and against senolytics. https://www.leafscience.org/are-senolytics-potentially-damaging-for-longevity/
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Quantifying Biological Age: Blood Test #3 in 2021
https://www.youtube.com/watch?v=hvKogCUOqyA
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Breakdown of epigenetic aging tests you can buy now + Sinclair's upcoming test?
Been following this thread and thought I'd breakdown two tests often mentioned here: the Index test and MyDNAge. https://healthandwealth.substack.com/p/epigenetic-age-testing I also talk about the…
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My Journey To Reduce My Epigenetic Age
I am using mydnage.com and paying top dollar to get the most accurate Horvath based test. Here are my results. Not sure how reliable these numbers are since they could still be within the margin of…
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Which Gut Bacteria Are Associated With Poor Health, And How Can We Limit Them?
https://www.youtube.com/watch?v=uraF-eD4xgY Papers referenced in the video: Human microbiome: an academic update on human body site specific surveillance and its possible role https://pubmed.ncbi.…
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The Pace of Bio-Aging from DNA Methylation
At the recent 2021 Conference on Ending Age-Related Disease, Prof. Daniel Belsky (Columbia U) gave a talk on his work in using DNA methylation information to determine how fast a targeted tissue is…
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Homocysteine Increases During Aging, But Can Be Reduced With Diet And Targeted Supplementation
https://www.youtube.com/watch?v=y6joAp_UghQ&t=1s Papers referenced in the video: Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway: https://pubmed.ncbi.nlm.…
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FDA not allowing drugs in?
I got a disturbing letter from the FDA two weeks ago. I had ordered some cialis and letter indicated importing drugs already approved was illegal and shipment was destroyed.…
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Scenescent fibroblasts
Hi - first post/new here. I've read with great interest about senolytics and I'm specifically looking for something that could target fibroblasts. I'd found extract of milk thistle flowers that is…
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Interested in Self-experimentation Protocol
Hi Everyone, I'm new to this forum and would like to ask some questions. I apologise if these questions have been asked before, I did a search through the forum but could not find the answers.…
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Dietary CD38 Inhibitors: Are They Correlated With Biological Age?
https://www.youtube.com/watch?v=ESCIfQp7z-U
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Is there still any reason to bank your own stem cells when Brent Nally can use stem cells from someone else in mexico?
https://twitter.com/brentnally/status/1187588132591398912
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New Slides From Bill Faloon
Have you noticed that Bill Faloon has posted hundreds of new slides? These are from a conference that he presented to very recently. Definitely worth viewing.
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How to increase the bioavailability of Fisetin
I'm preparing to do a Fisetin senolytic experiment, but I've read on the article from Mayo Clinic ( https://linkinghub.elsevier.com/retrieve/pii/S2352396418303736 ) that the administration mode was…
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The problem with this forum and others as I see it
I love it and truly appreciate the intelligent back and forth BUT, physical photo-aging evidence is entirely lacking. PHOTOS. I don't care about your blood sugar levels.…
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Cycling Rapamycin with NAD+ Precursors
I have been taking the NAD+ precursor NMN (250mg daily, sublingually) for the past several months and have recently added Rapamycin (5mg weekly). I was wondering whether it would be a good idea to…
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Epigenetic Age Reduction Within 8 Weeks: Real Effect Or Statistical Noise?
https://www.youtube.com/watch?v=bwOjSnCYGCM
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My story (your suggestions) Dr Arvind Poswal
Hi. I am new here. Would like to know your thoughts. I begin by detailing my major life health points. I think I am a good candidate for knowing the effects of many of the anti-ageing medicines.…