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Slower Biological Aging In People On A Calorie Restricted Diet
https://www.youtube.com/watch?v=vQOTkkCVAJU&t=1s
michael lustgarten
michael_lustgarten
3 yrs ago
85
General Discussion
Microbes Affect The Hallmarks Of Aging: Mitochondrial Dysfunction (Part II)
The Hallmarks of Aging are well established, but what is less discussed is the impact of microbes. Viruses, including SARS-CoV-2 and HSV-1 cause mitochondrial dysfunction-more specifically,…
michael lustgarten
michael_lustgarten
3 yrs ago
35
General Discussion
Just joined this site. So I am concerned about how I am aging.
Just joined this site. So I am concerned about how I am aging. I have just recently read about the effects of stress and how it damages your health and leads to premature aging.…
CHRIS
CHRIS.2
3 yrs ago
58
General Discussion
Microbial Products Affect the Hallmarks Of Aging: 1) Mitochondrial Function
The Hallmarks of Aging are well established, but what is less discussed is the impact of microbes and/or microbial products. The bacterial metabolite, LPS, increases during aging,…
michael lustgarten
michael_lustgarten
3 yrs ago
46
General Discussion
Metolazone
Has anyone read this article and have any thoughts? Are there any of drugs that do anything similar that have been discussed? Thanks https://www.osaka-cu.ac.…
Stevan Lieberman
Stevan_Lieberman
3 yrs ago
33
General Discussion
ISRIB Reverses Age-Related Mental Decline
https://elifesciences.org/articles/62048 Thoughts on this?
Anthony Koury
Anthony_Koury
3 yrs ago
1
reply
54
Last reply
Dorian Gray
3 yrs ago
General Discussion
Life Extension's Bio-Fisetin
I have read that this product is 25% more bioavailable than most other Fisetin products. I spoke with Life Extension and they said for purposes of addressing senolytic cells,…
Robin Maisel
Robin_Maisel
3 yrs ago
2
replies
295
Last reply
Endless
3 yrs ago
General Discussion
Rapamycin dosing 10-30 mg discussion
This was posted on Twitter by @agingdoc1 in an attempt to elevate the discussion around rapamycin ( the thread is here: ). On Twitter, after reading each portion you keep clicking on the content to…
agingdoc
agingdoc
updated
3 yrs ago
127
1
General Discussion
Need more emphasis on diet
I was disappointed to read through the current age reversal protocol promoted here, and it seems to be focused on expensive "magic pills". There was some mention of calorie restriction,…
Bruce Hamilton
Bruce_Hamilton
5 yrs ago
22
replies
463
3
Last reply
albedo
3 yrs ago
General Discussion
Man stopped aging !!!
Damn ! Even when it happens in front of our eyes doctors are clueless ! https://www.odditycentral.com/news/the-curious-case-of-a-32-year-old-man-who-looks-like-a-14-year-old-boy.…
Peter North
Peter_North
3 yrs ago
8
replies
344
1
Last reply
Peter North
3 yrs ago
General Discussion
Crispr Blindness Patient Outcome?
See https://apnews.com/article/17fcd6ae57d39d06b72ca40fe7cee461. I can find no follow-up on the patient outcome. Have results been published?
Dan Star
Dan_Star
3 yrs ago
28
General Discussion
What alternative clinics or strategies should be taken into account for pancreatic cancer Patients ?
Because cancer is directly associated with aging I would like to ask in this forum, what are some of the alternative clinics and treatment strategies I could look into, regarding pancreatic cancer.…
JPA
JPA
3 yrs ago
21
replies
131
Last reply
Michael
3 yrs ago
General Discussion
New Senolytics Targeting ß-Galactosidase
The standard way of identifying senescent cells in vitro is to stain a tissue biopsy with a dye that turns the enzyme ß-galactosidase a dark blue, and then counting the population of blue cells as…
JGC
Retired Professor of Physics
JGC
3 yrs ago
56
2
General Discussion
Reversing Parkinson's disease with HGH
Anyone?
Michael
Michael.1
3 yrs ago
2
replies
45
Last reply
Michael
3 yrs ago
General Discussion
Quercetin and dihydroquercetin
Hello everyone, I wonder about the differences of these two supplements. I've heard about the toxicity and lower positive effects of quercetin in comparison with dihydroquercetin.…
Gleb Merkurev
Gleb_Merkurev
3 yrs ago
51
General Discussion
Dr. Sinclair claims he reversed his Horvath clock by 29 years!
Go to 8:45 in this video. Said his biological clock was 60 and he reduced it to 31 by changing his life style. https://www.youtube.com/watch?v=QRt7LjqJ45k&t=8m45s Either he is lying or he is doing…
Jimmy
Jim_N
updated
3 yrs ago
22
replies
813
Last reply
Staffan Olsson
3 yrs ago
General Discussion
Sirolimus and covid
I take rapamycin (sirolimus) and read as much as I can find. So far I have not heard of anyone taking sirolimus getting covid. Is this significant? Suppression of mtor1 blocks or impedes cell viral…
are we there yet
are_we_there_yet
3 yrs ago
2
replies
112
Last reply
Curtis Smith
3 yrs ago
General Discussion
Source for NR
Hey all, Anyone recommends a source for NR? I used to buy from GeneX Formulas but they're out. I thought they can just online a few of those reaction chambers like they have at the local brewery and…
Chan
Chan
4 yrs ago
5
replies
206
1
Last reply
Jerry
3 yrs ago
General Discussion
Bontac obtained several invention patent issued
Bontac obtained several invention patent issued by the United States Patent and Trademark Office.Check us The three newly authorized U.S. invention patents are related to NMN Powder and NADH Powder…
Bontac
Bontac
3 yrs ago
2
replies
41
Last reply
Michael
3 yrs ago
General Discussion
Metformin in practice
I started Metformin with Rx (due to genetic defects for glucose and glucose control that is no longer optimal - plus the aging benefits) according to the Life Extension protocol.…
Dan
moderator
skipping my funeral
dantheman
updated
5 yrs ago
24
replies
796
1
Last reply
alstroemeria
3 yrs ago
General Discussion
Pure SUBLINGUAL NMN Powder (Micronized ) Bontac Eva Supplier
NMN Bontac uses stabilized NMN that will not degrade at room temperature.Buy Pure SUBLINGUAL NMN Powder From Bontac ,Competitive Price of NMN Powder will be offered if you buy bulk NMN Powder online.…
Bontac
Bontac
updated
3 yrs ago
1
reply
75
Last reply
Michael
3 yrs ago
General Discussion
Azithromycin kill/eliminate 97% senescent cells
I assume we're gonna need to get an rx if we're going to self experiment? 11/28/18 "Publishing in the journal Aging (US), a team from the University of Salford's Translational Medicine Laboratories…
mark
mark
updated
5 yrs ago
24
replies
1079
2
Last reply
Michael
3 yrs ago
General Discussion
Rapamycin Dosing lengthy discussions
Though it is not medical advice, I thought you may be interested in this, out of interest: 1) Gigantic thread, dozens of pages long at: https://www.longecity.…
Agingdoc1
Agingdoc1
3 yrs ago
112
1
General Discussion
Preventive Genetic Testing
What genetics tests would you recommend for the purpose of understanding your vulnerabilities - i.e. risks for conditions that might impact your lifespan or healthspan?…
Adrian M
Adrian_M
3 yrs ago
24
General Discussion
Longevity or quality ?
Many celebs ( including Elon Musk ) quick answer to how long they want to live is " 100 " ! Any one can tel me why ? They probably never seen or met a person over 70 ..Never mind 80 and 90 ....…
Peter North
Peter_North
3 yrs ago
1
reply
59
Last reply
Peter North
3 yrs ago
General Discussion
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AMPK Activation
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