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Re: Rapamycin Cost @Ellis Toussier I don't think Blagosklonny would say he is an expert on Rapamycin so much as an expert on mTOR. He has postulated and published a theory that aging is driven by mTOR not shutting…
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Oral NAD; wasting our time and money? And yet, the mice in Sinclair’s lab drank water with nmn and showed significant change
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- 1
- General Discussion
- Reported - view
Levels of senescent cells correlates with death?
Interesting study https://www.nature.com/articles/s41467-019-13192-4
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- 1reply
- 187
- Senolytics Discussion
Re: Rapamycin Cost @Ellis Toussier since you passed up my suggestion to engage with Mikhail Blogoslonny on Twitter, I queried his thinking on HGH. Continuously dosing HGH is akin to dosing with hormones or nutrients.…
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- 2
- Self-Experimentation
- Reported - view
Re: Metformin @Karl if there is any drug that has any evidence in humans it’s Metformin
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- 1
- AMPK Activation
- Reported - view
Re: Rapamycin self-experimentation @Sam Biller looks like you have a 15 year predicted improvement in DNAm Age from the spreadsheet posted on this website! I started rapa Dec 1 and also did a dasatanib/quercetin one time treatment.…
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- 2
- Self-Experimentation
- Reported - view
Re: Rapamycin self-experimentation @Sam Biller looks like all the biomarkers going in the right direction per the Levine spreadsheet
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @David C You don't mention quercetin which is often recommended for senolytic treatments - do you take it or just the fisetin? and what is your dosage per Kg of weight?
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- Senolytics Discussion
- Reported - view
Re: Fisetin to Clear Senescent Cells @karl kuffner don’t know about effective but taking high doses of fisetin, quercitin or Danasitab on an empty stomach keeps me running to the toilet all day
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Rapamycin Cost @Ellis Toussier have you read the work of Mikhail Blogosklonny? He seems to have researched rapamycin better than anyone. He is quite accessible on twitter and readily answers questions.…
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- 2
- Self-Experimentation
- Reported - view
Glucose level a proxy for sirolimus level?
Some have suggested a blood test is needed to measure rapamycin levels. I wonder if glucose levels can serve as a proxy for sirolimus? my fasting blood sugar is normally in the high 70’s.…
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- 4replies
- 204
- Rapamycin Discussion
Clomid to raise Testosterone?
Anyone try use Clomid to raise T? Seems to stimulate the body to produce its own testosterone. Testes don’t shrink and can still produce sperm. Seems like a better idea than the gels
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- 13replies
- 369
- 1
- Questions & Answers
Re: Intermittent fasting and rapamycin In mice it does https://academic.oup.com/biomedgerontology/article/75/1/4/5373089
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- 1
- General Discussion
- Reported - view
Re: NAD+ Patches For those who got NAD patches from Archway what did the doctor prescribe? Was it 400 mg of NAD or something else? Was the 8 hour patch for higher dosage or something else?
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- NAD+ Restoration
- Reported - view
Re: NAD+ Patches @Steve Harris The ocean is pretty neutral so there is on driver to push ions into you. However, if you add some voltage to salt water...
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- NAD+ Restoration
- Reported - view
Re: Senolytics just finished second dosage of dasatinab and quercetin. First time had a slight headache and hours of diarrhea. Had taken on an empty stomach which I've learned is not good for anything I take.…
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- 5
- Self-Experimentation
- Reported - view
Via Longitudinal study
Anyone hear anything about this? Signed up over a month ago and never received any information
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- 2replies
- 31
- Questions & Answers
Re: NAD+ Patches Anyone try the NAD patches from https://www.qalytude.com/
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- NAD+ Restoration
- Reported - view
Re: A Spreadsheet for Calculating Your Levine Phenotypic Age used the spreed sheet to order importance of variable without age for me(I think it is a correlated factor plus it is uncontrollable). Used a 10% improvement to look at the age improvement generated.…
Attachment
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- Assessing Biological Age
- Reported - view
Re: Bill Faloon's Recent Blood Test Results @albedo Testosterone is not one of the input variables for the predictor, so predicting female from other blood markers
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- 1
- Test Results Discussions
- Reported - view
Re: Bill Faloon's Recent Blood Test Results @Max Peto thanks sent an email
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- Test Results Discussions
- Reported - view
Re: Bill Faloon's Recent Blood Test Results @albedo aging AI1.0 prediction is 44 AI3.0 is 28 year old female
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- Test Results Discussions
- Reported - view
Re: Bill Faloon's Recent Blood Test Results @Max Peto How is it possible to see the email you mentioned from Bill? Is there something to join?
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- Test Results Discussions
- Reported - view
Re: Bill Faloon's Recent Blood Test Results I put these into the DNAmPhenoAge spreadsheet elsewhere on this site and it gives a 10 year reduction in predicted age.
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- 1
- Test Results Discussions
- Reported - view
Re: Bill Faloon's Recent Blood Test Results This doesn’t tell me much without some context. Is there a place where Bill says what he does-drugs, supplements, fasting, diet, exercise, etc.?
- Paul Beauchemin
- Paul_Beauchemin
- 4 yrs ago
- Test Results Discussions
- Reported - view

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Paul Beauchemin

Paul_Beauchemin

All over America in my RV

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Joined: Sun Dec 15 22:30:53 UTC 2019

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Retired after 40 years at DuPont
MS Chemical Engineering