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Trametinib - is it still just theoretical?
Hi Everyone, I just watched Bill Faloon at RAADfest 2023 (https://www.youtube.com/watch?v=nfaZ_0Rajdc) and saw he mentioned trametinib. Is it still theoretical at this point or have studies been…
- ROB KRAFT
- ROB_KRAFT
- 1 yr ago
- 22
- Senolytics Discussion
Sources for inexpensive prescription Rapamycin
My understanding is that in the U.S. Rapamycin is expensive with prescription, but it can be purchased overseas for much cheaper. Recommendations for pharmacies (compounding or otherwise) that have…
- Danmoderator
- skipping my funeral
- dantheman
- 6 yrs ago
- 169replies
- 6178
- 3
- Last replyKeith lankheet1 yr ago
- Rapamycin Discussion
Blood Test #6 in 2023: 17 - 23y Younger Biological Age
https://youtu.be/RYqDPi3TzqI
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 1reply
- 28
- Last replymichael lustgarten1 yr ago
- Assessing Biological Age
Senolytic Effects of FOXO4-DRI
I found this research on target specific effects of FOXO4-DRI to be interesting. Please add your thoughts and links to any other research. Could this be a viable experimental therapy? https://www.…
- Dorian Gray
- Dorian_gray
- 5 yrs ago
- 12replies
- 590
- Last replyJohn Mcgough1 yr ago
- Senolytics Discussion
Recent Plasma-Replacement Results
Two recent results have been published that are worth reporting here and are recommended for careful reading. The first of these is a paper by Dr. Harold Katcher, Dr.…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- 113replies
- 1544
- 2
- Last replydale koester1 yr ago
- Young Plasma Infusions
My anti-aging journey - How long for the collagen?
Family and I will be addressing the 9 hallmarks of aging, including genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, deregulated nutrient-sensing,…
- Luke Duran
- Luke_Duran
- 1 yr ago
- 4replies
- 157
- 1
- Last replyLuke Duran1 yr ago
- Self-Experimentation
Acylcarnitines Increase During Aging, And Are Associated With Poor Health
https://www.youtube.com/watch?v=IZwByAQrt_Q
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 28
- General Discussion
Bill Faloon's Petition
We have been LEF supporters and wholesalers for decades, and are also ARN physician providers. Astonished to hear in Bill's excellent presentation at RAADFest last night about the petition he had…
- Louise B Andrew
- Louise_B_Andrew
- 1 yr ago
- 1reply
- 42
- 1
- Last replyGary1 yr ago
- General Discussion
Higher HRV, Lower RHR: Potential Impacts For Weight Loss And Consistent Exercise Training
https://www.youtube.com/watch?v=1bNF-i0-ALo
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 19
- General Discussion
Resting Heart Rate, Heart Rate Variability: What's Optimal, 1,877 Days of Data
https://youtu.be/hFgQT_BzGKI
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 18
- General Discussion
NUCHIDO
Has anyone tried the NAD booster Nuchido? They had products for sale at RAADfest and went live with online sales recently.
- Mel
- Mel
- 5 yrs ago
- 49replies
- 3224
- 2
- Last replyDavid Young1 yr ago
- NAD+ Restoration
Cholesterol Esters: Underrated Metabolites That Are Associated With Youth And Survival
https://www.youtube.com/watch?v=KhKYKvpKfJ4
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 30
- Self-Experimentation
Astaxanthin - A proven life extending supplement?
New and unpublished data from the ITP (Interventions Testing Program) show that Astaxanthin is one of few substances that show life extending effects, At least when tested rigorously in the programs…
- Staffan Olsson
- Staffan_Olsson
- 3 yrs ago
- 5replies
- 618
- 1
- Last replyMoonlitnight1 yr ago
- Self-Experimentation
NAD+ Concentration conversion
One maker of a NAD+ booster is claiming their trial was a success based on seeing a 17 ng/ml increase in intracellular NAD+. But they did not provide baseline or control NAD+ levels.…
- Peter
- Peter.2
- updated 1 yr ago
- 54
- 1
- NAD+ Restoration
Fish Oil Supplementation: No Impact On NAD
https://www.youtube.com/watch?v=AkAoLO4eBFY
- michael lustgarten
- michael_lustgarten
- updated 1 yr ago
- 22
- General Discussion
Did Niacin (Or NAD Being Too High) Mess Up The Epigenetic Pace Of Aging?
https://www.youtube.com/watch?v=E1vV_iu41fk
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 47
- Self-Experimentation
Albumin, CRP, and Creatinine: Better Markers Of Longevity Than Lipoproteins And Glycemic Status
https://www.youtube.com/watch?v=LOdR6KkRBgQ
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 25
- 1
- General Discussion
Supplemental Tryptophan: Impact on NAD?
https://www.youtube.com/watch?v=8FcnNfRo--w
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 29
- Self-Experimentation
Qualia Senolytic product
Having booked a lot of success with improving my NAD+ levels by taking resveratrol and a NAD precursor ( which I've described in another forum ) I decided to take the next logical step and tackle…
- David Young
- David_Young
- 1 yr ago
- 9replies
- 107
- 1
- Last replyBrian Valerie1 yr ago
- Senolytics Discussion
Calorie Restriction, Exercise, And Longevity: Luigi Fontana, MD PhD
https://www.youtube.com/watch?v=yHFxYjTeMPY
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 22
- General Discussion
Easy way to support the Human Age Reversal Project
Hello everyone, The primary non-profit organization we use to support human age-reversal projects is the Human Age Reversal Project. You can donate here on our website.…
- Maximus Peto
- Researcher, website & forum admin
- Maximus
- 5 yrs ago
- 2replies
- 203
- 2
- Last replyLouise B Andrew1 yr ago
- Announcements
Impact Of Microbes On Aging And Age-Related Disease
https://youtu.be/983YZ02BUuI?t=1s
- michael lustgarten
- michael_lustgarten
- updated 1 yr ago
- 14
- General Discussion
I've Got A Big Problem In My Oral Microbiome (Serratia marcescens), But Also A Plan To Reduce It
https://www.youtube.com/watch?v=KrgCNvqyoqY
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 20
- General Discussion
Did Tryptophan And/Or Serine Mess Up Blood Biomarkers? (Blood Test #5 in 2023 Analysis)
https://www.youtube.com/watch?v=GQXd-iimf1A
- michael lustgarten
- michael_lustgarten
- 1 yr ago
- 16
- Self-Experimentation
Increase NAD With Fish Oil (And Other PUFA-Containing) Fatty Acids? Hypothesis.
https://www.youtube.com/watch?v=fXEDlFZbvkE
- michael lustgarten
- michael_lustgarten
- 2 yrs ago
- 2replies
- 30
- Last replymichael lustgarten1 yr ago
- General Discussion

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