Sources for inexpensive prescription Rapamycin

My understanding is that in the U.S. Rapamycin is expensive with prescription, but it can be purchased overseas for much cheaper. Recommendations for pharmacies (compounding or otherwise) that have websites where it can be purchased if you have a prescription? Canada would be ideal. 

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  • Look to the website 'goodrx' to get a coupon redeemable at most us pharmacies where prescription rapamycin is about only $160 for 30 1 Mg Sirolumis pills.

    Reply Like 1
    • are we there yet   Where did you receive an rx from for Sirolumis/ Thanks.

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    • sandi thompson ....I use a local dermatology doctor in houston that is forward thinking and familiar with Alan’s greed website.

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    • are we there yet are we there yet Thank you for your kind reply.  HOw did you go about finding the "forward thinking" dermatoligistin this sea of looking.  Thank you

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    • sandi thompson 

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    • I currently take 4 mgs of Rapamycin once per week.  Prescription that I fill at my local Walmart using the Goodrx codes.  Cost is $137 for 30 tablets at 1 mg.

       

      I also take intermittent Dasatinib, Quercetin and Fisetin and plan on adding FOXO4-DRI next year

      Reply Like
      • angie4life
      • angie4life
      • 7 days ago
      • Reported - view

      Charles Grashow , where do you obtain your dasatinib, and what dosage do you take, if you don't mind me asking.  Thanks so much!

      Reply Like
      • garland
      • garland
      • 6 days ago
      • Reported - view

      Charles Grashow Where do you plan on Getting FOXO4-DRI? And from what I read it needs to be injected and tested before one uses it to make sure it does not have any toxic substances.... since it primarily comes from China it is very scary.....

      Reply Like
  • Go to Pharmacychecker.com They have a number of certifications and checks in place, so you are more likely to find a reputable overseas pharmacy using them. However, be aware that "Canadian" pharmacies (or pharmacies with "Canada" in their name are not all Canadian. And many that are located in Canada source their materials from other countries.

    Reply Like 2
    • Louise B Andrew .... interesting link for foreign pricing of Sirolimus, but only a slight saving from GoodRx US based prescription pharmacy. I’ll stay US.

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    • Louise B Andrew Rapamycin not listed on there/

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    • Louise B Andrew Thank you for your kind reply.  I'm familiar with the pharmchecker, and will utilize it once I can find a local dr that will ok me for this rx. I'm not sure it's good to just give it a go without some blood tests from a like minded dr. 

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  • Reply Like
      • Van
      • Van
      • 9 mths ago
      • Reported - view

      Van 

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  • I have used this company for 2 years, with multiple shipments.. Bicon brand Sirolimus excellent.. $1.75 mg when buying 200 or more. Have other drugs also, Metformin, etc.

    Reply Like 1
    • Van Thank you!

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  • www.antiaging.clinic has 12x 5mg tablets (Rapa-Pro) for $89.99 and donates 15% to research. Entry code is 'Research'

    Reply Like 1
      • HB
      • raspberry_skate
      • 8 mths ago
      • Reported - view

      IAS Phil 

      They are asking for a referral code. How can I get one?

      Thanks

      Reply Like
      • IAS Phil
      • IAS_Phil
      • 8 mths ago
      • Reported - view

      HB hello- the one associated with this group is: research 

      Reply Like
      • razorray
      • razorray
      • 7 mths ago
      • 1
      • Reported - view

      IAS Phil 

      Reply Like 1
    • IAS Phil www.antiaging.clinic states that you have to order 6 units at once.   6 x89?

      Reply Like
      • IAS Phil
      • IAS_Phil
      • 6 mths ago
      • 1
      • Reported - view

      sandi thompson Not at all! You may order one box if you like. The maximum order is six units at a time, it is done to comply with the FDA personal importation limits. No one understands these procedures better than IAS because no one has been doing it longer than us (27 years now).

      Reply Like 1
    • IAS Phil Thank you anda good company to utilize.

      Reply Like
      • IAS Phil
      • IAS_Phil
      • 2 mths ago
      • Reported - view

      sandi thompson no the maximum purchase is 6 units per order 1 can be purchased 

      Reply Like
    • @IAS Phil  I had been taking 1mg per day of real rapamycin for an autoimmune condition. My blood levels were slightly low at 2.2ng at a dose of 1 mg per day. I purchased rapamycin from the antiaging store (after confirming with them that it was in fact rapamycin), at an increased dose of 1.5 g per day. My levels are now lower than the assay can detect. Clearly the product is NOT rapamycin. I am furious. My advice is that you should NOT purchase from this company.

      Reply Like
      • IAS Phil
      • IAS_Phil
      • 1 mth ago
      • Reported - view

      Steve Roedde I can assure you that the Rapa-Pro contains Rapamycin, it is formulated by an EU licensed compounding pharmacy and independently assayed by a lab. Brian Delaney has seen the certification with his own eyes. 

      Reply Like
      • IAS Phil
      • IAS_Phil
      • 1 mth ago
      • Reported - view

      Steve Roedde I am also confused as to how you obtained a dose of 1.5 mg of Rapa-Pro. If you are using one quarter of the 5 mg tablet it would be 1.25 mg - is this what you mean?

      Reply Like
      • Van
      • Van
      • 1 mth ago
      • Reported - view

      IAS Phil    Why don't you post the lab assay of your Rapamycin here on this forum.  Will go a long way with your credibility.

      Reply Like
      • IAS Phil
      • IAS_Phil
      • 1 mth ago
      • Reported - view

      Van it is a fair question Van, but the answer lies in the complex arrangement of contracts that are between the raw material producer, the compounder and the distributor. Accordingly, in a similar way that Pfizer doesn't release stats on Viagra, since it tends to only be ‘Mom and Pop’ organisations who choose to ignore any contractual or privacy agreements they may be obliged by.

      Therefore,, we retain the certificates and only release them to organisations under an NDA. 

      Somewhere on the forum I have stated before that Brian Delaney of the Age Reversal Network has already done so and seen them. He has a post on this forum saying all was satisfactory.

      Reply Like
      • Ozone8
      • Ozone8
      • 1 mth ago
      • Reported - view

      IAS Phil Kind of a moot point now since the RapaPro is not even in stock. I sent them a messaging requesting info on when it might be available but received no answer.

      Reply Like
      • IAS Phil
      • IAS_Phil
      • 1 mth ago
      • Reported - view

      Ozone8 please tell me when you sent your email and what site or email you sent it to and I’ll chase it down.

      Reply Like
      • Ozone8
      • Ozone8
      • 1 mth ago
      • Reported - view

      IAS Phil I used the online contact form so don't know the email address that might have gone to. And sorry but I don't remember exactly when it was sent but was in the past several days. Thank you.

      Reply Like
    • IAS Phil I take 1.25 mg then cut 1.25 into 5with a pill cutter. Given the prolonged half life of real Rapamycin the varied thickness should not matter and should even out. Unlike other forum users, I take it daily... and was trying to get to 4ng levels... (low renal-transplant levels). I can’t recall if I posted screenshots of my levels (I’m in my phone at the moment and site navigation difficult), but can do so if people have concerns. As I said, I will have more info next week when I see what 2.5 times the 1mg dose I was stable on does. 

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    • Van 

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  • self experimenting sirolimus note from me. sirolimus reduced arthritus, and improved heart circulation, but at 4 mg dose I got a severe chest rash or hives 2 days after a dose. It fully cleared up after 14 days on a steroid. I will restart soon on a lower dose and be vigilant.

    Reply Like 1
    • are we there yet My rash occurred on both feet in October /18. Has not fully disappeared as of today. I have stopped and started 4mg week Sirolimus twice in that time with no effect on the rash. Onward trough the fog.

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    • Patient 139 ..........through the fog.

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  • In reply "to are we there yet", I have been taking 6 mg rapa  once weekly for 2 years with zero side effects.  I am 72 yo, and feel that it is a waste of money to take rapa before the age of 60.  Tor signal still quite low before that age.  A good read is 

    https://rapamycintherapy.com/

    On another topic:  Has anyone ordered rapa from the antiageing clinic above.  If so, how is the service and who is manufacture of rapa.

    Reply Like 2
  • I am very interested in using Rapamycin. After reading a numbers of papers on the subject of Rapamycin and its possible anti-aging actions. 

    I have looked around at the many online suppliers and see the pricing is just too high, as are the commercially available tablets.

    I am currently having 5mg capsules compounded by a compounding pharmacy for me at a much lower pricing but the only draw back is the large amount of capsules I needed to order.

    Reply Like
      • IAS Phil
      • IAS_Phil
      • 4 mths ago
      • Reported - view

      Darren This forum is supported by IAS who donate 15% of all such orders to the research.

      Rapamycin. (Rapa-Pro) is offered at 12x 5mg at $89.99 note that the tablets are scored so can be broken.

      The site set up for this forum is: www.antiaging.clinic and the passcode is: research 

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    • IAS Phil , might you know when IAS will have the RapaPro back in stock?   My pup and myself have been happily using it, but alas, its been out of stock for a while, as has the low dose naltrexone (NalPro), another great product.

      thanks so much!

      Reply Like
      • IAS Phil
      • IAS_Phil
      • 1 mth ago
      • Reported - view

      angie4life I’ve asked Marc to reply- he is our buyer and in charge of stock operations. I’m pretty sure both are expected soon.. 

      Reply Like
  • I am looking to obtain 1 mg tablets or capsules of rapamycin/sirolimus to be given to a small, 15 lb. dog.

    If anyone has a quantity of 1 mg tabs they might want to provide (with appropriate compensation of course), please respond.

    Am also interested in a joint buy, perhaps with dropshipmd or equivalent.

    The antiaging.clinic option would be great if they offered 1 mg. The 5 mg size is too large to divide accurately. Thank you.

    Reply Like
      • Darren
      • Darren
      • 4 mths ago
      • Reported - view

      Ozone8 I want to support the forum sponsor but if they don't have what your after I have some experience in getting capsules compounded so if you are still interested PM maybe I can help.

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      • CSC
      • CSC
      • 2 mths ago
      • Reported - view

      Darren 

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      • IAS Phil
      • IAS_Phil
      • 2 mths ago
      • Reported - view

      Ozone8 the 5mg tablets are double scored which means they can be broken twice so either 2.5mg or 1.25mg 

      Reply Like
    • IAS Phil but that’s just the dose on the label. There is no Rapamycin in the bloody pills!

      Reply Like
  • Thanks for that info, ias_phil.

    The dosage for my dog would be about .65 or 1/2 of the smallest scored division of the tablet. Do you think it would be possible to relatively accurately divide the 1/4 tablet in half?

    Reply Like
      • IAS Phil
      • IAS_Phil
      • 2 mths ago
      • Reported - view

      Ozone8 yes the tablets can be split again- but in such cases I’d recommend a proper tablet splitter, they are inexpensive as generally it is a blade inside a screw down tube.

      Reply Like
  • My experience with ias has been nothing but positive, and I've ordered from them for years.  The Profound products are of good quality, I believe, including the Rapamycin.  Only thing is , it's been out of stock for several weeks, and I'm hoping they will get some more in.  I also use their low dose naltrexone, also made by Profound, but its been out of stock or months now.

    Reply Like
    • angie4life my experience would have been “positive” too... had I not checked my levels.  At this point, I’d have to assume all of their drugs are fake. I could have ended up on a ventilator because of them!

      Reply Like
  • Hello Angie,

    We hope to have RapoPro back in stock during the first week of September and will keep you updated. NalPro will be a bit longer.

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    • CSC I hope to have an updated sirolimus (Rapamycin) level by September 5th or 6th. Hopefully this will clarify whether the dose is just low and misstated... or a fake drug. 

      Reply Like
  • Our apologies for the lack of stock but RapaPro should be available from https://antiaging.clinic w/c 9th September. (Login code is Research). Other products such as DasaPro (Dasatinib), Metformin, Oxytocin and Deprenyl in liquid and tablet form are also available from this site.

    In answer to an earlier question RapaPro is manufactured in Greece and is supplied in packs of 12 double scored 5mg tablets at $89.99 per pack. Below is the CofA for the new production. As mentioned before 15% of the goods value is donated to Age Reversal Research.

    Reply Like 1
    • CSC this shows that the silica in the pill is clean. Please provide proof it contains Rapamycin! My “RapaPro” contained NONE.

      Reply Like
      • Ozone8
      • Ozone8
      • 1 mth ago
      • 2
      • Reported - view

      CSC So what are we missing? This CoA appears to only address lack of any contaminants in the "white powder". Where is the verification that it is actually rapamycin? I have an order pending with AntiAging.clinic  but need to be confident that I will be getting more than white powder. Comments  please from IAS Phil and CSC?

      Reply Like 2
    • CSC can you please provide an explanation for the data reported in this COA?  

      Going by the title "certificate of analysis", the supplied document should be stating the contents of the drug being analyzed.  

      Yet, we do not see Sirolimus or Rapamycin anywhere in the report, simply the names of some possible bacterial contaminants.  

      Also, there are two fonts on the report, and some unusual spacing (between Identification and Optical), and also some misspellings.  

      This does not inspire confidence.  

      I am a physician, and a long time customer of IAS/AAS.  

      I would appreciate more reassurance, especially in view of the experience of others on this forum, reportedly with this product.  

      What is the T 1/2 of Rapamycin?  Is the fact that the level of the member who is disappointed was drawn >24 hrs after the last dose helpful in terms of analyzing the reported lab result?  

      Thank you.  

      Reply Like 1
  • As promised, I have an update on my RapaPro from AAS. I took 2.5 mg of RapaPro for 12 days. My repeat Ramamycin shows that there is no Rapamycin at all in the pill I received. I asked for a full refund, and I received a nice reply from the company saying they would send one. I will report back when it arrives. Sadly, because I took a fake drug, my potentially life-threatening autoimmune conditions have been untreated for two months. The only advice I can offer after my experience is that you must have A mechanism to prove you are getting what you have been sold. In my case, my life was in jeapordy because of this. It might not just be money you are wasting! 😰 

    Reply Like
  • Well, that is certainly disappointing.

    I have just placed an order though not funded it yet. I was hoping to use their echeck payment method but can't figure out how to do it. I am not willing to send sensitive banking information in an unsecured email format. But if the product is not really rapamycin....

    Steve, what was your sirolimus level when tested after using a more "legitimate" source?

    Reply Like
    • Ozone8 2.1 and 2.2 at 1 mg per day. Sadly, $12 per day for real Rapamycin. I looked into Dropshipmd... it looks potentially sketchy too. 

      Reply Like
      • Ozone8
      • Ozone8
      • 1 mth ago
      • Reported - view

      Steve Roedde That is really too bad. I, too, contacted Dropshipmd at one point. I did not get the same feeling that they are sketchy but did not follow through with an order. I have seen other posters who have ordered from them successfully. And the brand they sell, Biocon, is a well known Indian pharmaceutical company. The price quoted was $1.75US for 1 mg tablets.

      Reply Like
    • Ozone8 I had nearly purchased from them... but the wire payment was to somewhere else... Taiwan or Hong Kong... can’t recall exactly. It made me nervous. AAS had a nice website and I was suckered. I found this thread for Dropshipmd... scroll down till you get to the bit about their “office”. I don’t trust anyone anymore. Sadly, my chance at actually receiving a refund is probably zero now... but I felt compelled to share... 


      https://pharmacyreviewer.co/forum/pharmacies-not-yet-featured-in-the-reviews-section/53680-anyone-heard-dropshipmd.html

      Reply Like
    • Ozone8 “Other sellers weren’t always what they appeared to be. DropShipMD, a “distribution, trading and drop shipping” company, says on its website it will ship generic Sovaldi made by Mylan for $1,300 and other generic versions for $1,500 to customers in the US and Europe with a prescription via express mail. It also offers patients the option to pick the drug up in Mumbai with cash.

      Located at the address listed for DropShipMD, a basement unit in a rundown Mumbai apartment, is another pharmaceutical exporter, Vivin International. Ramesh Akkela, CEO of Vivin International, said his firm has no affiliation with DropShipMD, which he said was using his address without his permission. Akkela said his company does sell Natco’s generic Sovaldi to Singapore and Africa, though he insisted it doesn’t ship to the US.

      “When the margin is that high, there are going to be a lot of people who will try to make a quick buck on it,” said Agrawal.”

      Reply Like
      • Ozone8
      • Ozone8
      • 1 mth ago
      • Reported - view

      Steve Roedde That doesn't sound good. I did not do much research on DropShipMD and now will likely not bother with them.

      BTW, the wiring instructions I received from AAS list HSBC bank in Hong Kong.

      I obtained some "rapamycin" from:

      https://teamtlr.com/anti-aginglongevity-research/169-rapamycin-cas-no-53123-88-9.html?search_query=rapamycin&results=1

      They provide a powder that must be divided and put in capsules. I have no proof that it was actually rapamycin but I did get one of the common side effects after taking. And using it for nine months or so produced some of the changes mentioned by Dr. Alan Green and others.

      Given your medical needs I am not recommending True Life Research (TLR), just mentioning my experience

      Reply Like
      • Van
      • Van
      • 1 mth ago
      • Reported - view

      Steve Roedde Steve Roedde I have ordered rapa from dropshipmd.com 6 times. The experience has always been very positive. They send me Bicon rapa. Did not try and make money on shipping. 3-4 weeks with regular shipping. I have nothing but good things to say about them. Been taking rapa for 3 years. 73 yo male The hassle is wiring the money. I asked them about credit cards, and they said the credit card companies charge 15% to process the card from India. That is why they don't offer it. They ship to the US in very good packaging and have never had a problem with customs. No Rx required. So all these reservations about dropshipmd are unfounded in my experience. They have been very ethical with me. Also, I ordered 500 and got a discount to $1.50 mg.

      Reply Like
    • Van I have no idea whether Dropshipmd md supplies real Rapamycin. It seems that some have also been happy taking the placebo I purchased as well. I do not have any particular concerns about payment mechanisms or the state of their office. Do you know for certain you are taking Rapamycin? Have you had a level checked? Even taken once per week as most of you folks would, a level taken the next day would likely show a “toxic” level because the normal values are designed for trough levels. 

      Reply Like
      • Van
      • Van
      • 1 mth ago
      • Reported - view

      Steve Roedde Are uou kidding.  Bicon has a AAA rating manufactures and ships $100 Billion of drugs around the world every year. They are much more reliable than this site.  I would have never ordered from here.  Check Dun and Bradstreet, Linkin.

      Reply Like
    • Van No need to be hostile. Are you certain your Rapamycin is made by the manufacturer stated? I have a Pinarello bike that hardly anyone can tell from the real deal... except its not. $780 for the frame instead of $8K. There are counterfeit bikes, counterfeit handbags ... and counterfeit drugs. How do you know? I was burned once. Now I'm more cautious. Has anyone purchased from dropshipMD and had their pills tested? Or a serum level done? That would go a long way to reassure me.

      Reply Like
      • Van
      • Van
      • 1 mth ago
      • Reported - view

      Steve Roedde There are aliens in Area 51 also.  All of the conspiracy theories are one thing for fly by night firms but established firms that is ridiculous.  I guess Pfizer or Novartis will be the next target.  Anything short of complete drug analysis is very suspect.  

      Reply Like
    • Van sarcasm is often amusing... but unsurprisingly you missed my point. I’ll try and be more clear for you... because you seem to have difficulty with nuance and simple concepts. I was not implying that the big pharma firms (either brand name or generic), were in the business of making fake drugs. I was suggesting that in many nations (China comes to mind), knock-off products are a winning business model. This applies to branded medications as much as handbags. So (and pay attention so as to not misunderstand again), it is conceivable that a drug with a particular “brand”, marking or insignia, stamped on the pill, may not in fact, be manufactured by the company identified. Again, because you seem to have difficulty comprehending a simple concept, I am providing an explanatory link. 


      https://en.wikipedia.org/wiki/Counterfeit_medications

      Reply Like
  • I have done more hard thinking about my experience with placebo sold as “RapaPro” purchased through the AAS. I implied that the store itself is complicit in the fraud. This is possible, but not certain. I know nothing of their supply-chains or who makes their products. Although they are ultimately responsible for selling mis-labelled placebo, it is possible that they have been victims, not perpetrators of this fraud. However, if this is the case, they should provide  clear, transparent and complete information about how things went so terribly wrong. Until then, I’d have to view any product sold by them with suspicion. As for other suppliers such as Dropshipmd, at the moment, I will go back to the grossly overpriced “Rappamune” and suck up the $12 per mg. I can sell some stuff. However, if anyone can offer evidence that any of these companies sell the real deal, I will be willing to take another risk.

    Reply Like
    • Steve Roedde the manufacturer of the RapaPro is Profound Products .  They make so many other anti-aging / health products , and have a website as well , although they don’t sell to the public .  I’ve purchased and used lots of their supplements , including RapaPro , MetPro(Metformin ), NalPro(low dose Naltrexone), and just  recently DasaPro ( Dasatinib).   They have always seemed a reputable company , as their products are carried at other places as well , so disappointed to hear about your experience !  You may wish to contact Profound Products  directly . I’ve emailed them before regarding product availability, and they responded promptly.

      Reply Like
    • angie4life , I'll leave it to the AAS to deal with their manufacturer. As I said, that the drug was fake is certain... How wide the fraud goes, and what drugs are involved... I do not know or care. I've done my bit to wann folks.

      Reply Like
      • Ozone8
      • Ozone8
      • 1 mth ago
      • 2
      • Reported - view

      angie4life To me it is disappointing that there has been no response here from the people involved with AAS. Steve posted his lab results and described his regimen of taking RapaPro. Something is going on there.

      And the COA that was kindly provided really does not indicate the existence or lack of rapamycin. It is of no value.

      I am still waiting to complete my RapaPro order.

      Reply Like 2
      • angie4life
      • angie4life
      • 1 mth ago
      • 1
      • Reported - view

      Ozone8 , I agree , and believe IAS should be concerned as well , as they carry other products from Profound as well .  I just ordered DasaPro (Dasatinib) , and do hope it’s the real deal .... the manufacturers’s website (PROFOUND PRODUCTS), looks very professional, and states they’ve been around since 2001 as wholesale distributors for innovative products of interest to “the Antiaging physician and the life extension enthusiast “.  I’ve ordered so many products manufactured from them in the past , and never had any suspicion they might be inert medications .... i sure hope not !

      Reply Like 1
    • ....a poor mans chemical analysis is to crush and taste a US sirolimus pill, and remember it’s taste (spit out if you wish), then taste the Indian sirolimus and see if the taste is different before you try an expensive lab spectro analysis.

      Reply Like 1
      • Ozone8
      • Ozone8
      • 1 mth ago
      • Reported - view

      are we there yet Given that mouth sores (stomatitis) are the most common side effect of rapamycin usage, I will not be doing the taste test you suggest.

      Reply Like
    • are we there yet The serum trough testing is widely available and probably not too expensive... no spectographic analysis required. If the rapamycin is prescribed by an MD... quite possibly covered by insurance as well...

      Reply Like
  • Using goodrx app I buy 500 mg tablets of metformin at 180 pills for under $18 or about 5 cents per pill all made in reliable America.  And get sirolimus using goodrx from Kroger at quantity 20 of 1mg for $100. Or about $5 per 1mg pill.

    i have faith in US pharmacies for quality more than foreign sources. However, dasatinib is so costly I would consider the risk of a foreign source.

    Reply Like 1
      • garland
      • garland
      • 1 mth ago
      • Reported - view

      are we there yet  Yes I did the same thing.... and got mine through Walmart pharmacy and am paying about 4 dollars and 30 cents a tab using the same Goodrx coupon. I bought 120 at a time though. However since a new study came out that Sirolimus suppresses NAD I have been hesitant to use it. Also I travel alot and am exposed to more germs since I am around lots of people so I have been hesitant to do that as well....Dr Green says that it gives one vulnerability to regular germs.... not sure what to do with this...

      Reply Like
    • garland ... I agree..I adapt and have been happy with 2 to 3 milligrams per 7 day cycle. Less than half of Dr. greens protocol. And if I am going on a airplane, or get a flue shot, I skip a weekly dose cycle before it. Sirolimus does make one feel younger. Espicially if you had stiff or sore joints. Very anti inflamitory. I also take NAD supliments but have noticed little from them.

      Reply Like 2
      • garland
      • garland
      • 1 mth ago
      • Reported - view

      are we there yet   Thanks for your ideas... I like them and will try to implement them.. I did talk briefly with Dr Green and he suggested a smaller dose as well. I just read a study done on NAD which compared injections with oral use and found that the NAD only really got to the organs with the injections. When done orally it is processed by the liver. I had one injection and one 3 set series of NAD absorbed through the skin. Seems to work that way. I do notice some results with NAD but I am taking 500 mg and also with 100 mg of pterostilbene which is supposed to make it more available....I just read that study so maybe the fact that Siromilous suppresses NAD is less important if it is not so absorbed. I plan on getting another injection when I head back to Florida and will try to get a couple of them. THe NAD which is absorbed through the skin I am not sure if that works any better then the pills... but it is fairly cheap....

      Reply Like
  • In 28 years IAS never had an issue and there’s no need to distrust the supply chain. However we’ve halted RapaPro sales in the meantime until the results are in and we will take steps accordingly when we have them.

    Reply Like 1
      • Ozone8
      • Ozone8
      • 1 mth ago
      • 1
      • Reported - view

      CSC That seems like a prudent action, thank you. Please let us know when you have a definitive analysis. I would still like to order.

      Reply Like 1
  • Some of you might find this article...and perhaps the book "Bottle of lies" of interest. I listened to a podcast with the author.... frightening! Sadly, at the moment, I would not trust any offshore supplier...or their tests... Unless the testing was done by a reputable body in the USA or Western Europe. The history of generic drug fraud is long and deep. That said... Big Pharma and their patent-protection and extortion prices an obscenity. I'm back to paying $310 per month for Brand name (Rapamune) in Canada... Sigh!  I'm not sure of the solution... but I am 100% certain I was the victim of drug fraud... cynically initiated by someone...

    https://www.statnews.com/2019/07/22/indian-pharmaceutical-industry-drug-quality-charges/

    https://peterattiamd.com/katherineeban/

    Reply Like
    • Steve Roedde $310 per month for rapamune or sirolimus is 60 1mg pills if you if you use the goodrx coupon app. That save me a lot, and it is free. I agree India is prone to fraud.

      Reply Like
    • are we there yet ...Sadly I don't think GoodRx applies in Canada. I did look yesterday. Further, I doubt my prescription by a Canadian MD will be valid in the USA. Thanks for the suggestion! I appreciate the intent.

      Reply Like
    • Steve Roedde ... understood... I have heard of problems with Canada’s health system with pricing structures and bureaucratic rationing of critical treatments.

      Reply Like
    • are we there yet , Actually I am really happy with our system. Rapid access and treatment if you are ill, and no $ charges.  No "denial's by insurance companies. No bankruptcies as a result of catastrophic illness.

      .... As a senior, drugs are "free" (paid for through taxes, so those with the bad fortune to be ill are not penalized... we all share the burden.... but occasionally there is a glitch. If I was a renal transplant patient, there would be no cost to me. Nearly all Medications are available (almost always at a much lower cost than in the USA because of hard-bargaining by our health-care system)... but in this case, Biocon has chosen not to supply to the Canadian market. It's usually simple if the FDA has already approved a generic, but for some reason they are not interested... possibly due to market size.

      There is a mechanism for rapamycin to be covered.... but its a bit bureaucratic... but I'll pursue it.

      Reply Like
      • Iðunn
      • Iunn
      • 4 wk ago
      • 1
      • Reported - view

      are we there yet There are problems with every healthcare system on earth. The problems with Canada's system get amplified greatly in the United States because of the many economic interests a single-payer system would disrupt. Canadians are happier with their system than Americans are with theirs, and that includes people who have lived in each others' countries.

      Reply Like 1
      • Danmoderator
      • skipping my funeral
      • dantheman
      • 4 wk ago
      • 1
      • Reported - view

      A friend who grew up in Budapest during the 70's-90's is convinced his mother died of cancer because of the health care system. Sure it was nationalized - free - but to actually get the service you wanted, or any service, you had to pay the MD on the side. I'm sure it's different now, but agree no system is perfect. 

      Reply Like 1
    • Steve Roedde your Canadian Rx will NOT be accepted in the US. However, you might want to check out Qualytude.com, whose cofounder Sajad Zalzala is a physician who is reportedly licensed in all 50 states as well as Ontario. This is a newly launched telemedicine service catering to people who need Rxs for Metformin, Rapamycin, Dasatanib, etc.

      I don't know the pricing structure as yet and so can't vouch for it, but have met an officer and it seems to be a genuine effort to make access to these anti-aging drugs available to everyone.  

      Good luck.  

      Reply Like
      • garland
      • garland
      • 4 days ago
      • Reported - view

      Louise B Andrew the link Qualytude.com does not work......can you repost with the correct link thanks

      Reply Like
    • garland sorry about that. It is a "creative" spelling, no "u" (e.g. qalytude) 

      See https://www.cnbc.com/2019/10/06/sajad-zalzala-launched-qalytude-which-is-dedicated-to-anti-aging.html

      Reply Like 1
  • An interesting article. It seems that Biocon is the only company where deficiencies have not been discovered.... but India seems a bloody nightmare... And China worse. https://www.statnews.com/2019/07/22/indian-pharmaceutical-industry-drug-quality-charges/

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  • Steve Roedde I just joined this forum because I want to thank you for your posts in this thread. I have gone through two bottles of RapaPro myself. I haven't noticed any subjective effects (or sides), which isn't all that surprising, but I wasn't sure whether it was real and given the information you've provided, it appears that I wasted a lot of money on it.

    Thanks for standing your ground and calling them out. I am glad you are ok despite not using a real product.

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    • Luc Vareilles  Thanks so much. I believe truth is the only thing that matters... besides love....whatever that is.

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    • Luc Vareilles , I’ve used the RapaPro, as well as the MetPro ( Metformin), and just received some DasaPro ( dasinitib ), all manufactured by Profound Products .  I hope these were legitimate, as the company seemed reputable , and haven’t wasted lots of money!

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  • I just heard a new way to cycle NAD with Rapa by using the patches.... you take the rapa and then wait two days and then do 3 patches every other day of the NAD.... that way the NAD goes directly to the blood stream and is not processed by the liver from what I understand. I do know that one study found that NAD is processed by the liver if it taken orally. So it does not get directly to the organs when taken orally according to this study.  And interesting enough Serotonin seems to be a major contributing or causation factor for it when processed through the liver.....so you would do 12 patches a month along with the rapa....so as to get benefits directly to the organs without and processing by the liver and seems to circumvent the rapa problem...

    Reply Like
  • Reference RapaPro

    Official response from Profound Products.

    Profound Products take any negative review seriously because our unblemished reputation for supplying the highest quality products has been hard won over many years, however we know that a good reputation can just as easily be lost by a single allegation on a public online forum alleging that our products are placebos.

    Due to recent concerns from a customer, based upon their blood test results, they determined that there was no active Rapamycin ingredient in the RapaPro product.

    As this has never happened before, we immediately withdrew this product from sale from all resellers whilst we undertook our own investigation.

    We identified the product batch in question and sent a sample to an independent laboratory for analysis.

    The independent laboratory reported back that the product sample provided did indeed contain the active ingredient ‘Rapamycin’, however the amount of active ingredient per unit was lower than we had originally specified for manufacture.

    We therefore followed this report up with the compounding pharmacy who contract manufactured RapaPro and they undertook their own investigation. They reported back that their initial determination was that there had been an unprecedented formulation error and subsequently the incorrect product strength had been delivered to us.

    The product we commissioned for manufacture was specified to contain 5mg of Rapamycin per unit, whereas the independent laboratory test results established that RapaPro contains 3.25mg of Rapamycin per unit.

    We are pleased that this was brought to our attention as a result of this customers vigilance and Profound Products have instigated new procedures on the back of this aberration to ensure that such an occurrence should never happen again.

    Reply Like 1
    • CSC They better show some damn good proof that the next batch actually contains 5mg. I'm pissed off I wasted money on two bottles + the two shipping/wire fees for my orders. I was trying to low dose it too, so I was truly using baby doses once a week.

       

      Steve Roedde Thanks again for what you did. You saved me from wasting money on more bottles I was about to order.

      Reply Like
    • If IAS truly wants to remain credible, they would send free or discounted bottles to those of us who purchased RapaPro.

      Reply Like 1
    • Luc Vareilles i agree!

      Reply Like
      • Ozone8
      • Ozone8
      • 2 wk ago
      • Reported - view

      CSC Is the current batch of RapaPro being sold now on IAS actually 5 mg?

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  • As the Rapa-Pro is currently out of stock at IAS, I just ordered some Siromus (generic for Rapamune) at a fairly reasonable price. I've used this pharmacy (Indian)also many times in the past, for antibiotics , skin care products, and once for Tacrolimus ,(a topical immunosuppressant).  All have worked well, and hoping the Siromus will too.  Tablets are 1 mg each and are discounted the more you buy.

    Reply Like
      • Ozone8
      • Ozone8
      • 2 days ago
      • Reported - view

      angie4life Would you mind naming this pharmacy, and the price for the sirolimus?

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    • Ozone8 I’ve used All Day Chemist for years for products I can attest to be legit , as they worked as intended. Create an account and use your checking account to pay ( I’ve never had any issues with this ).  You fill out a form where there are some questions and a spot to upload an Rx , but I just skip over that part and place the order without problem.  It does take 20 plus days to arrive .  They have excellent customer service as well . Price for Siromus  1 mg tabs is $100.00 for 30 tabs, $200.00 for 60, and $260.00 for 90 tabs. They are at a reduced price right now .   Hope this helps !

      Reply Like
      • Ozone8
      • Ozone8
      • yesterday
      • Reported - view

      angie4life Thanks for the information. We will check out All Day Chemist. I'm a little concerned about providing bank account information but it's good to learn you've never had a problem.

      Reply Like
    • Ozone8 very welcome !

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