NAD+ Patches
I recently purchased NAD+ from the NAD treatment center in San Diego. I purchased the NAD+ patches, 6 each @ 400mg each. The patches are a electrophoresis type patch that uses a battery to drive the NAD+ into the skin. The six patches were $300.00. I spoke with Jennifer ( 944-623-7587 ext. 5) at the center who arranged telephone consultation with Dr. Milgram. The product was fulfilled by Archway Apothecary in Covington, La. I also purchased a NAD+ nasal spray which the Doc said goes directly to the brain. To date I have used three patches and continue to daily take NR. After completing the patches I will post my results/impressions.
Best,
David Michel
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Just saw a great article on research at Penn State using chewing gum to deliver vitamins ( https://medicalxpress.com/news/2018-10-gum-effective-vitamins.html#nRlv ). Sounds like what we need for getting NAD levels up in us older types!
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Dennis ..careful, many older people have some dental caps, and chewing gum can sometimes pull teeth caps off and Need a dentist to reseat them.
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I caught Bill Faloon in a recent talk saying offhand that they (Life Extension?) were investigating whether NAD patches were as effective as IV drips for older individuals who need more intensive treatment. His comment was that they would be reporting soon on that. He'll be talking in early Nov at his Church Of Perpetual Life YouTube channel, perhaps he'll give us an update on that.
https://www.youtube.com/watch?v=jj0MbRW2Muk
Patches are cheaper and easier than drips, if say Life Extension sold them I'd prefer taking that approach, even though I have a local clinic that will do a NAD drip for me.
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Dan Mc I just tried my first sublingual NMN lozenge (ProHealth 60x125 mg NMN, NAD precursor, $45) so we seem to have many options other than too expensive IV's as long as they do the job! Trying LEF NADH lozenges also. Looking for info comparing benefits of patches, nasal spray, lozenges!
Dan Mc "Alive by Nature" carries NAD powder for sublingual use - "PURE NAD+ Powder – 12 Grams Nicotinamide Adenine Dinucleotide $64.95". It seems we have a multitude of ways to go other than expensive electrophoresis patches and IV's if we can determine that they work as well! I have read that NAD itself is not very bioavailable so if anyone sees good research in this area let me know.
Alive by Nature says:
"NAD+ crosses the blood brain barrier to raise NAD+ levels in the hypothalamus which activates:
- Mood – Activates Neurotransmitters to enhance sense of well-being
- Increased Energy Expediture
- Decreased Appetite
This PURE NAD+ powder can be used sublingually (under the tongue) so it is absorbed directly to the bloodstream and is readily available to cells throughout the body.
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Dennis Fink Thanks for the information. Sounds like good options, of course the problem is we don't know if any of the actually raise levels better than the oral pills do, mainly because there isn't an easy blood test you can take yet. My wife and I are taking 250mg orally and are having the improved sleep benefit, but in our early 50's we don't know what steps we should take. There's an IV clinic locally that indicated they could do NAD+ for me, but I don't know, is that necessary? If LifeExtension determines that patches (or sublingual ...) work as or nearly as well as oral then I'll sign up.
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Dan Mc Right! I wouldn't think IV would be needed at your age. I can see Bill Faloon trying it in his 60's and I'm 74 so I doubt the 500-750 mg of NR is doing enough for me, thus the experimenting w/ lozenges and patches. Hoping I can get a lab test soon.
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Dennis Fink Thanks, yeah that's what I would think also, but Bill has mentioned "over 50" several times in this context in videos. Don't know, but anyhow we've been at this longevity game for 30 years so our stats are good so taking it slowly would seem to not be a bad approach.
I've been meaning to ask BrianMDelaney about this, I think I saw a YouTube video of him getting the drip and we seem about the same age. Brian any thoughts on a good age to start the drip (I think Brian is traveling so might be a while before he comes back)?
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Dennis Fink I just finished last week with 5 IV NAD+ infusions. I did six patches; two weeks later I did two IV's; had to travel for five days so I did a patch each day, and then finished with 3 IV's. That was last Fri. Today was a great day but the jury is still out. I did have three glutathione IV's which was the clinic's standard practice. Dan Mc
Dennis Fink Dan Mc I did 500 mg/day of the LEF NR for over a year with no noticeable effects
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Kerry I can't really identify any results from the patches since I use one during the day time and another at night and doing too many other things. As I mentioned elsewhere, the sublingual NMN seems to be showing the most evidence of benefit so far (Longecity).
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Dennis Fink Their price is now $69.99, plus shipping, plus TAXES. The total cost is over $80. Who charges taxes for supplements or medications? I'm looking for another source.
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Good article at (ttps://mehdium.com/neodotlife/the-anti-aging-habits-of-longevity-experts-b2f3997f3091) describing David Sinclair's use of NMN for his own anti-aging battle (and others).
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Dennis Fink Here's a link that works
I've seen Aubrey and Judy talk about their approach, or lack, before. I sometimes wonder if they really understand the differences between health span, mean or median life span, and maximum life span. Aubrey in particular seems to think "well since nothing I can do will increase (maximum) life span I won't do anything", without understanding that what we can individually do now can make an enormous difference in the other two.
To illustrate, not smoking won't increase the maximum life span of humanity, but it will greatly increase the median lifespan and the health span. So take any particular smoking individual, but choosing not too they could live an extra 30 years (still within the 120 year maximum span) in better health. That's huge!
Likewise alcohol is a poison - the science is very clear on that now, yet they both drink. OK that might not shave much off their own health or life span, or it might, especially when combined with other things they're doing or not doing.
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Dan Mc Agree Dan! I think David Sinclair is being a bit smarter than Aubrey at least when it comes to anti-aging supplement usage. I think Aubrey said his wife is 19 years his senior, I wonder if she uses anything. Surely she does!
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Dennis Fink Here is another interesting article from the NY Times on Life extension:
https://www.nytimes.com/2018/03/09/opinion/sunday/longevity-pritikin-atkins.html
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Not important but I think Aubrey and his wife separated and he's with somebody younger now.
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Dennis Fink Not bad, but of course in a field rapidly changing (non linearly) it doesn't tell you much to use the previous researchers as case studies. We were just getting our feet wet back then with decades between any energy being put into research efforts. Today there are new companies and projects popping up daily. In other words the rate of change of attention to longevity has been proceeding exponentially (or some other non linear variant)
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David Michel
Interesting article in NY Times. Antiaging gurus who die are a lesson in understanding that age reversal / attenuation is multifactorial and far from a hard science even now. Something we all should consider with reference to the rationality of signing up for cryonics.
I want to ask this forum about Deprenyl, which I started taking 5 mgs/day of last week, and is one of the first antiaging/brain enhancement molecules. I remember reading a very compelling book, "A Remarkable Medicine has been Overlooked" several decades ago, and wanting to try Deprenyl.
And now I find I can get it without a script and reasonably priced from International Antiaging Systems. I am holding off on trying the Rapamycin I got from IAS because I don't want too many conflating variables going on at once.
So, in order to report/learn about Deprenyl in this forum, do I start a new thread, as this is a different topic than NAD+ supplementation/mechanics?
Rudi Hoffman -
Rudi Hoffman so what have you observed taking Deprenyl?
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I live in Houston. Does anyone know of a longevity or rapamycin groupe that meets in the Houston area?
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are we there yet
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are we there yet I am also in Houston. I have researched groups (Facebook, Meet up etc) and have not been able to find anything. I would LOVE to find or start a group. My husband is not very interested in health and does not want to talk about my latest biohacking / anti aging learning and activities. Let me know if you are interested in starting up a group. Perhaps we could both reach out to contacts / facebook groups and see what interest there is? FYI, married 44 year old female.
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Endless It is really surprising to me, considering the size of the med center and the city of Houston, that there are not more longevity resources here. I am finding I am having to really piece things together (NAD here, peptides there etc) , and even look out of state for the treaments/modalities I am interested in. It's really frustrating.
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NAD can go with fisetin. In Houston I found no health food stores that carry fisetin, but I was able to get sprouts to custom order it and will get a 2 month supply in 4 days.
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are we there yet I have several different types of fisetin to choose from on Amazon but the concentrations are a guessing game for now! Since Dr. Green is impressed w/ it, I think it might be worth the cost.
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I purchase Trillium Fisetin from Amazon, 50 grams , provides 50 one gram servings. Comes with a one gram spoon. Cost is 50 dollars. See link
