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Re: Intro to rapamycin Been off this site for a while, went down a deep rapamycin rabbit hole. Just recently came out: https://drive.google.com/file/d/1CP-IUU5H3EzNHAyQMF3LQb6gotynT-et/view?usp=sharing
- MAC
- MAC
- 5 mths ago
- 1
- Rapamycin Discussion
- Reported - view
Re: Variability Among Horvath-type DNA Methylation Age Tests JGC…why is Zymo “best replication of Horvath work”? I have done one epigenetic aging test (blood) so far, myDNAge; https://www.mydnage.com/ It came back 3.5 yrs younger than my CA of 56.…
- MAC
- MAC
- 1 yr ago
- Assessing Biological Age
- Reported - view
Re: should rapamune be stopped for covid resurgence? @linda Did you read the paper in the link? here is another: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834195/pdf/main.pdf The literature and few studies suggest it's "protective" for viral…
- MAC
- MAC
- 1 yr ago
- General Discussion
- Reported - view
Re: should rapamune be stopped for covid resurgence? https://www.thelancet.com/pdfs/journals/lanhl/PIIS2666-7568(20)30068-4.pdf I am on same regiment.
- MAC
- MAC
- 1 yr ago
- General Discussion
- Reported - view
Re: Replacing Hormones to Optimal Levels @Dorian Gray I workout daily at approx 4pm, just before my single meal of the day dinner. I do about 45 minutes of resistance exercise, and then immediately followed by 30 mins of high intensity…
- MAC
- MAC
- 1 yr ago
- 1
- Self-Experimentation
- Reported - view
Re: Replacing Hormones to Optimal Levels Amino acids do NOT potentiate or prevent muscle loss...resistance exercise does. I am not banking on any amino acid, other form of nutrition or testosterone to maintain/build muscle as I age.…
- MAC
- MAC
- 1 yr ago
- Self-Experimentation
- Reported - view
Re: Replacing Hormones to Optimal Levels @Sharon Smith sorry you misunderstood. My keto macros are 75% plant fats, 25% protein. What I meant is that my keto is based on plant fats (avocado, nuts, olive oil) not animal fats.…
- MAC
- MAC
- 1 yr ago
- Self-Experimentation
- Reported - view
Re: Replacing Hormones to Optimal Levels Wow. You are an inspiration Sharon! I am 56 yr old male started on exogenous testosterone 5 yrs ago, agree with your muscle building/health/longevity philosophy completely.…
- MAC
- MAC
- 1 yr ago
- 1
- Self-Experimentation
- Reported - view
Re: Calorie Restriction, Eat Once Every Other Day (EOD Diet) Do you have references on OMAD/epigenetic age in humans? In regard to OMAD not being "as fast" as say some other more extreme protocol, the key is to maintain the biggest epigenetic signal you can…
- MAC
- MAC
- 1 yr ago
- Self-Experimentation
- Reported - view
Re: Calorie Restriction, Eat Once Every Other Day (EOD Diet) Jimmy, you replied, but for some reason, it didn't populate the forum? I am taking the liberty to post your reply, and then I follow with a reply below.…
- MAC
- MAC
- 1 yr ago
- Self-Experimentation
- Reported - view
Re: Calorie Restriction, Eat Once Every Other Day (EOD Diet) To be clear, you're going to take your current weight stable calories/day, maintain them, but only eat EOD, INDEFINITELY? You will disappear, won't have much left to even draw blood for epigenetic…
- MAC
- MAC
- 1 yr ago
- 1
- Self-Experimentation
- Reported - view
Re: My Journey To Reduce My Epigenetic Age Science dosen't bend to impatience...and more data is only good, if truly determinant. But awesome you are using epigenetics to track your changes!
- MAC
- MAC
- 1 yr ago
- Assessing Biological Age
- Reported - view
Re: My Journey To Reduce My Epigenetic Age This is great info Jimmy. I did my first DNAage blood test in July 20, showed approx 3 yrs younger (I was 55). How old are you? There is some error/noise in the test of course.…
- MAC
- MAC
- 1 yr ago
- Assessing Biological Age
- Reported - view
Re: Sources for inexpensive prescription Rapamycin @Robert Olin I posted on this yesterday: https://forum.age-reversal.net/t/35hl3h8/rapamycin-cost-in-india
- MAC
- MAC
- 2 yrs ago
- Rapamycin Discussion
- Reported - view
Re: Rapamycin Cost in India @Betty Bennett Certainly. At most it will just validate if there is any Siromilus in the dose. Impossible to infer anything else.
- MAC
- MAC
- 2 yrs ago
- General Discussion
- Reported - view
Re: Rapamycin Cost in India @Betty Bennett I’ve just started on Rapamycin 2 months ago, sourcing from this outfit in Australia, 4 mg capsules. http://rapamycin.store They came recommended by another user on this forum.…
- MAC
- MAC
- 2 yrs ago
- 1
- General Discussion
- Reported - view
Re: DL001 Yes, I wrote to the author back when. He said many years away from FDA approval. Sigh.
- MAC
- MAC
- 2 yrs ago
- Questions & Answers
- Reported - view
Re: Recent Plasma-Replacement Results @Fred Cloud I am homozygous H63D, mild HH. Picked up some iron knowledge on an iron forum. I never paid attention to iron until I found out I was apoe 3/4, including my HH status,…
- MAC
- MAC
- 2 yrs ago
- Young Plasma Infusions
- Reported - view
Re: Recent Plasma-Replacement Results Fluctuates, but these are the results over the last 18 months when I did test for it: 34, 20, 45, 15, 37, 23 My last transferrin was 21%. As I've posted I believe elsewhere,…
- MAC
- MAC
- 2 yrs ago
- 1
- Young Plasma Infusions
- Reported - view
Re: Recent Plasma-Replacement Results @Peter I donate blood every 8 weeks. According to Conboy (private communication), this is at most 10% of their mice work signal. Hey, every little bit helps!
- MAC
- MAC
- 2 yrs ago
- 1
- Young Plasma Infusions
- Reported - view
Re: Berberine Anyone taking this improved bioavailability Berberine, dhBBR? Appears to be FAR superior to regular berberine for lipids/glucose/anti-aging? Only looking to add it as an anti-aging intervention,…
- MAC
- MAC
- 2 yrs ago
- AMPK Activation
- Reported - view
Re: Kidney Function Declines During Aging-Can It Be Reversed? Sorry to hear of your CKD, any idea cause? Your switch to LCHF/OMAD, was that doctor mediated or on your own? There's a big difference between plant fat and animal fat based LCHF.…
- MAC
- MAC
- 2 yrs ago
- Self-Experimentation
- Reported - view
Re: Kidney Function Declines During Aging-Can It Be Reversed? I am almost 56 yo male now. 3 yrs ago, at 53, eGFR was 103. Last month it was 95. The graph would suggest I am a approx. 30 yrs old, which is non sensical.…
- MAC
- MAC
- 2 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Update on two dogs profiled in a 2016 CNN post about Rapamycin @shane where I sourced my first foray into Rapamycin. 4mg doses. http://rapamycin.store/
- MAC
- MAC
- 2 yrs ago
- Rapamycin Discussion
- Reported - view
Re: Micro-Dosing Lithium for Life Extension - How to Divide 300mg Tablet? I am a high exerciser, so was concerned Rapamycin would blunt or impact. I live in Canada, so visiting Dr Green out of the question COVID. My FMD, although he's heard of Rapamycin,…
- MAC
- MAC
- 2 yrs ago
- 2
- Self-Experimentation
- Reported - view

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