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Re: Rejuvant? @Fred Cloud I don't recall the venue (maybe ARDD?), but I do recall a talk by Steve Horvath in which he reported on the DNAm clock readings for various tissue samples from the same human individual.…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- 1
- General Discussion
- Reported - view
Re: Rejuvant? @Staffan Olsson You wrote: "I don’t know which clock Rejuvant used." The Rejuvant clock used only 13 methylation sites, while Horvath-based clocks use several hundred.…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- 3
- General Discussion
- Reported - view
Re: Rejuvant? @Chuck Frasher The P stands for Piper Nigrum in the form of Swanson BioPerine ($2.86 for 60 x 10 mg caps). It is intended to increase bioavailability of flavenoids like Fisetin and Quercetin by…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- 1
- General Discussion
- Reported - view
Re: Where To Find Affordable But Quality Anti Aging LED Face Masks? @Fred Cloud Thanks for the reference. It would appear from the paper that in redox situations where electron transfer is marginal, an infrared photon can supply enough energy to push the reaction to…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- 1
- General Discussion
- Reported - view
Re: Where To Find Affordable But Quality Anti Aging LED Face Masks? @Fred Cloud Sorry again. I didn't mean to be offensive. Do you have reference links indicating that anything but heating is going on when IR light interacts with cells? (Incidentally,…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- 1
- General Discussion
- Reported - view
Re: Where To Find Affordable But Quality Anti Aging LED Face Masks? @Fred Cloud Sorry, Fred. I'm a retired Physics Professor. Light IS electromagnetic radiation!
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- General Discussion
- Reported - view
Re: Where To Find Affordable But Quality Anti Aging LED Face Masks? For me, LED Masks give off a faint odor of Snake Oil. I am surprised that non-ionizing electromagnetic radiation at relatively low intensities would provide any beneficial effects to aging cells,…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- 1
- General Discussion
- Reported - view
Re: Anti-Aging Self-Experiment with Epitalon (AEDG) @Tkit Thanks for the warning. Khavinson does a lot of self-promotion, but he does seem to have journal publications presenting good results of administering his peptides.…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Rejuvant? @Jimmy2 OK, I have now read the Buck Institute AKG paper and watched two of the Lithgow interviews on Modern Healthspan. I also watched some other videos on YouTube about the Buck Institute's AKG…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- General Discussion
- Reported - view
Re: Rejuvant? @Jimmy2 What's the evidence that "if you combine AKG with Metformin, it won’t reduce DNAm age" (but presumably will otherwise)? Fred Cloud said that AKG shows life extension effects because it…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- General Discussion
- Reported - view
Re: Rejuvant? @Jimmy2 Maybe I'm just paranoid, but I think "trust but verify" is a good strategy when dealing with commercial bio-tech testing outfits. In that context,…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- 3
- General Discussion
- Reported - view
Re: Rejuvant? @Fred Cloud @allen_rosenberg I don't understand why you guys are continuing to buy and take AKG, when Jimmy2's self experiment (see above) indicated that taking the expensive Rejuvant's AKG-Ca for 4…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- 1
- General Discussion
- Reported - view
Re: Rapamycin Cost @Chuck Frasher The Antiaging Store has been "out of stock" of their RapaPro for many months. I'm not sure that they are still in business.
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Rejuvant? @Pablo Reinaldos López OSK stands for three of the four "Yamanaka Factors", four proteins designated by the acronyms OCT4, SOX2, KLF4, and c-MYC (OSKM). There is no "dosage" involved.…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- 1
- General Discussion
- Reported - view
Re: Anti-Aging Self-Experiment with Epitalon (AEDG) EPITALON TEST UPDATE 1: My wife and I just completed the first month our 4-month Epitalon self-test. We took sublingual Epitalon from April 1-15, then restarted on May1-2 (yesterday and today).…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @Andrew Whitfield The bitterness is suspicious. To be really sure, you need to have a sample tested by a lab that does HPLC-mass-spectroscopy. Fisetin has a molecular mass of 286.…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- 1
- Senolytics Discussion
- Reported - view
Re: Can snorting fisetin improve bioavailability and is it safe? Probably snorting Fisetin would improve its bioavailabilty, but it would take a lot of such snorts to reach the level needed for senolytics. Let's say (as a guess) that putting Fisetin powder in…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- Senolytics Discussion
- Reported - view
Re: Fisetin to Clear Senescent Cells @Jack Black Thanks for the heads-up. Here's the LINK to her discussion. The problem is that she didn't give any help in actually finding a lab that will tell you the quantity of dihomo-15d-PGJ2 in a…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @GEdwards I am doubtful that senescent cells build up fast enough to make it worth doing a set of senolytic sessions every month or 6 weeks. However, this is at present a matter of opinion,…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @garland Last Thursday (4/22/2021) I did the third of three D+F+P senolytic sessions at about 3 PM in the afternoon (about the same time that I had done the first D+F+P session on the previous…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- 2
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @garland Thanks for the heads-up. I am 2/3 of the way through our latest senolytic session, but for the next phase on Thursday, I'll do 100 mg of Dasatinib.…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Fred Cloud My 3-session spacing with two off-days in between is done because Dasatinib is involved. When we did BioPerine+BioFisetin last year, I did not space the senolytic sessions and we did 3…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells D+F+P Side Effects with BioFisetin Yesterday my wife and I did a senolytic session for the first time since September-2020. We took 10 mg of BioPerine,…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- 3
- Self-Experimentation
- Reported - view
Re: GlyNAC @Staffan Olsson BulkSupplements.com also sells NAC powder, but it's a bit more expensive: $50/kg.
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Gamma-Linolenic Acid (GLA), Blood Autophagy, and Phenotypic Age @Jimmy2 Another anti-aging bubble burst!☹️ Perhaps the blood autophagy effect requires a larger dose than 400 mg/day. Or perhaps the problem is GLA insolubility and low bioavailability.…
- JGC
- Retired Professor of Physics
- JGC
- 3 yrs ago
- 1
- Self-Experimentation
- Reported - view

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Retired Professor of Physics

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Joined: Mon Aug 13 01:22:01 UTC 2018

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