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Re: Rapamycin and a possible link to accelerated Alzheimer's Disease
@Marcus Asaro I said "Amyloid theory of Alzheimer's seems to have been founded on doctored data." So was the data (images) doctored, or not? https://www.science.…
- saxxnviolins
- 2 yrs ago
- Rapamycin Discussion
- Reported - view
Re: Low-Dose Oral Minoxidil for Hair Regrowth
The return of spam.
- saxxnviolins
- 2 yrs ago
- Self-Experimentation
- Reported - view
Re: Photo evidence that the experiment is working
Looks good - re nasolabial folds. Too bad all of it is in Instagram; not viewable by non-members like me - no facebook, no instagram, no twitter.
- saxxnviolins
- 2 yrs ago
- Self-Experimentation
- Reported - view
Re: Introduction to senolytics
Thank you. Very illuminating.
- saxxnviolins
- 2 yrs ago
- Senolytics Discussion
- Reported - view
Re: Rapamycin and a possible link to accelerated Alzheimer's Disease
Amyloid theory of Alzheimer's seems to have been founded on doctored data. https://www.science.org/content/article/potential-fabrication-research-images-threatens-key-theory-alzheimers-disease
- saxxnviolins
- 3 yrs ago
- 2
- Rapamycin Discussion
- Reported - view
Re: Introduction to NAD+
@Van Cheap d-ribose from NJ here. https://shopbestnaturals.com/products/best-naturals-d-ribose-powder-1-lb?_pos=1&_sid=6d579a5f6&_ss=r
- saxxnviolins
- 3 yrs ago
- NAD+ Restoration
- Reported - view
Re: SGLT2
@Rod C Thanks for the info on white bean extract. Motivates me to cook callos Madrileños and substitute the chick peas with white beans. For acarbose mimetics,…
- saxxnviolins
- 3 yrs ago
- General Discussion
- Reported - view
Re: SGLT2
@Karl Waiting for my rder of schisandra.
- saxxnviolins
- 3 yrs ago
- General Discussion
- Reported - view
Re: SGLT2
Those who want to go the herbal route, see below: https://www.sciencedirect.com/science/article/pii/S2667031322000112 Another study showed that methanol extract of root of Sophora flavescens Aiton…
- saxxnviolins
- 3 yrs ago
- General Discussion
- Reported - view
Re: Combination of rapamycin, rifampicin and allantoin in fruit flies
Although rapamycin and rifampicin are mentioned, the product is made of natural ingredients - AKG, fisetin, etc. That is the basis of the points below.…
- saxxnviolins
- 3 yrs ago
- 1
- General Discussion
- Reported - view
Combination of rapamycin, rifampicin and allantoin in fruit flies

A commercial product is being marketed with the following talking points. https://novoslabs.com/why-combinations-of-longevity-drugs-are-the-future/ In one study,…
- saxxnviolins
- 3 yrs ago
- 2replies
- 53
- 1
- General Discussion
Re: Who Else taking Acarbose for longevity?
You posted this more than a year ago. So what have been the effects/benefits?
- saxxnviolins
- 3 yrs ago
- 2
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells
Additional info on fisetin: https://www.frontiersin.org/articles/10.3389/fchem.2019.00697/full Recent in vitro studies have given a mechanistic insight into how fisetin inhibits the target of the…
- saxxnviolins
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells
@Staffan Olsson Thank you. There seem to be many natural substitutes for metformin or acarbose, for the calorie-restriction mimetic effect. Berries are more palatable; but leaf powder is cheaper.…
- saxxnviolins
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Sea squirts, mussels and longevity
I forgot the link to the commercial product. http://www.oilsfats.org.nz/wp-content/uploads/2016/02/Dawn-Scott-Nelson-talk-Nov-2016.pdf
- saxxnviolins
- 3 yrs ago
- Self-Experimentation
- Reported - view
Sea squirts, mussels and longevity

https://neurosciencenews.com/aging-sea-squirts-20570/#:~:text=They%20found%20that%20the%20supplements,impairments%20in%20the%20aging%20brain. As the article suggests,…
- saxxnviolins
- 3 yrs ago
- 5replies
- 190
- Self-Experimentation
Re: Fisetin to Clear Senescent Cells
@Chris M Agreed. I stood corrected by Moonlitnight.
- saxxnviolins
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells
@Juan Daw Dr. Miller has yet to publish his study about fisetin. Yet, people are already concluding fisetin's benefits have been discredited. I would want to read the study and compare with the…
- saxxnviolins
- 3 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells
@Moonlitnight Yes. I stand corrected. My fault, not the keyboard's.
- saxxnviolins
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells
@Juan Daw The best results come from Rapamycin and Acarbose (alpha gluosidase inhibitor). I am not ready to try drugs yet, so I will try a combination of Ashwaghandha with some natural alpha…
- saxxnviolins
- 3 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells
@Moonlitnight Waiting for the paper to be published. https://www.youtube.com/watch?v=42PzfNs9egA&t=0s Dr. Miller talks about two substances (minute 1:12:13) he is excited about,…
- saxxnviolins
- 3 yrs ago
- Self-Experimentation
- Reported - view
Re: Anyone notice better dental health on rapamycin?
@Dorian Gray Below are three studies of the use of azithromycin to regenerate alveolar bone, complete with x-rays of the patients. The Australian (Hirsch) and the Japanese (Fujise) had only three…
- saxxnviolins
- 3 yrs ago
- 1
- Rapamycin Discussion
- Reported - view
Re: Rapamycin vs Metformin
@Karl Sorry. I meant mimetic.
- saxxnviolins
- 3 yrs ago
- AMPK Activation
- Reported - view
Re: Rapamycin vs Metformin
Sorry. I meant mimetic.
- saxxnviolins
- 3 yrs ago
- AMPK Activation
- Reported - view
Re: Rapamycin vs Metformin
Withaferin is also an analogue of rapamycin, second to the antibiotic geldamycin. With the rapamycin classifier, the most significant hit was geldanamycin (Fig. 2B).…
- saxxnviolins
- 3 yrs ago
- AMPK Activation
- Reported - view

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