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Re: Rapamycin vs Metformin
@Staffan Olsson The supplemental table shows the following combinations, and their similarity to Metformin. There is no data on percentages per combination. Withaferin is ashwagandha.…
Juan Daw
saxxnviolins
2 yrs ago
AMPK Activation
Reported - view
Re: Online med clinic dedicated to fighting age-related disease (in US)
Post was ten months ago. Has it launched yet? What tests would be administered?
Juan Daw
saxxnviolins
2 yrs ago
AMPK Activation
Reported - view
Re: Fisetin to Clear Senescent Cells
It seems Rapamycin is also considered a senomorphic by some researchers. https://academic.oup.com/biomedgerontology/article/76/6/1144/6126488
Juan Daw
saxxnviolins
2 yrs ago
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
Looks like Metformin has senomorphic effects. Is that the reason for the anti-aging effects? https://www.frontiersin.org/articles/10.3389/fbioe.2021.730813/full
Juan Daw
saxxnviolins
2 yrs ago
1
Self-Experimentation
Reported - view
Re: GlyNAC
Glycine alone seems to extend lifespan. As mentioned earlier glycine is the one amino acid studied thus far in which supplementation has been shown to extend the lifespan of mice,…
Juan Daw
saxxnviolins
2 yrs ago
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
Wrong link https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247629/
Juan Daw
saxxnviolins
2 yrs ago
Self-Experimentation
Reported - view
Re: Fisetin to Clear Senescent Cells
@Moonlitnight Modulation of Cellular Senescence by Tocotrienols In contrast to the pro-senescence activity displayed in cancer cells, there is substantial evidence that T3 may act as senescence…
Juan Daw
saxxnviolins
2 yrs ago
Self-Experimentation
Reported - view
Re: Longevity Achieved
" @Jonette Brook said: It is our intent to share our methods with the age reversal and longevity community our accomplishments and interact with like minded people That was six months ago.…
Juan Daw
saxxnviolins
2 yrs ago
1
Self-Experimentation
Reported - view
Re: Safe Rapamycin and Metformin mimetics
@UB Nrf2 increase can be achieved by intake of sulforaphane, found in cruciferous vegetables. There are many vidoes on this by Rhonda Patrick, interviewing Dr. Jed Fahey.…
Juan Daw
saxxnviolins
2 yrs ago
Self-Experimentation
Reported - view
Re: Safe Rapamycin and Metformin mimetics
Take a look at the below link. Withaferin A (ashwagandha) is a mimetic of both rapamycin and metformin.…
Juan Daw
saxxnviolins
2 yrs ago
1
Self-Experimentation
Reported - view
Re: Measuring biological age by the reaction of those around you
The triage theory of aging may support the title of this thread. Since looks are the least important for the organism, they would come last, in terms of repair.…
Juan Daw
saxxnviolins
2 yrs ago
Assessing Biological Age
Reported - view
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Juan Daw
saxxnviolins
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