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Re: Which Rapamycin brand to buy versus which to avoid?
No to Biocon! I titrate based on Rapamune via Pfizer and find Biocon to be ~15% the claimed dose!
GEdwards
GEdwards
3 yrs ago
3
Rapamycin Discussion
Reported - view
Re: Dr Peter Attia on Rapamycin. Now 6 mg/week.
@GEdwards no mouth sores etc
GEdwards
GEdwards
3 yrs ago
1
Rapamycin Discussion
Reported - view
Re: Dr Peter Attia on Rapamycin. Now 6 mg/week.
I take at age 67, 3-4mgs a week with 6-8ozs of white grape fruit juice for an effective dose of ~9-15mgs.
GEdwards
GEdwards
3 yrs ago
1
Rapamycin Discussion
Reported - view
Re: Fisetin to Clear Senescent Cells
@Arizona Kid It may depend on if you have issues.....I heard from Dr. Attia that the son of the discoverer of Rapamycin that got it to novartis was beset with cancer and took 1mg a day.....…
GEdwards
GEdwards
3 yrs ago
1
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@Aka Loo yes and it can spike lipids a…
GEdwards
GEdwards
3 yrs ago
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@Arizona Kid I've read that a single 20mg dose is enough to stop mTOR1 for almost a full week but I don't believe that's thought to be ideal..... As mild to moderate suppression is sufficient to…
GEdwards
GEdwards
3 yrs ago
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@GEdwards As far as rapamycin, mTOR1 is said to be exquisitely sensitive to Rapamycin while mTOR2 (associated primarily with the innate immune system) is far less so affected.…
GEdwards
GEdwards
3 yrs ago
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@Arizona Kid
GEdwards
GEdwards
3 yrs ago
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
"Colored (pink and red) grapefruit pulp contains lower amounts of the furanocoumarin derivatives that cause pharmacokinetic interactions than white grapefruit pulp " ( https://pubmed.ncbi.nlm.nih.…
GEdwards
GEdwards
3 yrs ago
1
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
Bioperine is to (flavonoids) Tumeric or Fisetin etc what white grapefruit juice is to Rapamycin or Dasatinib......about a 3x increase in bioavailability.....…
GEdwards
GEdwards
3 yrs ago
1
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@Dan Nave hello, after some research I've found that bioperine potentiates flavanols.... Like fisetin and Q. The primary way to potentiate Dasatinibis taking it with grape fruit juice (white works…
GEdwards
GEdwards
3 yrs ago
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@JGC likely best to do this monthly or every 6 weeks!
GEdwards
GEdwards
3 yrs ago
Self-Experimentation
Reported - view
Re: Sources for inexpensive prescription Rapamycin
@Van Hi, tried Biocon india and was disappointed. Pfizer Sirolimus and the one Dr. Green sourced out of Kentucky work well! My severe hands arthritis respond to it but Biocon....…
GEdwards
GEdwards
3 yrs ago
1
Rapamycin Discussion
Reported - view
Re: Sources for inexpensive prescription Rapamycin
@are we there yet I'm in houston as well, following Dr. green's regimen for 3.5 years and would like to ask if you could share the Dr.s name you use? Many thanks!
GEdwards
GEdwards
3 yrs ago
2
Rapamycin Discussion
Reported - view
Re: Fisetin to Clear Senescent Cells
@Moonlitnight @Moonlitnight Hi MLNight,. Understood about cost having been laid off due to CV19 and my company being sold for assets. I never know the varying restrictions and just saw my nephew and…
GEdwards
GEdwards
4 yrs ago
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@Moonlitnight If you can make the trip to La Guardia and UBER out to him in Littleneck it is worth the time....stay in a local hotel near by if need by, I have....seen him for 3 years.....…
GEdwards
GEdwards
4 yrs ago
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@JOHN @JOHN Saw Dr Green the first time 3.5 years ago.....glad I had made the trip....just had appt with him 3 weeks ago....referred a few new patients to him....…
GEdwards
GEdwards
4 yrs ago
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
Hmmm...can you redo the link to the FB Israeli study...seems to be broken
GEdwards
GEdwards
4 yrs ago
Self-Experimentation
Reported - view
Re: Rapamycin self-experimentation
I think a reply will require a source for the 14% . Perhaps 14% is the amount he should have given what dose he takes. I personally have been taking 3mg sirolimus per week with Grape fruit juice…
GEdwards
GEdwards
4 yrs ago
4
Self-Experimentation
Reported - view
Re: Sources of dasatinib
I have just seen that Dr. Alan Green recommends 50mg twice a day for three days and 1500mg Fisetin...three days.... I have no info on his references for this dosing.
GEdwards
GEdwards
4 yrs ago
Senolytics Discussion
Reported - view
Re: Sources of dasatinib
@Patrick McHargue so ideally I'd have someone knowledgeable about metformin review the 'study'....I forwarded one to a very well know pathology about senolytics vs teleome re s and heard back that…
GEdwards
GEdwards
4 yrs ago
Senolytics Discussion
Reported - view
Re: Rapamycin in Mexico
I got it from hospital pharmacy throu my wife's niece... Was not readily available in retail pharmacies at the time
GEdwards
GEdwards
4 yrs ago
Rapamycin Discussion
Reported - view
Re: Rapamycin self-experimentation
@djmichel I wonder if this discussion has reviewed the differences in the innate vs the adaptive immune response and exactly what the sirolimus affects?…
GEdwards
GEdwards
4 yrs ago
1
Self-Experimentation
Reported - view
Re: Rapamycin self-experimentation
@Tam Hi ....I had the libido drop off awhile back...and due to an issue my son has I went to check and T was 230.....clinically low....got a script for T (Androgel at the time but using other…
GEdwards
GEdwards
4 yrs ago
2
Self-Experimentation
Reported - view
Re: High quality, affordable rapamycin (and other anti-aging meds)
@Mark Thimineur Hi, the source of the 'rapamycin' I got was Biocon and I found that it did not appear to have the 1mg dose as stated simply from the reaction I get from my arthritis of my hands.…
GEdwards
GEdwards
4 yrs ago
1
Announcements
Reported - view
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GEdwards
GEdwards
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