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Re: Regenerative medicine from the future
https://directorsblog.nih.gov/tag/tissue-nanotransfection/ Year 2019 article
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
General Discussion
Reported - view
Re: Regenerative medicine from the future
2017 news so what happened? Completely no news since then?
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
General Discussion
Reported - view
Re: Repair Glycation products in tissues?
I've to refresh my knowledge about other treatments but what comes to mind immediately is shock treatments. Heat shock and cold shock treatments. That refers to things like hot pools, saunas,…
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
General Discussion
Reported - view
Re: Treatment for Reducing Arterial Plaque and Imflammatory Cells:
How I Reversed 20 Years of Arterial Plaque https://youtu.be/QOWF0KTNu2g
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
1
General Discussion
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Re: Grey hair as a senescence detector?
@Chan Taking senolytics, boosting NAD+ levels with niacin, metformin for AMPK... These are low hanging fruits. Turning white hair black, if there's something safe I can take to try that, sure,…
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
1
Assessing Biological Age
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Re: Fisetin experimentation one year (reposted as topic for info purposes)
@Andrew Whitfield Fisetin does not "choose selectively" to destroy senescent cells. So why does taking fisetin remove senescent cells? The simple answer is that your own genes remove senescent cells.…
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
2
Senolytics Discussion
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Re: Fisetin experimentation one year (reposted as topic for info purposes)
Unlike chemo drugs that directly target and kill cells, fisetin does not do that. What it does is that it induces cell death. In other words, it encourages the body to remove senescent cells.…
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
1
Senolytics Discussion
Reported - view
Re: Treatment for Reducing Arterial Plaque and Imflammatory Cells:
I swear by intermittent fasting in reducing inflammation. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257368/
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
3
General Discussion
Reported - view
Re: Are epigenetic tests accurate?
The point is to have a baseline number and then compare to that baseline number. So if you obtained the baseline number with urine, then, a year later, get the new numbers with urine.…
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
Assessing Biological Age
Reported - view
Re: Grey hair as a senescence detector?
Hair turns gray as pigment cells stop producing melanin. Why bother with reversing grey hair? It would be more important to reverse heart, kidneys and brain, for examples.…
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
1
Assessing Biological Age
Reported - view
Re: hair growth tips
For men, propecia, the prostate cancer drug, is proven to work for pattern balding.
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
General Discussion
Reported - view
Re: Sources of dasatinib
@Randy B Interpretation “Hit-and-run” treatment with senolytics, which in the case of D + Q have elimination half-lives <11 h, significantly decreases senescent cell burden in humans The studies are…
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
Senolytics Discussion
Reported - view
Re: Sources of dasatinib
@Randy B Abstract Background Senescent cells, which can release factors that cause inflammation and dysfunction, the senescence-associated secretory phenotype (SASP),…
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
Senolytics Discussion
Reported - view
Re: Sources of dasatinib
@Randy B You know there is the dictum, "First do no harm." Did you read the side effects of Dasatinib? http://chemocare.com/chemotherapy/drug-info/dasatinib.…
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
Senolytics Discussion
Reported - view
Re: Sources of dasatinib
The doses are calculated and therefore implied from animals studies. It is calculated from the animal studies where the amount used for the animal divided by the weight of the animal multiply by…
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
Senolytics Discussion
Reported - view
Re: I recently started Metformin for IR, but am having a lot of gut issues,even after 2 weeks . Thoughts about other possible supplements?
@Robin Maisel It's a certain brand of metformin that I've been using for more than 10 years. I do not, and had never suffered from diabetes, by the way.…
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
General Discussion
Reported - view
Re: I recently started Metformin for IR, but am having a lot of gut issues,even after 2 weeks . Thoughts about other possible supplements?
Try Glucophage 500 mg a day. It is slow release. If you are not diabetic, there's no reason to do more than 500mg a day. Improve your microbiome.
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
General Discussion
Reported - view
Re: Is it me or is Apigenin not so hot in this forum
Judith Campisi if I remember correctly, she's the senescence expert, said in an interview, "Nobody really knows why people die." Some people get really sick and recovers but some get worse and die.…
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
Self-Experimentation
Reported - view
Re: Is it me or is Apigenin not so hot in this forum
The question then becomes, "How far back can humans age backwards and for how long is it possible, to do that?" I am 60 now and for sure, with tangible results (the planking) I have successfully age…
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
Self-Experimentation
Reported - view
Re: Is it me or is Apigenin not so hot in this forum
The point is, I can only do that AFTER doing aging reversal. This tells me that aging backwards is possible.
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
Self-Experimentation
Reported - view
Re: Too....much....information!!!
Do a little of everything. Start with things that you can do, not things that you can take. Things like Intermittent fasting. High intensity Intermittent exercises. Real whole foods diet.…
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
General Discussion
Reported - view
Re: Is it me or is Apigenin not so hot in this forum
See the link. I can hardly 2 minutes (as I remember) when I was 20 years old. After the aging backwards for a few years, I can do 4 minutes. I plank like less than 15 times my whole life,…
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
Self-Experimentation
Reported - view
Re: Is it me or is Apigenin not so hot in this forum
Sure, it will take longer than otherwise but it will also prevent any chance for an overdose. I can tell you my patience paid off.
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
Self-Experimentation
Reported - view
Re: Is it me or is Apigenin not so hot in this forum
I do not supplement with apigenin. I believe this: https://forum.age-reversal.net/t/m1h3pz1/insufficient-dosage-leads-to-no-effect-or-small-effect
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
Self-Experimentation
Reported - view
Re: Is it me or is Apigenin not so hot in this forum
An overdose of anything is bad for you. Usually, the first symptom is diarrhea if you are overdosing. If you do not have kidney and liver problems, your body will be able to handle it.…
Andrew P K Yap
Andrew_P_K_Yap
4 yrs ago
Self-Experimentation
Reported - view
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