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Age Reversal Forum

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Re: Exercise Mimetics
@Jack Black Good to hear research continues on Irisin. It looks like that company with GW1516 ships to the USA - if anyone tries it, please post results: https://www.peakbody.co.…
- Brin_Chikovski
- 4 yrs ago
- Self-Experimentation
- Reported - view
Re: Exercise Mimetics
Unfortunately, Irisin didn't work out: https://www.stuff.co.nz/life-style/well-good/72003385/irisin-the-miracle-fat-pill-that-never-was-and-the-downside-it-exposed
- Brin_Chikovski
- 4 yrs ago
- Self-Experimentation
- Reported - view
Re: New Spermidine Paper: Dietary spermidine improves cognitive function
A related article: https://www.the-scientist.com/news-opinion/dietary-spermidine-boosts-cognition-in-insects-and-rodents-68670
- Brin_Chikovski
- 4 yrs ago
- Self-Experimentation
- Reported - view
New Spermidine Paper: Dietary spermidine improves cognitive function

Full Paper Here: https://www.cell.com/cell-reports/fulltext/S2211-1247(21)00299-0 Highlights Elevated spermidine intake improves cognitive function in flies and mice Dietary spermidine intake…
- Brin_Chikovski
- 4 yrs ago
- 1reply
- 146
- Self-Experimentation
Re: Has anyone tried urolithin A?
@Geoff Welch Thanks for the info. Did you get HPLC analysis done on the China Urolithin A? What was the purity? How much did you buy at once?
- Brin_Chikovski
- 4 yrs ago
- Self-Experimentation
- Reported - view
Re: Rapamycin Cost in India
@Sheila Out I wouldn't recommend Biocon Sirolimus. I purchased it and had it tested here in a lab and there were unknown compounds in it that were not in the other medications I tested.…
- Brin_Chikovski
- 4 yrs ago
- General Discussion
- Reported - view
Re: Rapamycin Cost in India
@Betty Bennett Email them and ask them if they can get it for you and the price they will charge. Like with all resellers - sometimes they have stock, other times not.
- Brin_Chikovski
- 4 yrs ago
- General Discussion
- Reported - view
Re: Rapamycin Cost in India
@Cynda Its interesting - I was not aware of that scam advisor website - but you are right, Indiamart rates poorly: https://www.scamadviser.com/check-website/indiamart.…
- Brin_Chikovski
- 4 yrs ago
- General Discussion
- Reported - view
Re: Rapamycin Cost in India
@Paul Beauchemin Hi Paul - help me understand this - how did Indiamart scam you? They are just a search engine, not a site that actually sells anything.…
- Brin_Chikovski
- 4 yrs ago
- General Discussion
- Reported - view
Re: Rapamycin Cost in India
Indiamart.com is just a platform - where you can search for vendors. I've ordered medicines about 8 times from different vendors on the site, and I've had labs do HPLC analysis on the actual drugs…
- Brin_Chikovski
- 4 yrs ago
- 2
- General Discussion
- Reported - view
Re: Rapamycin Cost in India
Just search on sirolimus on indiamart.com - many vendors, typical cost $1 to $1.50 per 1 mg tablet.
- Brin_Chikovski
- 4 yrs ago
- 1
- General Discussion
- Reported - view
Re: linda
@linda little I have gotten my sirolimus from India tested using Valisure.com a number of times - but I'm not sure if they are providing their testing service to people like us right now - I think…
- Brin_Chikovski
- 4 yrs ago
- Self-Experimentation
- Reported - view
Re: Rapamycin Cost
@Cynda Wow - 5mg WITH grapefruit juice - that is a very high dose to start with. Grapefruit juice effectively triples (approx) your dosage - so you're actually taking about 15mg a week - which is…
- Brin_Chikovski
- 4 yrs ago
- Self-Experimentation
- Reported - view
Re: Has anyone tried urolithin A?
A good podcast on this topic: https://podcasts.google.com/feed/aHR0cHM6Ly93d3cuaWhtYy51cy9zdGVtdGFsay9mZWVkL3BvZGNhc3Q/episode/aHR0cHM6Ly93d3cuaWhtYy51cy8_cG9zdF90eXBlPXN0ZW10YWxrJnA9ODYzODQ?…
- Brin_Chikovski
- 4 yrs ago
- 1
- Self-Experimentation
- Reported - view
Re: Do doctors prescribe rapamycin to people in their 20s?
No real need to start in your 20s... in the clinical studies the life extension in mice was not that different if rapamycin was started earlier in life vs. mid or later.…
- Brin_Chikovski
- 4 yrs ago
- 2
- Self-Experimentation
- Reported - view
Re: linda
I just search for sirolimus on Indiamart.com - there are lots of vendors there. Availability comes and goes depending on their stock, etc. No prescription required. Cost about $1 to $1.…
- Brin_Chikovski
- 4 yrs ago
- Self-Experimentation
- Reported - view
Re: linda
I purchased Biocon sirolimus and had it lab tested at valisure.com - and the batch I purchased seemed to be of lower quality than the Zydus sirolimus batch I purchased. I"Ve done this a few times.…
- Brin_Chikovski
- 4 yrs ago
- Self-Experimentation
- Reported - view
Re: Richard Miller on Peter Attia podcast regarding rapamycin
@Van Van - how does it work there... do you need a prescription from a doctor or can you just walk in and buy it (Acarbose) over the counter?
- Brin_Chikovski
- 4 yrs ago
- 1
- Rapamycin Discussion
- Reported - view
Re: Richard Miller on Peter Attia podcast regarding rapamycin
@Van Great price on Acarbose - can you share an online source?
- Brin_Chikovski
- 4 yrs ago
- 1
- Rapamycin Discussion
- Reported - view
Re: Rejuvant?
@Al m Rejuvant (and the studies done by the Buck Institute) are all Calcium AKG... not the other versions of AKG. The Rejuvant dosing is recommended 1 gram per day (2 tablets),…
- Brin_Chikovski
- 4 yrs ago
- 1
- General Discussion
- Reported - view
Re: Richard Miller on Peter Attia podcast regarding rapamycin
@Al m Yes - I agree, and probably more cost-effective. Or, Perhaps a balance of the two (Or alternating) to minimize side effect risk?
- Brin_Chikovski
- 4 yrs ago
- 1
- Rapamycin Discussion
- Reported - view
Re: 17a-Estradiol - Great Anti-aging, but Will It Ever Become a Product
@Paul Beauchemin Its available all over the internet... just search on 17a-Estradiol CAS: 57-91-0 eg... https://www.chemservice.com/17a-estradiol-n-14023-100mg.…
- Brin_Chikovski
- 4 yrs ago
- 1
- General Discussion
- Reported - view
Re: Richard Miller on Peter Attia podcast regarding rapamycin
@Van I'm just going by the NIH ITP Study results - I'm just a biohacker like you, so I can't recommend anything - I'm using Rap and Acarbose and may try Canagliflozin once I have a continuous…
- Brin_Chikovski
- 4 yrs ago
- 2
- Rapamycin Discussion
- Reported - view
17a-Estradiol - Great Anti-aging, but Will It Ever Become a Product

17a-Estradiol has been one of the top performers in the NIH ITP anti-aging drug studies, But - its never been tested. I'm wondering if there will ever be the human clinical studies done if (since it…
- Brin_Chikovski
- 4 yrs ago
- 11replies
- 320
- 2
- General Discussion
Re: Richard Miller on Peter Attia podcast regarding rapamycin
@Van In the NIH ITP Lifespan studies it seems that Acarbose and Canagliflozin were much better results that metformin... I took Metformin before, but have moved over just based on the data.…
- Brin_Chikovski
- 4 yrs ago
- 1
- Rapamycin Discussion
- Reported - view

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