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Re: Fisetin to Clear Senescent Cells @Chris M No.
- Iðunn
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- 2 yrs ago
- Self-Experimentation
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Re: Fisetin to Clear Senescent Cells @Chris M You apear to be confusing the nugatory life extension the ITP reported with massive levels of glycine alone, with the recent report on GlyNAC, which was not from the ITP and was a BS study.…
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- Iunn
- 2 yrs ago
- Self-Experimentation
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Re: Rejuvant? @Ozone8 I'm surprised you found this difficult. Here are the ingredients in the men's and women's formulas.
- Iðunn
- Iunn
- 2 yrs ago
- General Discussion
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Re: Rejuvant? @Fred Cloud @Fred Cloud said: Whats the purpose in all of that? Why not just take a couple of grams rather than squeezing the life out of the 1 gram? Because, as he explained, @Chuck Frasher said:…
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- 3 yrs ago
- General Discussion
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Re: Rejuvant? @Fred Cloud @Fred Cloud said: So you admit you are paying extra for branding. So I am correct. You stated, flatly, that they were using Ca-AKG because "they just want something unique that they can…
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- 3 yrs ago
- General Discussion
- Reported - view
Re: Rejuvant? @Fred Cloud said: Its the ca-akg that creates the sustained release, This is incorrect. Ca-AKG is just an AKG salt; it has negligible effects on pharmacokinetics.…
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- 3 yrs ago
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- General Discussion
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Re: Fisetin to Clear Senescent Cells @Robert Olin @Robert Olin said: I just heard Er, and where did you hear this? @Robert Olin said: quercetin with a bio-available zinc does the same as HCQ in that it escorts the zinc into the cell to…
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- 3 yrs ago
- Self-Experimentation
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Re: Rapamycin, etc. at 3pm EST today Q&A: Dr. Richard Miller Did this ever happen? The link is for an announcement of the discussion, but no discussion with Dr. Miller follows.
- Iðunn
- Iunn
- 3 yrs ago
- General Discussion
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Re: Fisetin to Clear Senescent Cells @Iðunn Ah: I see you posted it here. Thanks, @JGC .
- Iðunn
- Iunn
- 4 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @JGC Hm. It'd be great if you could track this down...
- Iðunn
- Iunn
- 4 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Michael Avenoso They don't present any studies showing this improved absorption; I would phone them and ask them for their evidence before taking this statement at face value.…
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- Iunn
- 4 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @garland That doesn't necessarily follow. They may be concerned that a beneficial effect of rapamycin (Sirolimus) may be mistaken for a beneficial effect of fisetin.
- Iðunn
- Iunn
- 4 yrs ago
- 1
- Self-Experimentation
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Re: Fisetin to Clear Senescent Cells @Staffan Olsson Ding ding! There's a lot of sleight of hand in this company's marketing.
- Iðunn
- Iunn
- 4 yrs ago
- Self-Experimentation
- Reported - view
Re: Rejuvant? @JGC said: the Rejuvenant claim about producing a DNAm clock reset is very questionable, because they used a nonstandard clock, possibly tailored to show a maximum effect.…
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- 4 yrs ago
- 1
- General Discussion
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Re: Rejuvant? @Jim N There are a number of rodent lifespan studies and human epidemiological studies suggesting decreased rather than increased lifespan from multivitamins (especially high-dose multis like LE…
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- Iunn
- 4 yrs ago
- 1
- General Discussion
- Reported - view
Re: Rejuvant? @Fred Cloud I respect the hell out of Brian Kennedy and Gordon Lithgow, and the animal study is very interesting. However, the epigenetic age clock used in the PDLH "study" is really shoddy and has…
- Iðunn
- Iunn
- 4 yrs ago
- 1
- General Discussion
- Reported - view
Re: Rejuvant? @Staffan Olsson That is the full text — but behind a pay-wall. I was hoping someone had access to a copy (university students and staff, etc). Thanks for following up.
- Iðunn
- Iunn
- 4 yrs ago
- General Discussion
- Reported - view
Re: Rejuvant? @Staffan Olsson Thanks. I was actually aware of that. That's of course the preprint, not the text as it was finally published (let alone the formatting changes); would anyone please post the final,…
- Iðunn
- Iunn
- 4 yrs ago
- General Discussion
- Reported - view
Re: Rejuvant? @Staffan Olsson Does anyone have a copy of the full text of this paper? Would you please attach it to a post?
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- Iunn
- 4 yrs ago
- General Discussion
- Reported - view
Re: Rejuvant? @Paul Beauchemin @Paul Beauchemin said: Brian Kennedy spoke at an online Longevity conference in London in March Would you please link the website for this conference,…
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- Iunn
- 4 yrs ago
- General Discussion
- Reported - view
Re: Fisetin to Clear Senescent Cells @RAW said: As I understand it, Fisetin does not attack cells of any kind, it simply removes the covering or "camouflage" coating that hides senescent cells from macrophages and prevents them from…
- Iðunn
- Iunn
- 4 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Simone Maher @Jacques Mathieu That 4x bioavailability is totally unverified: they haven't actually done any testing on their product, but are pulling numbers from studies of other polyphenols, B12,…
- Iðunn
- Iunn
- 4 yrs ago
- Self-Experimentation
- Reported - view
Re: Introduction to Young Plasma Infusions @BrianMDelaney I suspect Fred's doctor may actually have been offering (non-age-specific) platelet-rich plasma (PRP), an unproven stock-in-trade of sports medicine and anti-aging quakery.
- Iðunn
- Iunn
- 4 yrs ago
- Young Plasma Infusions
- Reported - view
Re: Fisetin to Clear Senescent Cells @Joe smith @BobM @Gary_Gilley @Paul_Beauchemin @Van This thread is for the use of fiseting for clearance of senescent cells. If you guys want to talk statins, or rapamycin, or sourcing for dasatinib,…
- Iðunn
- Iunn
- 4 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Dan said: For example during a fast, at day 5 is when it's clinically been measured that heavy senolytic activity occurs. What's your evidence for this?…
- Iðunn
- Iunn
- 4 yrs ago
- 1
- Self-Experimentation
- Reported - view

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