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Re: Dr. Sinclair claims he reversed his Horvath clock by 29 years!
@Curtis Smith Rejuvant use Calcium Alpha-ketoglutarate (Ca-AKG). I have not tried that supplement yet. But the Ca-AKG effect made me curious. I have tried L-arginine-alfa-ketoglutarate (AAKG) 4 gr…
Staffan Olsson
Staffan_Olsson
4 yrs ago
General Discussion
Reported - view
Re: Fisetin to Clear Senescent Cells
I have made a similar experience. Based on nothing but my own personal experience I prefer to take Fisetin on empty stomach in the morning (after having taken some black pepper or piper longum…
Staffan Olsson
Staffan_Olsson
4 yrs ago
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@garland Sounds like strong effect. Did you take fisetin alone or did you take it with quercetin?
Staffan Olsson
Staffan_Olsson
4 yrs ago
1
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@garland Metabolism is a very complex process and at this stage it is not possible at this stage to say something certain about how fisetin and quercetin influence each others biological actions…
Staffan Olsson
Staffan_Olsson
4 yrs ago
Self-Experimentation
Reported - view
Re: Glucosamine instead of Metformin and Rapamycin?
I write this post because I have read that AMPK activation could possibly be detrimental in neurological some diseases. (not knowing if it is correlation or a possible causation).…
Staffan Olsson
Staffan_Olsson
4 yrs ago
AMPK Activation
Reported - view
Re: Fisetin to Clear Senescent Cells
@Dan Nave Hi! I have this link to a paper from 2010 that discuss how to Improv the oral bioavailability of beneficial polyphenols through designed synergies.…
Staffan Olsson
Staffan_Olsson
4 yrs ago
Self-Experimentation
Reported - view
Re: Rejuvant?
@Paul Beauchemin Thank you for the links. The you tube interview was great. I think they don't recommend taking AKG with multivitamins since the combination might cancel out each other's positive…
Staffan Olsson
Staffan_Olsson
4 yrs ago
General Discussion
Reported - view
Re: Paul's self experimentation
@Peter H. Howe Thank you for the information. I did not know that metformin can decrease T.
Staffan Olsson
Staffan_Olsson
4 yrs ago
Self-Experimentation
Reported - view
Re: Rejuvant?
@Iðunn AS far as know they published it yesterday in cell metabolism. But not the full paper. And it is not a free version. Cell-metabolism Short Article| Volume 32, ISSUE 3, P447-456.…
Staffan Olsson
Staffan_Olsson
4 yrs ago
General Discussion
Reported - view
Re: Rejuvant?
@Iðunn This is the full text. https://www.biorxiv.org/content/10.1101/779157v1.full.pdf
Staffan Olsson
Staffan_Olsson
4 yrs ago
General Discussion
Reported - view
Re: Rejuvant?
@David H Thank you David! Much appreciated.
Staffan Olsson
Staffan_Olsson
4 yrs ago
General Discussion
Reported - view
Re: Rejuvant?
@Paul Beauchemin I found this paper about CaAKG. Calcium-Alpha Ketoglutrate is to find. Have someone else here had better luck? https://www.sciencedirect.…
Staffan Olsson
Staffan_Olsson
4 yrs ago
1
General Discussion
Reported - view
Re: Treatment for Reducing Arterial Plaque and Imflammatory Cells:
@Peter H. Howe Thank you for the reference to World of molecules. it indicate that fisetin might useful in more ways than acting as a senolytic compound.
Staffan Olsson
Staffan_Olsson
4 yrs ago
General Discussion
Reported - view
Re: Treatment for Reducing Arterial Plaque and Imflammatory Cells:
@Peter H. Howe Peter. I am happy you find Fisetin useful. I do to. some seem to have the idea that you can benefit from fisetin in different ways. One way is to use the procedures that most of us…
Staffan Olsson
Staffan_Olsson
4 yrs ago
1
General Discussion
Reported - view
Re: Treatment for Reducing Arterial Plaque and Imflammatory Cells:
@Peter H. Howe Peter, I am very curious about how people use fisetin. And nice to hear that fisetin works well for you. Can you share how you use fisetint?…
Staffan Olsson
Staffan_Olsson
4 yrs ago
1
General Discussion
Reported - view
Re: Treatment for Reducing Arterial Plaque and Imflammatory Cells:
@BobM Here is another perspective on how to reverse atherosclerosis. There is research aiming at reversing athrerosclerosis by resetting the microbiome. They have done it successfully on rats.…
Staffan Olsson
Staffan_Olsson
4 yrs ago
General Discussion
Reported - view
Re: Treatment for Reducing Arterial Plaque and Imflammatory Cells:
@Fred Cloud Thank you Fred. I do other interventions for now, but any progression in the field of plaque reduction is very interesting to me.
Staffan Olsson
Staffan_Olsson
4 yrs ago
1
General Discussion
Reported - view
Re: Treatment for Reducing Arterial Plaque and Imflammatory Cells:
@Fred Cloud Thank you for your response. I wonder if you can share your experiences of edta chelations. After 75 chelations your personal experience and the health benefits of the treatment is very…
Staffan Olsson
Staffan_Olsson
4 yrs ago
General Discussion
Reported - view
Re: Treatment for Reducing Arterial Plaque and Imflammatory Cells:
I have no personal experience of it, but one therapy that some people say can reduce plaque is Vascular Rejuvenation using EDTA. Here is a link: https://brain.forever-healthy.…
Staffan Olsson
Staffan_Olsson
4 yrs ago
General Discussion
Reported - view
Re: Recent Plasma-Replacement Results
@JGC @Larry The results from the conboy's group are fascinating. https://www.aging-us.com/article/103418/text And I found this comment on> https://www.instagram.…
Staffan Olsson
Staffan_Olsson
4 yrs ago
1
Young Plasma Infusions
Reported - view
Re: Glucosamine instead of Metformin and Rapamycin?
@Zisos Katsiapis Here is a link to research that show decreased all-cause mortality among those who took Glucosamine. " A population-based prospective cohort study included 495 077 women and men…
Staffan Olsson
Staffan_Olsson
4 yrs ago
AMPK Activation
Reported - view
Re: Recent Plasma-Replacement Results
@Chan I am happy that you appreciate the information that we share here on this forum. Parabiosis and its offspring - how to rejuvenate the human body by using blood factors is an exciting field.…
Staffan Olsson
Staffan_Olsson
4 yrs ago
Young Plasma Infusions
Reported - view
Re: Fisetin to Clear Senescent Cells
@JOHN I have tried several ways to administer fisetin. I have mixed fiestin in the same way as they did with rats in the el mayo study, I have used home made rectal suppositories,…
Staffan Olsson
Staffan_Olsson
4 yrs ago
1
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@Fairy8i8 @Joe smith yes the half life of fisetin is short. But its effects are long lasting because the effect of the "fisetin punch" produce a structural change in the human body by knocking out…
Staffan Olsson
Staffan_Olsson
4 yrs ago
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@Fairy8i8 @Joe smith I lookad at that interview some time ago and I remember that Fayey mentioned that when broccoli sprouts (or supplements) activate the Nrf2 pathway the pathway will stay…
Staffan Olsson
Staffan_Olsson
4 yrs ago
1
Self-Experimentation
Reported - view
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Staffan Olsson
Staffan_Olsson
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