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DNA methylation test
myDNAge has a $299 urine or blood test for DNA methylation, they're running a buy get one 50% off at the moment. Steve Perry recommends this company, I ordered a test and will let you know how it…
Dan
moderator
skipping my funeral
dantheman
5 yrs ago
27
replies
775
3
Assessing Biological Age
Re: UK and Anti-Aging
The defining characteristic of the US is its diversity and size. Pretty much everything is here on any spectrum you care to measure. I smile when I see people who think the US is this or that - it's…
Dan
moderator
skipping my funeral
dantheman
5 yrs ago
General Discussion
Reported - view
Re: FOX04
FOXO4 is a gene part of the FOXO group - FOXO3 is a famous longevity gene. Before any experimenting I'd suggest consulting your genetic test to see how you come out on that (I've got CT).…
Dan
moderator
skipping my funeral
dantheman
5 yrs ago
1
General Discussion
Reported - view
Re: Longo's fasting, DR, longevity conference
Dang it, missed this announcement. The main question I have - which may not easily be answerable, is balancing the various approaches. We have a palette of tools now to regulate mTOR and other aging…
Dan
moderator
skipping my funeral
dantheman
5 yrs ago
2
Announcements
Reported - view
Self testing regime.
Steve Perry has a great list of easy and cheap self administered biomarker assessments here. He believes that doing these things is meaningless unless you've got test results to back it up which I…
Dan
moderator
skipping my funeral
dantheman
5 yrs ago
7
replies
473
1
Test Results Discussions
Re: Rapamycin Side Effect
@Don LE recommends 500mg before each meal, with a protocol to start (250 once a day leading up to 500 each meal after a few weeks). Eventually it's suggested you can go to the maximum dose,…
Dan
moderator
skipping my funeral
dantheman
5 yrs ago
Self-Experimentation
Reported - view
Re: A Spreadsheet for Calculating Your Levine Phenotypic Age
Here's an useful small hack - put your numbers in and vary them to see how you can make your bio age go backwards and by what degree. For instance driving your glucose down by 10 points gives you an…
Dan
moderator
skipping my funeral
dantheman
6 yrs ago
2
Assessing Biological Age
Reported - view
Re: Whole genome sequencing for $700-750?
By the way for those who have signed up, with Veritas (and probably others) you can pay a small fee and get the raw XML data for your genome, in addition to the free formatted reports.…
Dan
moderator
skipping my funeral
dantheman
6 yrs ago
General Discussion
Reported - view
Re: Whole genome sequencing for $700-750?
@Ozone8 Wow, that went fast, sorry!
Dan
moderator
skipping my funeral
dantheman
6 yrs ago
General Discussion
Reported - view
Re: A Spreadsheet for Calculating Your Levine Phenotypic Age
@JGC thanks for the spreadsheet. FWIW I have Ptypic Age of 40.35 and est DNAm Age of 39.97 (I'm 53) - so by this measure I'm biologically 40, which is approximately what I would guess to be my…
Dan
moderator
skipping my funeral
dantheman
6 yrs ago
2
Assessing Biological Age
Reported - view
Re: GDF11 rejuvenation
Also I'd mention for those interested - this treatment is probably equivalent to parabiosis (transfusing with young blood). Except it's cheaper, but maybe not easier.
Dan
moderator
skipping my funeral
dantheman
6 yrs ago
Self-Experimentation
Reported - view
Air filtering (re: wildfires)
Friends, I'm a fan (ha ha) of air filtering and with these California wildfires have become more so. These fires are going to be an increasing feature of our lives, please protect your lungs.…
Dan
moderator
skipping my funeral
dantheman
6 yrs ago
2
replies
67
2
General Discussion
Re: NAD+ Patches
Note: through my doctor I'm ordering the patches from Archway, when you get a prescription you need to specify what duration patches (4 hour or 8 hour) and number of packs (6 patches to a pack).
Dan
moderator
skipping my funeral
dantheman
6 yrs ago
1
NAD+ Restoration
Reported - view
Re: Whole genome sequencing for $700-750?
BTW one benefit of a genome report like I got at Veritas - see if your provider does a drug report (Veritas does this). Since us anti-aging super-advocates are venturing into pharmaceuticals it can…
Dan
moderator
skipping my funeral
dantheman
6 yrs ago
General Discussion
Reported - view
Re: Whole genome sequencing for $700-750?
For anybody following this, Veritas Genetics, where I got my whole genome done, is running a sale for $199, first 1000 sign ups. Run quick if you want a great price.…
Dan
moderator
skipping my funeral
dantheman
6 yrs ago
General Discussion
Reported - view
Re: Rapamycin Side Effect
I posted elsewhere about this, but I'd remind people that if possible they should check they're CYP3A5 gene, available from Veritas Genetics and others.…
Dan
moderator
skipping my funeral
dantheman
6 yrs ago
1
Self-Experimentation
Reported - view
Re: Rapamycin Side Effect
@Don @are we there yet LEF has several good articles on Metformin, here and here. In this article Bill talks about dosing to build tolerance - start with 250 once a day, work up to 500 after a week,…
Dan
moderator
skipping my funeral
dantheman
6 yrs ago
Self-Experimentation
Reported - view
Re: Rapamycin Side Effect
In regards to the flu shot - I don't get it because I use getting sick as a biomarker of health. In this example, I haven't gotten the flu in many years.…
Dan
moderator
skipping my funeral
dantheman
6 yrs ago
2
Self-Experimentation
Reported - view
Cimetidine
Cimetidine for immune system modulation here LE article COPL Bill doesn't recommend it for daily use, but on occasion (for example in December for some individuals - not sure why that specifically,…
Dan
moderator
skipping my funeral
dantheman
6 yrs ago
109
1
Self-Experimentation
GDF11 rejuvenation
Has anybody here participated with GDF11 Rejuvenation? Results, experience?
Dan
moderator
skipping my funeral
dantheman
6 yrs ago
4
replies
262
1
Self-Experimentation
Re: Has anyone tested NAD+ blood levels yet?
@Deb63 How does one do so? AFAIK there are no simple clinical tests (e.g. blood) available yet.
Dan
moderator
skipping my funeral
dantheman
6 yrs ago
NAD+ Restoration
Reported - view
Re: Rapamycin in humans
@peterc No studies AFAIK. Don't forget carnosine (with an S) which is a LE recommended supplement for vegans/vegs as that is a substance you only get from meat.…
Dan
moderator
skipping my funeral
dantheman
6 yrs ago
Self-Experimentation
Reported - view
Re: Rapamycin in humans
@peterc Nope, it's not a problem with vegans! I was at the True North center (helping a friend get better) when a researcher came through and gave a talk, including about that result.…
Dan
moderator
skipping my funeral
dantheman
6 yrs ago
Self-Experimentation
Reported - view
Re: Rapamycin in humans
@peterc Agree, most supplements have no apparent effects. For me the only ones that do are CoQ10 (in large enough dose it does act as an upper), PtC (skin improves after a week of restarting),…
Dan
moderator
skipping my funeral
dantheman
6 yrs ago
Self-Experimentation
Reported - view
Re: NAD+ Patches
@Dennis Fink Not bad, but of course in a field rapidly changing (non linearly) it doesn't tell you much to use the previous researchers as case studies.…
Dan
moderator
skipping my funeral
dantheman
6 yrs ago
2
NAD+ Restoration
Reported - view
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