GlyNAC

Juan Daw Agreed. I think the real question are what substances, in what amounts, when and how do they react to each other. We know lots of things that extend life, but we also know that taken incorrectly could kill us. Here is an article from 2017 which summarizes a long list of them: https://link.springer.com/article/10.1007/s13659-017-0135-9

Karl I take a constellation of substances targeting glutathione production, support of the mitochondria, brain health, folate cycle, skin and joints health, bone strength, and of course Rapa. 

No idea if this will extend lifespan, however quality of life has improved. My exercise performance is the best it's been in years. My memory is good and cognitive tests are way easier. Skin elasticity has improved by the equivalent of several years.

In short, whether I live to 95 or not I'm hopeful that my later years will be more active and fulfilling than might otherwise occur.

Stevan Lieberman Had the same positive impact on me. There's still a risk profile  however and why CJC and similar peptides are alternatives, esp for older people.

Stevan Lieberman I started with 1-2 ius daily for 6 months and maxed at 3-4 ius daily for the next 6 months. During one of the second 6 months, I took 6ius daily.

I then took a serostim break for 3- 6 months while experimenting with peptides: CJC, tb-500, bpc-157, etc... while also trying different versions of gh.

1. I began using the peptides after doing some more research on the dangers of using exogenous gh, as well seeing an increase in moles  & existing moles becoming darker -  which might have been coincidental. 

2. I began trying different versions of gh as serostim is so expensive.

My conclusion is serostim is an awesome product however, depending on your goals and age,  peptides might be just as effective. 

As an aside, only recently (one year next month) have I begun an elevated version of trt: 300 ml a week of sustanon.

Testosterone is by far the most efficacious exogenous product I've used. Everything from sleep, strength, focus, gaining size, etc...

Stevan Lieberman I initially tried gh to mimic Greg Fahys Triim Trial.

I used Metformin, GH and DHEA to see if it would reduce/reverse my gray hair as it did with one of his participants.  And it worked! 

Michael I suspect that either HGH or Testosterone in some form would give me the benefits of better sleep, mood, and well-being.  And, God knows I certainly do need those things.  However, I've avoided them because I've gotten the impression from what I've read that they would be counter-productive to living a healthier and possibly longer life.  Any thoughts?

Jay Orman I've read similar things so, I can't say it's not a consideration. I do know     when I turned 50, I started to feel and look old - almost as if a switch was flipped. It was such a drastic and alarming change, I began researching things like those mentioned above and joining forums like this. My conclusion is QUALITY of life is at the moment, as important to me as longevity and the quality of my life has certainly improved.

Michael Yes, I see your point. 

Michael It has been a couple of years and I am now revisiting old topics of interest.  If you have the time and don't mind sharing information I would like to know what you've been using consistently and any benefits versus side effects you've noticed.  If there is something you tried, but found of no use, I would like to know about that, too. 

As for me, I use Rapamycin and I've found a few things occasionally useful for sleep and energy from the standard drugs category, but so far my venture into Peptides has shown nothing. 

BPC 157 and TB 500 don't seem to work for me yet, but I'll try a little while longer before I give up.  I also tried ITPP (myo-inositol trispyrophosphate) and found it to be of no use.  However, the area of peptides does look interesting.  It's just a matter of finding a safe source with a legitimate product and the best, safest way of dosing, not to mention accurate data versus someone simply trying to sell me snake oil.  Some of those snake oil salesmen appear to be the most honest, trustworthy people you'd ever know and peptides are expensive.  So, I try to be cautious in this area.   

TRIIM, TRIIMX, HGH and CJC-1295, etc.?   I've forgotten the exact protocol for Thymus Rejuvenation, but the choice of HGH over a peptide is intriguing.  It makes me assume Fahy knew that HGH was the best choice over a (any) peptide? 

Thanks for your time.  

Jay Orman Yes, my 75 yo mother has been following it for 2 months and her diabetes factors have decreased by about 10%

martino lorenzon I take 2 g each of NAC and glycine at bedtime and another 1 g of NAC and 1.5 g of glycine when I get up to use the restroom about 4 or 5 hours later.  I believe that I may have had a very slight improvement in sleep quality since adding this to my previous (and current) 3 mg of 6 hour extended time release melatonin and 4.5 g of ashwagandha at bedtime.  Hope that helps! 

martino lorenzon The solution would be to take something like wellbutrin or low-dose selegiline which I believe should be considered anyway after the age of >35.