Treatment for Reducing Arterial Plaque and Imflammatory Cells:
I would like to start this as a focused topic.
Background: I’m 69, have followed Bill Faloon / Life extension protocols for about 10 years. Doing the Dasatinib / Quercetin and Rapamycin treatments since mid last year. I have very low body fat, eat very healthy and have outstanding blood work. Model ldl/GSK triglycerides. Very low inflammatory markers.
Now I have 2 stints. Fixed 95 and 90% blockages in two main arteries. I was fortunate to go in to ER before some serious heart damage happened.
So digging into why: Plaque accumulation on the inner area of the artery wall.
So for me, figuring out how to REDUCE plaque seems like the biggest life extension action I can take. And I am sure this is true for many others.
Consulting with my heart doctor was not fruitful. He prescribed the cookbook set of meds: 10 mg of Lipitor, 40mg of Avorstatin, 61 mg aspirin, 75 mg Plavix (clopidogrel).
I got some good advise from folks on another forum herein. Found Avorstatin helps LDL/HDL but does nothing for plaque or inflammation. I’m now taking 40mg of Crestor, in place of the Avorstatin.
See Birmingham Medical News, New Plaque Study highlights Power of Crestor.
Very good!
Other: I’m looking to change Lipitor blood pressure med to Ramipril. This product seems to lower inflammation levels in the blood, whereas Lipitor does not.
Questions for discussion:
What else can we do to reduce plaque?
Is there something we are doing in our healthy protocols which causes more plaque buildup?
Cellular Inflammation in the Blood: how is this really measured? How do we reduce naturally? Do any of our senolytic treatments knock this down?
All: please pass along any good research things you have seen.
This is a great group!
Thank you!
BobM
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Hi Folks,
So I had my long awaited appointment with my new Cardiovascular Disease Prevention doctor at Mayo Clinic. A Top doc in this field. He reviewed all my data with me. Had spent some time in studying before our meeting. Said I was in the top 1% of people, given my data and what I was doing. Went on to say the most important measurement and goal for me should be reducing LDL to 30. I am now at 49. Am down from 72 a year ago. He rather summarized that all the other testing was noise.
He said I might need a cholesterol absorption blocking drug to get to that number.Ok, simple enough.
Now today I read the very interesting paper:
https://www.fightaging.org/archives/2020/08/reducing-ldl-cholesterol-is-the-wrong-target-for-cardiovascular-disease/I think this paper has a lot of merit, but tainted slightly by the expected future commercial side of the 2 research companies. Of course I will try this as soon as it’s available.
Still want to know how to measure progress... my new doc was not a big fan of CIMT testing. 🤨On the question of benefits from men giving blood: he said none.
Cheers to all!
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Hi Folks,
Yesterday I had a nice meeting with my naturopathic Dr. She is excellent. We discussed the past 6 months and all the labs etc.
She observed from my NMR blood tests, that my LDL size 19.8nm) was quite small and dense, and noted this was not good for my CVD (although all my other data was very good). You can have lots of large fluffy LDL - no problem. But this small stuff related to plaque buildup. Geese, you would have thought my 3 other MD doctors would have picked up on this!
Her suggested intervention for this was high dosing of niacin. Up to 2000 mg/day, taken together with fish oil. Easy enough!