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Re: Fisetin to Clear Senescent Cells @Staffan Olsson Question: When you "dissolved" the Dr's Best Fisetin in avocado oil, did it actually dissolve (so that the liquid became clear) or did you just have a colloidal suspension of the…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Staffan Olsson This morning we did our 3rd BioPerine (10 mg) + Fisetin-in-olive-oil (2 g) session. I feel quite alert and well and have been working to good effect on a book rewrite.…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells New Fisetin Senolytic Session It has been about 30 weeks since our last senolytic sessions, which were done last January. This morning my wife and I each took 10 mg of BioPerine,…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- 3
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Staffan Olsson Your thoughts about quercetin and inflammation are interesting. I think it's important to measure as much as possible the effects of self-administered senolytic treatments.…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Staffan Olsson It seems to me that if a senolytic session is actually working, is should produce a transitory feeling of unwellness that might last up to a day or so.…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- 3
- Self-Experimentation
- Reported - view
Re: How to increase the bioavailability of Fisetin @Paul Tozour Yes, apparently Amazon sells suppository molds, and one can fill these with coconut oil sandwiched with the supplement of interest, solidify them in the freezer, and insert away.…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- 2
- Self-Experimentation
- Reported - view
Re: How to increase the bioavailability of Fisetin @Dan Nave Senolytic research with mice indicates that there is a threshold all-at-once dose of Fisetin, below which there is not much action in clearing senescent cells,…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: How to increase the bioavailability of Fisetin @djmichel I bought the 100 g of Fisetin for $196 including shipping from vitaspace.com, which seems to be located in New York. I was dealing with a person named Peter. The URL is https://www.…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Hair regrowth @Danny A Google search on GcMAF turns up a whole host of warnings about fraud, cancer quacks, contaminated injectables, retracted papers, and stern warnings.…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- 1
- General Discussion
- Reported - view
Re: Is Young Plasma Really a Worthwhile Treatment for Aging? @Danny Smith Interesting. I note that colostrum GcMAF creams are available for sale on the Internet, with prices ranging from $89 (for 1,500 ng) to $798 (for 15,000 ng) per jar,…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- General Discussion
- Reported - view
Re: Is Young Plasma Really a Worthwhile Treatment for Aging? @Danny Smith I note that colostrum MAF supplements are indeed available on the Internet, but they are rather pricey. A quick web search indicates that they seem to cost $3.70 to $7.…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- General Discussion
- Reported - view
Re: How to increase the bioavailability of Fisetin @Staffan Olsson Phosal 50 seems to be a mix of 50% phosphatidylcholine and 50% propylene glycol, both of which can be ordered from Amazon. In particular, they sell phosphatidylcholine for $14.…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: A Spreadsheet for Calculating Your Levine Phenotypic Age If you look in the discussion about Fisetin as a senolytic you will find HERE a spreadsheet snippet showing a comparison of a number of age estimates from aging.…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- 3
- Assessing Biological Age
- Reported - view
Re: How to increase the bioavailability of Fisetin @Jesper de Meeuw Where did you get the Phosal 50? A quick web search showed some information but no sources.
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Dan Nave Thanks for the references, particularly "Interactions between CYP3A4 and Dietary Polyphenols". Just to drop the other shoe, I note that Fisetin and Quercetin are both classifiable as…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: How to increase the bioavailability of Fisetin @Danh Tran My wife and I did three senolytic sessions involving about 5,000 mg of Fisetin each last October/November (as described elsewhere in this Forum), and we have taken none since.…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- 2
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Dan Nave I just ordered 100 gm of >98% pure powdered Fisetin from VitaSpace for $190 plus $6 shipping. That's $0.19 for 100 mg, still a lot better than $0.47 per 100 mg from Drs Best.…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Monitoring Senescent Cell Clearance with Cytokine Levels @murray flewelling asked "is there any Fisetin product that you have heard to be one of the best ?" Most of the capsules available on the Internet come from the same source.…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Dasatinib @Dan Nave I think the request for prescription depends on the salesman that BonHoa assigns. Some people have been asked and others not. I was asked for a prescription,…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- 2
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Dan Nave Have you bought supplements from Alibaba? How does the payment arrangement work?
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @BobM I notice that Amazon also has Trillium powder-form Fisetin for $59.88 for 50 grams. That's about $0.12 for 100 mg, as compared to $0.47 per 100 mg from Drs Best.…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- 2
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Iðunn The digestive enzyme CYP3A4 in the small intestine is what is normally limiting the bioactivity of Dasatinib and the other drugs. From the web searches I have done,…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells That's an interesting point. I found an article HERE that discusses the effect of grapefruit juice. It says: "Compounds in grapefruit called furanocoumarin chemicals are the cause of the increased…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- 3
- Self-Experimentation
- Reported - view
KLOTHO and GABA for Brain Enhancement
There is an article in today's NY Times about the wonders of KLOTHO, a recently discovered brain hormone that, at least in mice, increases lifespan, wards off Alzheimer's,…
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- 20replies
- 483
- 5
- General Discussion
Re: Thymus aging mitigation strategies Question: If you clear half of your old T cells and later replace them with new ones, does that mean that you may lose immunity to past diseases that the old T cells "remember"?
- JGC
- Retired Professor of Physics
- JGC
- 5 yrs ago
- Thymus Regeneration
- Reported - view

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Retired Professor of Physics

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