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Re: Did anyone experience acute inflammation after senolytics? Yes, definitely a worsening of symptoms, joint and bone pains, general "off" feeling after F+Q+P (black pepper) dissolved in oil for 3 consecutive days.…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @JGC Yes, the structure of Fisetin is said to be very close to that of Quercetin. That's one reason that I initially decided to add Quercetin to the Fisetin for the protocol.…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @JGC @Iðunn https://www.hindawi.com/journals/omcl/2015/854015/ Interactions between CYP3A4 and Dietary Polyphenols https://www.ncbi.nlm.nih.gov/pubmed/12130727 Piperine,…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Iðunn I based my use of piperine based on a reference I saw that stated that piperine from black pepper inhibited the liver's ability to break down certain drugs,…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Staffan Olsson I decided to add curcumin to my fisetin+quercetin+black pepper dissolved in olive oil for my second trial (one month after the first one).…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Monitoring Senescent Cell Clearance with Cytokine Levels @BobM I can only refer you to this link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804402/ A simple practice guide for dose conversion between animals and human
- Dan Nave
- Dan_Nave
- 5 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @karl kuffner I'm not sure that anyone can advise you of that at this time. The large doses of substances to function as synolytics should be done intermittently because they kill off senile cells…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Monitoring Senescent Cell Clearance with Cytokine Levels @murray flewelling There are many scholarly articles that show up if you search for 'Fisetin and Senolytic' for instance. You can modify your search with 'Quercetin' or 'Dasatinib' etc for even more.…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Introduction to senolytics @JGC Great article in Analog.
- Dan Nave
- Dan_Nave
- 5 yrs ago
- 1
- Senolytics Discussion
- Reported - view
Re: Monitoring Senescent Cell Clearance with Cytokine Levels @murray flewelling wrote: "Has there been any animal tests with Fisetin? I am skeptical of that working because I would have thought anything naturally occurring would have been discovered if it had…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @JGC I took 1/4 teaspoon of ground black pepper along with 1g fisetin and ~1g quercetin dissolved in oil, for 3 consecutive days (on an empty stomach).…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- 2
- Self-Experimentation
- Reported - view
Re: Dasatinib @RobH I was going to pay with a bank transfer so they had to communicate the details with me before I ordered. Then the person who talked to me asked for a prescription which I didn't have.…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Dasatinib @JGC Did Bon Hoa require a prescription from you, and if so how did you get on for this off label use?
- Dan Nave
- Dan_Nave
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Dasatinib @Peter5.0 Were you successful in ordering? They required a prescription from me for the same thing, but I did not have one. How would I get a prescription for this off label use?
- Dan Nave
- Dan_Nave
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Dasatinib @RobH Did you have a prescription for the dasatinib? I just tried to order some from BonHoa and they required a prescription.
- Dan Nave
- Dan_Nave
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @JGC I bought my fisetin from Swansonvitamins.com. It cost $11 to $12 something for 30 100mg capsules. I have been happy with purchases from swanson. I have never purchased from Alibaba.…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @JGC It is not clear how much fisetin is in this product. They do not rate it or guarantee it. It may be better to buy from Alibaba if you want bulk fisetin.
- Dan Nave
- Dan_Nave
- 5 yrs ago
- 2
- Self-Experimentation
- Reported - view
Re: ALA/ALC We have found this combination to be very effective for a relative with Parkinson's disease and it has improved that person's mental acuity tremendously. We give 100 mg ALA with 1000 mg ALC.…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells I'm sort of surprised that everyone seems to be just swallowing these capsules (fisetin and quercetin) presumably with water. Since these substances aren't very water soluble it would seem that they…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- 3
- Self-Experimentation
- Reported - view

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Dan Nave

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