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Re: Warning for those considering Rapamycin.news @Michael_666 Why not use your previous handle, Hypochondriac Michael Berger? As you know, I voiced my opinion on Rapamycin news that I thought your views were worth considering. And I still do.…
- chuck stanley
- chuck_stanley
- 1 mth ago
- 1
- General Discussion
- Reported - view
Re: The DIM Supplement and Wound Healing I dont remember the half life of DIM, probably will be fine as long as they are a few days apart would be my guess. And of course it also interacts with statins.
- chuck stanley
- chuck_stanley
- 3 mths ago
- Self-Experimentation
- Reported - view
Re: Norvaline I couldnt understand why research on such a promising supplement seemed to show no follow up. I found this on Medical Express: "People taking the protein supplement L-norvaline should be aware of…
- chuck stanley
- chuck_stanley
- 3 mths ago
- Questions & Answers
- Reported - view
Re: Deleted posts I see plenty of mentions that weren't deleted. So probably not.
- chuck stanley
- chuck_stanley
- 5 mths ago
- Questions & Answers
- Reported - view
Re: Fisetin to Clear Senescent Cells @Moonlitnight I have bought from Hansen, they are very good. Their spermidine tastes fine, very neutral, and can easily be mixed into a smoothie. I didnt realize they had fisetin...I need some.
- chuck stanley
- chuck_stanley
- 6 mths ago
- 1
- Self-Experimentation
- Reported - view
Re: Fisetin experimentation one year (reposted as topic for info purposes) @Michael_B By spinal decompression, did that include use of an inversion table? Did you find that the increased disc height was reflected in your overall height?
- chuck stanley
- chuck_stanley
- 6 mths ago
- Senolytics Discussion
- Reported - view
Re: My 80 year old father's proposed regimen. What do you think? @JGC Yeh, that looks like the google translation I saw. 😊
- chuck stanley
- chuck_stanley
- 6 mths ago
- Self-Experimentation
- Reported - view
Re: My 80 year old father's proposed regimen. What do you think? Can you please repost in English. My Google translation didnt make sense.
- chuck stanley
- chuck_stanley
- 6 mths ago
- Self-Experimentation
- Reported - view
Re: My 80 year old father's proposed regimen. What do you think? @Peter H. Howe "There is no question that metformin significantly inhibits hormone production based on a number of publications". I wasnt aware of that. Do you have a link to some in vivo studies?
- chuck stanley
- chuck_stanley
- 6 mths ago
- Self-Experimentation
- Reported - view
Re: My 80 year old father's proposed regimen. What do you think? If you compare the side effects of metformin with the benefits, its not much of a contest, as reflected in the following recent article. https://academic.oup.…
- chuck stanley
- chuck_stanley
- 6 mths ago
- Self-Experimentation
- Reported - view
Re: The DIM Supplement and Wound Healing @Jay Orman No problem, I'm not either. We're all here to learn from what others have learned. CYP3A4 is an important enzyme found mainly in the intestine and liver.…
- chuck stanley
- chuck_stanley
- 7 mths ago
- Self-Experimentation
- Reported - view
Re: The DIM Supplement and Wound Healing Great find! I have a lot of DIM leftover after I stopped taking it for prostate health due to its inducing CYP3A4. https://pubmed.ncbi.nlm.nih.gov/25542144/ "Together,…
- chuck stanley
- chuck_stanley
- 7 mths ago
- 1
- Self-Experimentation
- Reported - view
Re: Rapamycin - progress so far @Ulf Rasmusson Yes, 2 per day, but since it contains silymarin I only take 1/d. I've found in the past that too much silymarin gives me diarrhea.
- chuck stanley
- chuck_stanley
- 8 mths ago
- Self-Experimentation
- Reported - view
Re: Rapamycin - progress so far @Ulf Rasmusson This is the blend he recommended, Mushroom Synergy: https://www.amazon.com/gp/product/B081QKG76Q/ref=ppx_yo_dt_b_search_asin_image?ie=UTF8&psc=1
- chuck stanley
- chuck_stanley
- 8 mths ago
- Self-Experimentation
- Reported - view
Re: Rapamycin - progress so far @Ulf Rasmusson My neutraphil % went up but my lymph% came down, dropping below normal range with rapa so my doctor recommended a mushroom formula. It will be some months before I know if it worked.
- chuck stanley
- chuck_stanley
- 8 mths ago
- Self-Experimentation
- Reported - view
Re: Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin inhumans? @Staffan Olsson thanks for the link. Since cellulose doesnt readily dissolve, what have you found to be a convenient way to take the spermidine? How about the apigenin?
- chuck stanley
- chuck_stanley
- 8 mths ago
- General Discussion
- Reported - view
Re: Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin inhumans? @brad Since the wheat germ didnt work out for me as a smoothie additive, I still have it hanging around. I've never had cacao nibs. Its described as bitter... makes it sound sort of unappetizing.…
- chuck stanley
- chuck_stanley
- 8 mths ago
- General Discussion
- Reported - view
Re: SGLT2 @Fred Cloud @Peter H. Howe is this it? https://youtu.be/VHs_2Dv8MkU
- chuck stanley
- chuck_stanley
- 9 mths ago
- 1
- General Discussion
- Reported - view
Re: Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin inhumans? @joseph mikhael Yes, its not extract. Just be aware of the fact that it is not 10mg of spermidine. Its 10mg of spermidine trihydrochloride, which as I recall is about 60% spermidine.
- chuck stanley
- chuck_stanley
- 9 mths ago
- General Discussion
- Reported - view
Re: Rapamycin Cost @Chris Los you may have found, as I recently have, that sirolimus powder is degraded in the stomach. Sirolimus must make it to the small intestine in order to be absorbed.…
- chuck stanley
- chuck_stanley
- 10 mths ago
- Self-Experimentation
- Reported - view
Re: D+Q+F+P+L+G+GLA: A New Senolytic Cocktail @JGC I'm not sure. I am confused by the following publications I found: Piperine, a major constituent of black pepper, inhibits human ... https://pubmed.ncbi.nlm.nih.gov › ...…
- chuck stanley
- chuck_stanley
- 10 mths ago
- Self-Experimentation
- Reported - view
Re: D+Q+F+P+L+G+GLA: A New Senolytic Cocktail Thanks for the detailed report. In the future do you plan to continue the same cocktail, or will you make modifications based on this experience? Have you calculated the effective dosages based on…
- chuck stanley
- chuck_stanley
- 10 mths ago
- Self-Experimentation
- Reported - view
Re: Fisetin to Clear Senescent Cells @Peter H. Howe Twenty five pullups at any age is impressive. At age 81 its scary!
- chuck stanley
- chuck_stanley
- 10 mths ago
- 1
- Self-Experimentation
- Reported - view
Re: Is interested in life extension a male thing? Interesting observation. Its been shown that, in general, males are greater risk takers. I suppose the conservative view would be that life extension measures are risky unless prescribed by your…
- chuck stanley
- chuck_stanley
- 10 mths ago
- Questions & Answers
- Reported - view
Re: Rapamycin Cost If you have access to inexpensive testing I could see using Chinese powders. But if the company is a trading company in that product, as most seem to be,…
- chuck stanley
- chuck_stanley
- 10 mths ago
- 1
- Self-Experimentation
- Reported - view

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