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Re: Fisetin to Clear Senescent Cells @RAW My feeling is that even if it is true that quercetin is not senolytic, it might be valuable to take it along with the fisetin. My reasoning is that it has a "a moderate to strong inhibitory…
- Dan Nave
- Dan_Nave
- 4 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Dasatinib @Michael Avenoso Also, I should mention that although I think I took too strong a dose, I felt I got some indication of senolytic activity as I noticed a distinct improvement in a shoulder I was…
- Dan Nave
- Dan_Nave
- 4 yrs ago
- Self-Experimentation
- Reported - view
Re: Dasatinib @Michael Avenoso I have no reason to doubt that their dasatinib was legit. Side effects matched right down the line...
- Dan Nave
- Dan_Nave
- 4 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Dasatinib @Mel You could try TLR, True LIfe Research, but you would have to be willing and able to measure it out yourself. Sold as a powder.
- Dan Nave
- Dan_Nave
- 4 yrs ago
- Self-Experimentation
- Reported - view
Re: Senolytics @Sam Biller Is both the dasatinib and quercetin taken in split doses? eg: 50 mg D and 500 mg Q, taken twice a day?
- Dan Nave
- Dan_Nave
- 4 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Kaufmann Protocol Analysis If you are taking alpha lipoic acid for brain mitochondrial protection you may want to combine it with acetyl-L-carnitine. Check out this link. Combined R-α–lipoic acid and acetyl-L-carnitine exerts…
- Dan Nave
- Dan_Nave
- 4 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Is it safe/beneficial to do vigorous exercise while doing a 4 day water fast? No, it is not recommended.
- Dan Nave
- Dan_Nave
- 4 yrs ago
- Questions & Answers
- Reported - view
Re: How to increase the bioavailability of Fisetin @JGC Why are you talking the BioPerine one hour ahead of the senolytics? Why not at the same time? I have seen nothing that indicates that it should be taken one hour before the other supplements.
- Dan Nave
- Dan_Nave
- 4 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Resveratrol -- value, dose, source? Compared to resveratrol alone, combination with piperine was found to increase the degree of exposure to 229 percent, and the maximum levels in the blood by a whopping 1,544 percent.…
- Dan Nave
- Dan_Nave
- 4 yrs ago
- 2
- Self-Experimentation
- Reported - view
Re: Key Studies and Articles Referring to the Dasatinib and Quercetin study, does anyone know why they gave a single 100 mg daily dose of D and split the daily Q dosage into two 500 mg doses?…
- Dan Nave
- Dan_Nave
- 4 yrs ago
- General Discussion
- Reported - view
Re: Newbie here! Which Dasatinib protocol are you intending to use?
- Dan Nave
- Dan_Nave
- 5 yrs ago
- General Discussion
- Reported - view
Re: Newbie here! I think more, rather than less, effective. All 3 substances are CYP3A4 enzyme inhibitors. This enzyme also affects Dasatinib. Curcumin is a possible synolytic in its own right.…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- General Discussion
- Reported - view
Re: Fisetin to Clear Senescent Cells @Mermaid What is the recommendation for Dasatinib and Quercetin as per the 2018 Life Extension publication Age Reversal Update that you refer to? I am not able to find what this is.…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Koo Milk takes up to 4 hours to digest. When it hits the stomach it immediately curdles and forms a mass which slows its digestion. Anything taken with milk or mixed with milk will likewise take a…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Senolytics Results? Side effects?
- Dan Nave
- Dan_Nave
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Cell Death Mechanisms Behind D+Q and Fisetin Senolytics I forgot to mention in the post above that I took these for three days in a row. Other considerations (in my opinion): Take away from other medications. Stop other supplements for this time.…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Cell Death Mechanisms Behind D+Q and Fisetin Senolytics @Staffan Olsson I concur with your insights here. I like 1 gram each of F + C mixed in 1 Tablespoon olive oil with 1/2 teaspoon of freshly ground black pepper, taken immediately.…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Cell Death Mechanisms Behind D+Q and Fisetin Senolytics I got plenty of symptoms with 1 gram Fisetin and 1 gram of Quercetin mixed in 1 Tablespoon olive oil with 1/2 teaspoon of ground black pepper, taken on an empty stomach for three day.…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells There's no point in taking Fisetin with water. Mix it with oil, or a fatty meal.
- Dan Nave
- Dan_Nave
- 5 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells I like olive oil, but I have used other oil such as you would have in your kitchen for baking etc. Surprisingly, with the Fisiten and Quercetin it wasn't bad tasting and none of that unpleasantness…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells When doing Fisetin and Quercetin senolytic doses consider dissolving the powders in oil before taking. You could try with or without black pepper or piperine, etc. to see if that makes a difference.…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: How to increase the bioavailability of Fisetin @BobM I had absolutely no problem in dissolving my Swanson Fisetin (Novusetin), 1 gram in 1 Tablespoon of room temp olive oil. I also dissolved 1 gram each of Quercetin and Curcumin in the same oil.…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: How to increase the bioavailability of Fisetin @JGC That sounds good. I had absolutely no problem dissolving my Swanson (Novusetin) Fisetin in room temp olive oil, and also it worked with another kitchen/cooking oil I had when I ran out of olive…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: How to increase the bioavailability of Fisetin @JGC How do you plan to use the Fisetin? That is an awful lot for senolytic doses. Will you also take smaller doses daily?
- Dan Nave
- Dan_Nave
- 5 yrs ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells The F + Q + C (at approx. 1 gm each, in oil) + black pepper (approx. 1/2 tsp) seemed to be a little extreme for me, possibly because of the 50% increase of the quantity of senolytics taken with the…
- Dan Nave
- Dan_Nave
- 5 yrs ago
- Self-Experimentation
- Reported - view

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