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Re: Intro to rapamycin
Been off this site for a while, went down a deep rapamycin rabbit hole. Just recently came out: https://drive.google.com/file/d/1CP-IUU5H3EzNHAyQMF3LQb6gotynT-et/view?usp=sharing
MAC
MAC
1 yr ago
1
Rapamycin Discussion
Reported - view
Re: Variability Among Horvath-type DNA Methylation Age Tests
JGC…why is Zymo “best replication of Horvath work”? I have done one epigenetic aging test (blood) so far, myDNAge; https://www.mydnage.com/ It came back 3.5 yrs younger than my CA of 56.…
MAC
MAC
3 yrs ago
Assessing Biological Age
Reported - view
Re: should rapamune be stopped for covid resurgence?
@linda Did you read the paper in the link? here is another: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834195/pdf/main.pdf The literature and few studies suggest it's "protective" for viral…
MAC
MAC
3 yrs ago
General Discussion
Reported - view
Re: should rapamune be stopped for covid resurgence?
https://www.thelancet.com/pdfs/journals/lanhl/PIIS2666-7568(20)30068-4.pdf I am on same regiment.
MAC
MAC
3 yrs ago
General Discussion
Reported - view
Re: Replacing Hormones to Optimal Levels
@Dorian Gray I workout daily at approx 4pm, just before my single meal of the day dinner. I do about 45 minutes of resistance exercise, and then immediately followed by 30 mins of high intensity…
MAC
MAC
3 yrs ago
1
Self-Experimentation
Reported - view
Re: Replacing Hormones to Optimal Levels
Amino acids do NOT potentiate or prevent muscle loss...resistance exercise does. I am not banking on any amino acid, other form of nutrition or testosterone to maintain/build muscle as I age.…
MAC
MAC
3 yrs ago
Self-Experimentation
Reported - view
Re: Replacing Hormones to Optimal Levels
@Sharon Smith sorry you misunderstood. My keto macros are 75% plant fats, 25% protein. What I meant is that my keto is based on plant fats (avocado, nuts, olive oil) not animal fats.…
MAC
MAC
3 yrs ago
Self-Experimentation
Reported - view
Re: Replacing Hormones to Optimal Levels
Wow. You are an inspiration Sharon! I am 56 yr old male started on exogenous testosterone 5 yrs ago, agree with your muscle building/health/longevity philosophy completely.…
MAC
MAC
3 yrs ago
1
Self-Experimentation
Reported - view
Re: Calorie Restriction, Eat Once Every Other Day (EOD Diet)
Do you have references on OMAD/epigenetic age in humans? In regard to OMAD not being "as fast" as say some other more extreme protocol, the key is to maintain the biggest epigenetic signal you can…
MAC
MAC
3 yrs ago
Self-Experimentation
Reported - view
Re: Calorie Restriction, Eat Once Every Other Day (EOD Diet)
Jimmy, you replied, but for some reason, it didn't populate the forum? I am taking the liberty to post your reply, and then I follow with a reply below.…
MAC
MAC
3 yrs ago
Self-Experimentation
Reported - view
Re: Calorie Restriction, Eat Once Every Other Day (EOD Diet)
To be clear, you're going to take your current weight stable calories/day, maintain them, but only eat EOD, INDEFINITELY? You will disappear, won't have much left to even draw blood for epigenetic…
MAC
MAC
3 yrs ago
1
Self-Experimentation
Reported - view
Re: My Journey To Reduce My Epigenetic Age
Science dosen't bend to impatience...and more data is only good, if truly determinant. But awesome you are using epigenetics to track your changes!
MAC
MAC
3 yrs ago
Assessing Biological Age
Reported - view
Re: My Journey To Reduce My Epigenetic Age
This is great info Jimmy. I did my first DNAage blood test in July 20, showed approx 3 yrs younger (I was 55). How old are you? There is some error/noise in the test of course.…
MAC
MAC
3 yrs ago
Assessing Biological Age
Reported - view
Re: Sources for inexpensive prescription Rapamycin
@Robert Olin I posted on this yesterday: https://forum.age-reversal.net/t/35hl3h8/rapamycin-cost-in-india
MAC
MAC
3 yrs ago
Rapamycin Discussion
Reported - view
Re: Rapamycin Cost in India
@Betty Bennett Certainly. At most it will just validate if there is any Siromilus in the dose. Impossible to infer anything else.
MAC
MAC
3 yrs ago
General Discussion
Reported - view
Re: Rapamycin Cost in India
@Betty Bennett I’ve just started on Rapamycin 2 months ago, sourcing from this outfit in Australia, 4 mg capsules. http://rapamycin.store They came recommended by another user on this forum.…
MAC
MAC
3 yrs ago
1
General Discussion
Reported - view
Re: DL001
Yes, I wrote to the author back when. He said many years away from FDA approval. Sigh.
MAC
MAC
3 yrs ago
Questions & Answers
Reported - view
Re: Recent Plasma-Replacement Results
@Fred Cloud I am homozygous H63D, mild HH. Picked up some iron knowledge on an iron forum. I never paid attention to iron until I found out I was apoe 3/4, including my HH status,…
MAC
MAC
3 yrs ago
Young Plasma Infusions
Reported - view
Re: Recent Plasma-Replacement Results
Fluctuates, but these are the results over the last 18 months when I did test for it: 34, 20, 45, 15, 37, 23 My last transferrin was 21%. As I've posted I believe elsewhere,…
MAC
MAC
3 yrs ago
1
Young Plasma Infusions
Reported - view
Re: Recent Plasma-Replacement Results
@Peter I donate blood every 8 weeks. According to Conboy (private communication), this is at most 10% of their mice work signal. Hey, every little bit helps!
MAC
MAC
3 yrs ago
1
Young Plasma Infusions
Reported - view
Re: Berberine
Anyone taking this improved bioavailability Berberine, dhBBR? Appears to be FAR superior to regular berberine for lipids/glucose/anti-aging? Only looking to add it as an anti-aging intervention,…
MAC
MAC
3 yrs ago
AMPK Activation
Reported - view
Re: Kidney Function Declines During Aging-Can It Be Reversed?
Sorry to hear of your CKD, any idea cause? Your switch to LCHF/OMAD, was that doctor mediated or on your own? There's a big difference between plant fat and animal fat based LCHF.…
MAC
MAC
3 yrs ago
Self-Experimentation
Reported - view
Re: Kidney Function Declines During Aging-Can It Be Reversed?
I am almost 56 yo male now. 3 yrs ago, at 53, eGFR was 103. Last month it was 95. The graph would suggest I am a approx. 30 yrs old, which is non sensical.…
MAC
MAC
3 yrs ago
1
Self-Experimentation
Reported - view
Re: Update on two dogs profiled in a 2016 CNN post about Rapamycin
@shane where I sourced my first foray into Rapamycin. 4mg doses. http://rapamycin.store/
MAC
MAC
3 yrs ago
Rapamycin Discussion
Reported - view
Re: Micro-Dosing Lithium for Life Extension - How to Divide 300mg Tablet?
I am a high exerciser, so was concerned Rapamycin would blunt or impact. I live in Canada, so visiting Dr Green out of the question COVID. My FMD, although he's heard of Rapamycin,…
MAC
MAC
3 yrs ago
2
Self-Experimentation
Reported - view
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MAC
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