Categories

How to enable Javascript

Latest Posts

Re: Fisetin to Clear Senescent Cells @Allen Papers in the literature indicate that BioPerine greatly enhances the bioavailability of the flavonoid Curcumin (which is contained in turmeric).…
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Longevity Achieved @Richard Brook Congratulations, Richard! And ignore those guys. Computer-based messaging is a "hot" medium and offensive stuff easily creeps in by accident.…
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- 2
- Self-Experimentation
- Reported - view
HGLA and GLA as Senolytics
In an interview posted online by Tufts Now, Dr. Christopher Wiley of Tufts University describes his discovery that dihomo-gamma-linoleic acid (DGLA) is a powerful senolytic.…
- JGC
- Retired Professor of Physics
- JGC
- updated 2 yrs ago
- 3replies
- 213
- Self-Experimentation
Re: Fisetin to Clear Senescent Cells There is a paper to be presented at the upcoming meeting of the American Aging Association (July 20-23) in which the researchers do one single dose of D+Q senolytics (D: 5 mg/kg + Q:…
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- 3
- Self-Experimentation
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @Fred Cloud Interesting question. I would think that once beta-gal is present, it would not easily go away, even if the SASP was temporarily stopped. I note that in a recent Foresight Institute…
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- Senolytics Discussion
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @Fred Cloud You wrote: "I am simply saying it is quieting the cells temporarily rather than killing them off." Research either published or presented at ARDD 2020 shows that,…
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- 1
- Senolytics Discussion
- Reported - view
Re: Replacing Hormones to Optimal Levels @Sharon Smith I hesitate to venture into the waters of optimal female hormone levels, but I would like to point out that Life Extension offers comprehensive female hormone tests for about $225.
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- Self-Experimentation
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now @Fred Cloud Katcher was talking about initially using E-5 on pets, particularly dogs, to extend their regrettably short lives. I recommended a like-minded vet in Southern California to him for this…
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- 1
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now @Burgundy Summer Until last week I had five items on my list of potential ways of obtaining a significant epigenetic reset to a younger DNAm age. They were:…
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- 2
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now @Winslow James Foster True, but in their publication on plasma dilution in mice, they did not even bother to measure the effect on DNAm age. I "make assumptions without data review" because that…
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now @Winslow James Foster The plasma dilution treatment may be at an early stage, but I think two things are pretty clear: The Conboy plasma dilution treatment provides only minimal epigenetic…
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- 3
- General Discussion
- Reported - view
Re: Fisetin to Clear Senescent Cells @garland You wrote: "I also read several studies that questioned whether it is a good idea to get rid of all our senescent cells? It seems the have some useful purpose." I recently watched Dr.…
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- 3
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @garland On Monday and Tuesday (July 5 & 6, 2021) we did another session of D+F+P senolytics (now taking 10 mg of BioPerine 5 minutes before the Dasatinib and BioFisetin).…
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Aneil You have identified a real problem for those of us doing senolytic self-experiments, i.e., that there is not presently a good way of measuring the senolytic cell population before/after the…
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- 3
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Aneil In the blood lab tests we did, I wanted to provide inputs for my Levine PhenoAge spreadsheet calculation, so we used Life Extension's Complete Blood Count (CBC) / Chemistry / Lipids Panel…
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- Self-Experimentation
- Reported - view
Re: A Spreadsheet for Calculating Your Levine Phenotypic Age New Spreadsheet Link There have been problems accessing this spreadsheet from DropBox, and also from MS Cloud, where someone named Karen recently replaced it with a blank file!…
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- Assessing Biological Age
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now @Winslow James Foster You said: "While I did achieve my lowest methylation age reduction of all experimental treatments tried, the Conboys and Kiprov discount this measurement.".…
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- 1
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now @Burgundy Summer As I understand it from my conversation with Dr. Kiprov, one would come to San Francisco and have 2 plasma dilution sessions spaced with an off-day in bethween.…
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- 1
- General Discussion
- Reported - view
Re: The Conboy Plasma-Dilution Treatment is Available Now @Fred Cloud You said: "Katcher's methylation treatment is supposed to be permanent and never wear off, but I also think it is working by a completely different process".…
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- 2
- General Discussion
- Reported - view
Re: Which Rapamycin brand to buy versus which to avoid? @John A couple of years ago I had some Dasatinib bought from BonHoa in India (and manufactured in Sri Lanka) tested at a US laboratory by HPLC followed by mass spectroscopy. It was the real thing.…
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- 3
- Rapamycin Discussion
- Reported - view
The Conboy Plasma-Dilution Treatment is Available Now
Recently, watching a video interview of Irina Conboy, I became aware that Conboy plasma-dilution for humans is available in San Francisco and Miami from the medical practice of Dobri Kiprov, MD,…
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- 136replies
- 1213
- 3
- General Discussion
Re: Fisetin to Clear Senescent Cells @Staffan Olsson @chuck_stanley OK, to summarize, it would appear that the short-duration (~15 minute) bio-enhancement effect of taking Bioperine is that it stimulates gut cells to release…
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Dan Nave I don't know enough anatomy, but it is my understanding that the Perine has to get into the bloodstream to interfere with the production of the digestive enzymes.
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @chuck stanley I looked up the Piperine half life on the web and found this: "Serial blood samples were collected and plasma piperine concentrations were determined using HPLC.…
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- Self-Experimentation
- Reported - view
Re: Can snorting fisetin improve bioavailability and is it safe? @Robert Uomini I meant "Kirkland". Have a look at the interview that Dr. James Kirkland did for the Foresight Institute at this LINK. He discusses the virtue of "burst" doses of D+Q and/or Fisetin…
- JGC
- Retired Professor of Physics
- JGC
- 2 yrs ago
- Senolytics Discussion
- Reported - view

1 3 4 5 6 7 19 Next

Back to top

JGC

JGC

Retired Professor of Physics

Seattle

452
591
16

Joined: Mon Aug 13 01:22:01 UTC 2018

Follow

http://faculty.washington.edu/jcramer/